Assessing the sensitivity of [11C]p943, a novel 5-HTIB radioligand, to endogenous serotonin release

Synapse

Volumn 65, Issue 10, 2011, Pages 1113-1117

  Cosgrove, Kelly P ^a,b   Kloczynski, Tracy ^a,b   Nabulsi, Nabeel ^b   Weinzimmer, David ^b   Lin, Shu Fei ^b   Staley, Julie K ^a,b   Bhagwagar, Zubin ^a,c   Carson, Richard E ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

^c BRISTOL MYERS SQUIBB   (United States)

Author keywords

5HT1B; 11C P943; Nonhuman primate; PET; Serotonin

Indexed keywords

FENFLURAMINE; P 943; P 943 C 11; RADIOLIGAND; SEROTONIN; SEROTONIN 1B RECEPTOR; UNCLASSIFIED DRUG; 1 (4 (2 METHOXYISOPROPYL)PHENYL) 3 (2 (4 METHYLPIPERAZIN 1 YL)BENZYL)PYRROLIDIN 2 ONE; 1-(4-(2-METHOXYISOPROPYL)PHENYL)-3-(2-(4-METHYLPIPERAZIN-1-YL)BENZYL)PYRROLIDIN-2-ONE; 2 PYRROLIDONE DERIVATIVE; CARBON; DIAGNOSTIC AGENT; LIGAND; PIPERAZINE DERIVATIVE; SEROTONIN ANTAGONIST;

ANIMAL EXPERIMENT; ARTICLE; BABOON; DRUG RECEPTOR BINDING; FEMALE; IMAGE ANALYSIS; ISOTOPE LABELING; MALE; NEUROIMAGING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RHESUS MONKEY; ANIMAL; BRAIN; HUMAN; METABOLISM; METHODOLOGY; PAPIO ANUBIS; PHYSIOLOGY; SCINTISCANNING; SECRETION; SENSITIVITY AND SPECIFICITY;

ANIMALS; BRAIN; CARBON RADIOISOTOPES; FEMALE; HUMANS; LIGANDS; PAPIO ANUBIS; PIPERAZINES; POSITRON-EMISSION TOMOGRAPHY; PYRROLIDINONES; RECEPTOR, SEROTONIN, 5-HT1B; SENSITIVITY AND SPECIFICITY; SEROTONIN; SEROTONIN ANTAGONISTS;

EID: 79960959970     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.20942     Document Type: Article

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