메뉴 건너뛰기




Volumn 7, Issue 7, 2011, Pages

Translation reinitiation relies on the interaction between eIFa/TIF32 and progressively folded cis-acting mRNA elements preceding short uORFS

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR 3A; MESSENGER RNA; PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; YAP1 PROTEIN; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; DNA BINDING PROTEIN; GCN4 PROTEIN, S CEREVISIAE; INITIATION FACTOR 3; RIBOSOME PROTEIN; RPG1 PROTEIN, S CEREVISIAE; RPS0A PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN;

EID: 79960959927     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002137     Document Type: Article
Times cited : (71)

References (40)
  • 1
    • 75149196287 scopus 로고    scopus 로고
    • The mechanism of eukaryotic translation initiation and principles of its regulation
    • Jackson RJ, Hellen CUT, Pestova TV, (2010) The mechanism of eukaryotic translation initiation and principles of its regulation. Nat Rev Mol Cell Biol 11: 113-127.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 113-127
    • Jackson, R.J.1    Hellen, C.U.T.2    Pestova, T.V.3
  • 2
    • 66149118241 scopus 로고    scopus 로고
    • Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans
    • Calvo SE, Pagliarini DJ, Mootha VK, (2009) Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans. PNAS 106: 7507-7512.
    • (2009) PNAS , vol.106 , pp. 7507-7512
    • Calvo, S.E.1    Pagliarini, D.J.2    Mootha, V.K.3
  • 3
    • 0022552131 scopus 로고
    • Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
    • Kozak M, (1986) Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell 44: 283-292.
    • (1986) Cell , vol.44 , pp. 283-292
    • Kozak, M.1
  • 4
    • 62549134121 scopus 로고    scopus 로고
    • Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling
    • Ingolia NT, Ghaemmaghami S, Newman JRS, Weissman JS, (2009) Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling. Science 324: 218-223.
    • (2009) Science , vol.324 , pp. 218-223
    • Ingolia, N.T.1    Ghaemmaghami, S.2    Newman, J.R.S.3    Weissman, J.S.4
  • 5
    • 48249118705 scopus 로고    scopus 로고
    • uORFs with unusual translational start codons autoregulate expression of eukaryotic ornithine decarboxylase homologs
    • Ivanov IP, Loughran G, Atkins JF, (2008) uORFs with unusual translational start codons autoregulate expression of eukaryotic ornithine decarboxylase homologs. PNAS 105: 10079-10084.
    • (2008) PNAS , vol.105 , pp. 10079-10084
    • Ivanov, I.P.1    Loughran, G.2    Atkins, J.F.3
  • 6
    • 70349536104 scopus 로고    scopus 로고
    • Evolutionary Roles of Upstream Open Reading Frames in Mediating Gene Regulation in Fungi
    • Hood HM, Neafsey DE, Galagan J, Sachs MS, (2009) Evolutionary Roles of Upstream Open Reading Frames in Mediating Gene Regulation in Fungi. Annual Review of Microbiology 63: 385-409.
    • (2009) Annual Review of Microbiology , vol.63 , pp. 385-409
    • Hood, H.M.1    Neafsey, D.E.2    Galagan, J.3    Sachs, M.S.4
  • 7
    • 27144555357 scopus 로고    scopus 로고
    • Regulation of translation via mRNA structure in prokaryotes and eukaryotes
    • Kozak M, (2005) Regulation of translation via mRNA structure in prokaryotes and eukaryotes. Gene 361: 13-37.
    • (2005) Gene , vol.361 , pp. 13-37
    • Kozak, M.1
  • 8
    • 27144510561 scopus 로고    scopus 로고
    • Translational regulation of GCN4 and the general amino acid control of yeast
    • Hinnebusch AG, (2005) Translational regulation of GCN4 and the general amino acid control of yeast. Annu Rev Microbiol 59: 407-450.
    • (2005) Annu Rev Microbiol , vol.59 , pp. 407-450
    • Hinnebusch, A.G.1
  • 9
    • 0035945260 scopus 로고    scopus 로고
    • Constraints on reinitiation of translation in mammals
    • Kozak M, (2001) Constraints on reinitiation of translation in mammals. Nucleic Acids Res 29: 5226-5232.
    • (2001) Nucleic Acids Res , vol.29 , pp. 5226-5232
    • Kozak, M.1
  • 10
    • 51149091031 scopus 로고    scopus 로고
    • eIF3a cooperates with sequences 5′ of uORF1 to promote resumption of scanning by post-termination ribosomes for reinitiation on GCN4 mRNA
    • Szamecz B, Rutkai E, Cuchalova L, Munzarova V, Herrmannova A, et al. (2008) eIF3a cooperates with sequences 5′ of uORF1 to promote resumption of scanning by post-termination ribosomes for reinitiation on GCN4 mRNA. Genes Dev 22: 2414-2425.
    • (2008) Genes Dev , vol.22 , pp. 2414-2425
    • Szamecz, B.1    Rutkai, E.2    Cuchalova, L.3    Munzarova, V.4    Herrmannova, A.5
  • 11
    • 0037154965 scopus 로고    scopus 로고
    • Gene-specific regulation by general translation factors
    • Dever TE, (2002) Gene-specific regulation by general translation factors. Cell 108: 545-556.
    • (2002) Cell , vol.108 , pp. 545-556
    • Dever, T.E.1
  • 12
    • 3843117589 scopus 로고    scopus 로고
    • Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells
    • Vattem KM, Wek RC, (2004) Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells. Proc Natl Acad Sci U S A 101: 11269-11274.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 11269-11274
    • Vattem, K.M.1    Wek, R.C.2
  • 13
    • 0028012044 scopus 로고
    • Effect of sequence context at stop codons on efficiency of reinitiation in GCN4 translational control
    • Grant CM, Hinnebusch AG, (1994) Effect of sequence context at stop codons on efficiency of reinitiation in GCN4 translational control. Mol Cell Biol 14: 606-618.
    • (1994) Mol Cell Biol , vol.14 , pp. 606-618
    • Grant, C.M.1    Hinnebusch, A.G.2
  • 14
    • 0028784458 scopus 로고
    • Sequences 5′ of the first upstream open reading frame in GCN4 mRNA are required for efficient translational reinitiation
    • Grant CM, Miller PF, Hinnebusch AG, (1995) Sequences 5′ of the first upstream open reading frame in GCN4 mRNA are required for efficient translational reinitiation. Nuc Acids Res 23: 3980-3988.
    • (1995) Nuc Acids Res , vol.23 , pp. 3980-3988
    • Grant, C.M.1    Miller, P.F.2    Hinnebusch, A.G.3
  • 15
    • 0037444342 scopus 로고    scopus 로고
    • The Yeast eIF3 Subunits TIF32/a and NIP1/c and eIF5 Make Critical Connections with the 40S Ribosome in vivo
    • Valášek L, Mathew A, Shin BS, Nielsen KH, Szamecz B, et al. (2003) The Yeast eIF3 Subunits TIF32/a and NIP1/c and eIF5 Make Critical Connections with the 40S Ribosome in vivo. Genes Dev 17: 786-799.
    • (2003) Genes Dev , vol.17 , pp. 786-799
    • Valášek, L.1    Mathew, A.2    Shin, B.S.3    Nielsen, K.H.4    Szamecz, B.5
  • 16
    • 79951510534 scopus 로고    scopus 로고
    • Crystal Structure of the Eukaryotic 40S Ribosomal Subunit in Complex with Initiation Factor 1
    • in press
    • Rabl J, Leibundgut M, Ataide SF, Haag A, Ban N, (2011) Crystal Structure of the Eukaryotic 40S Ribosomal Subunit in Complex with Initiation Factor 1. Science in press.
    • (2011) Science
    • Rabl, J.1    Leibundgut, M.2    Ataide, S.F.3    Haag, A.4    Ban, N.5
  • 17
    • 77956657467 scopus 로고    scopus 로고
    • The RNA Recognition Motif of Eukaryotic Translation Initiation Factor 3g (eIF3g) Is Required for Resumption of Scanning of Posttermination Ribosomes for Reinitiation on GCN4 and Together with eIF3i Stimulates Linear Scanning
    • Cuchalová L, Kouba T, Herrmannová A, Danyi I, Chiu W-l, et al. (2010) The RNA Recognition Motif of Eukaryotic Translation Initiation Factor 3g (eIF3g) Is Required for Resumption of Scanning of Posttermination Ribosomes for Reinitiation on GCN4 and Together with eIF3i Stimulates Linear Scanning. Mol Cell Biol 30: 4671-4686.
    • (2010) Mol Cell Biol , vol.30 , pp. 4671-4686
    • Cuchalová, L.1    Kouba, T.2    Herrmannová, A.3    Danyi, I.4    Chiu, W.5
  • 18
    • 0032029584 scopus 로고    scopus 로고
    • The yeast transcription factor genes YAP1 and YAP2 are subject to differential control at the levels of both translation and mRNA stability
    • Vilela C, Linz B, Rodrigues-Pousada C, McCarthy JE, (1998) The yeast transcription factor genes YAP1 and YAP2 are subject to differential control at the levels of both translation and mRNA stability. Nucleic Acids Res 26: 1150-1159.
    • (1998) Nucleic Acids Res , vol.26 , pp. 1150-1159
    • Vilela, C.1    Linz, B.2    Rodrigues-Pousada, C.3    McCarthy, J.E.4
  • 19
    • 0024710133 scopus 로고
    • Sequences that surround the stop codons of upstream open reading frames in GCN4 mRNA determine their distinct functions in translational control
    • Miller PF, Hinnebusch AG, (1989) Sequences that surround the stop codons of upstream open reading frames in GCN4 mRNA determine their distinct functions in translational control. Genes and Development 3: 1217-1225.
    • (1989) Genes and Development , vol.3 , pp. 1217-1225
    • Miller, P.F.1    Hinnebusch, A.G.2
  • 20
    • 0034705289 scopus 로고    scopus 로고
    • The RNA binding protein Pub1 modulates the stability of transcripts containing upstream open reading frames
    • Ruiz-Echevarria MJ, Peltz SW, (2000) The RNA binding protein Pub1 modulates the stability of transcripts containing upstream open reading frames. Cell 101: 741-751.
    • (2000) Cell , vol.101 , pp. 741-751
    • Ruiz-Echevarria, M.J.1    Peltz, S.W.2
  • 22
    • 4944226552 scopus 로고    scopus 로고
    • A new hydrogen-bonding potential for the design of protein-RNA interactions predicts specific contacts and discriminates decoys
    • Chen Y, Kortemme T, Robertson T, Baker D, Varani G, (2004) A new hydrogen-bonding potential for the design of protein-RNA interactions predicts specific contacts and discriminates decoys. Nucleic Acids Research 32: 5147-5162.
    • (2004) Nucleic Acids Research , vol.32 , pp. 5147-5162
    • Chen, Y.1    Kortemme, T.2    Robertson, T.3    Baker, D.4    Varani, G.5
  • 23
    • 0037112055 scopus 로고    scopus 로고
    • The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection
    • Pestova TV, Kolupaeva VG, (2002) The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection. Genes Dev 16: 2906-2922.
    • (2002) Genes Dev , vol.16 , pp. 2906-2922
    • Pestova, T.V.1    Kolupaeva, V.G.2
  • 24
    • 73549095535 scopus 로고    scopus 로고
    • C/EBPbetaDeltauORF mice - a genetic model for uORF-mediated translational control in mammals
    • Wethmar K, Begay V, Smink JJ, Zaragoza K, Wiesenthal V, et al. (2010) C/EBPbetaDeltauORF mice - a genetic model for uORF-mediated translational control in mammals. Genes & Development 24: 15-20.
    • (2010) Genes & Development , vol.24 , pp. 15-20
    • Wethmar, K.1    Begay, V.2    Smink, J.J.3    Zaragoza, K.4    Wiesenthal, V.5
  • 25
    • 0031975482 scopus 로고    scopus 로고
    • An activating splice donor mutation in the thrombopoietin gene causes hereditary thrombocythaemia
    • Wiestner A, Schlemper RJ, van der Maas APC, Skoda RC, (1998) An activating splice donor mutation in the thrombopoietin gene causes hereditary thrombocythaemia. Nat Genet 18: 49-52.
    • (1998) Nat Genet , vol.18 , pp. 49-52
    • Wiestner, A.1    Schlemper, R.J.2    van der Maas, A.P.C.3    Skoda, R.C.4
  • 26
    • 59149083659 scopus 로고    scopus 로고
    • Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis
    • Wen Y, Liu Y, Xu Y, Zhao Y, Hua R, et al. (2009) Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis. Nat Genet 41: 228-233.
    • (2009) Nat Genet , vol.41 , pp. 228-233
    • Wen, Y.1    Liu, Y.2    Xu, Y.3    Zhao, Y.4    Hua, R.5
  • 27
    • 0032900535 scopus 로고    scopus 로고
    • Mutation of the CDKN2A 5′ UTR creates an aberrant initiation codon and predisposes to melanoma
    • Liu L, Dilworth D, Gao L, Monzon J, Summers A, et al. (1999) Mutation of the CDKN2A 5′ UTR creates an aberrant initiation codon and predisposes to melanoma. Nat Genet 21: 128-132.
    • (1999) Nat Genet , vol.21 , pp. 128-132
    • Liu, L.1    Dilworth, D.2    Gao, L.3    Monzon, J.4    Summers, A.5
  • 28
    • 0034925040 scopus 로고    scopus 로고
    • A link between diabetes and atherosclerosis: Glucose regulates expression of CD36 at the level of translation
    • Griffin E, Re A, Hamel N, Fu C, Bush H, et al. (2001) A link between diabetes and atherosclerosis: Glucose regulates expression of CD36 at the level of translation. Nat Med 7: 840-846.
    • (2001) Nat Med , vol.7 , pp. 840-846
    • Griffin, E.1    Re, A.2    Hamel, N.3    Fu, C.4    Bush, H.5
  • 29
    • 33646244775 scopus 로고    scopus 로고
    • Leaky scanning and reinitiation regulate BACE1 gene expression
    • Zhou W, Song W, (2006) Leaky scanning and reinitiation regulate BACE1 gene expression. Mol Cell Biol 26: 3353-3364.
    • (2006) Mol Cell Biol , vol.26 , pp. 3353-3364
    • Zhou, W.1    Song, W.2
  • 31
    • 44649095899 scopus 로고    scopus 로고
    • Ribosomal position and contacts of mRNA in eukaryotic translation initiation complexes
    • Pisarev AV, Kolupaeva VG, Yusupov MM, Hellen CUT, Pestova TV, (2008) Ribosomal position and contacts of mRNA in eukaryotic translation initiation complexes. EMBO J 27: 1609-1621.
    • (2008) EMBO J , vol.27 , pp. 1609-1621
    • Pisarev, A.V.1    Kolupaeva, V.G.2    Yusupov, M.M.3    Hellen, C.U.T.4    Pestova, T.V.5
  • 32
    • 0035929148 scopus 로고    scopus 로고
    • A plant viral "reinitiation" factor interacts with the host translational machinery
    • Park HS, Himmelbach A, Browning KS, Hohn T, Ryabova LA, (2001) A plant viral "reinitiation" factor interacts with the host translational machinery. Cell 106: 723-733.
    • (2001) Cell , vol.106 , pp. 723-733
    • Park, H.S.1    Himmelbach, A.2    Browning, K.S.3    Hohn, T.4    Ryabova, L.A.5
  • 33
    • 77950243975 scopus 로고    scopus 로고
    • The h subunit of eIF3 promotes reinitiation competence during translation of mRNAs harboring upstream open reading frames
    • Roy B, Vaughn JN, Kim B-H, Zhou F, Gilchrist MA, et al. (2010) The h subunit of eIF3 promotes reinitiation competence during translation of mRNAs harboring upstream open reading frames. RNA 16: 748-761.
    • (2010) RNA , vol.16 , pp. 748-761
    • Roy, B.1    Vaughn, J.N.2    Kim, B.-H.3    Zhou, F.4    Gilchrist, M.A.5
  • 34
    • 34047263278 scopus 로고    scopus 로고
    • The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome
    • Passmore LA, Schmeing TM, Maag D, Applefield DJ, Acker MG, et al. (2007) The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome. Mol Cell 26: 41-50.
    • (2007) Mol Cell , vol.26 , pp. 41-50
    • Passmore, L.A.1    Schmeing, T.M.2    Maag, D.3    Applefield, D.J.4    Acker, M.G.5
  • 35
    • 36849080874 scopus 로고    scopus 로고
    • The mechanism of an exceptional case of reinitiation after translation of a long ORF reveals why such events do not generally occur in mammalian mRNA translation
    • Pöyry TA, Kaminski A, Connell EJ, Fraser CS, Jackson RJ, (2007) The mechanism of an exceptional case of reinitiation after translation of a long ORF reveals why such events do not generally occur in mammalian mRNA translation. Genes Dev 21: 3149-3162.
    • (2007) Genes Dev , vol.21 , pp. 3149-3162
    • Pöyry, T.A.1    Kaminski, A.2    Connell, E.J.3    Fraser, C.S.4    Jackson, R.J.5
  • 36
    • 59949087959 scopus 로고    scopus 로고
    • The importance of inter- and intramolecular base pairing for translation reinitiation on a eukaryotic bicistronic mRNA
    • Luttermann C, Meyers G, (2009) The importance of inter- and intramolecular base pairing for translation reinitiation on a eukaryotic bicistronic mRNA. Genes Dev 23: 331-344.
    • (2009) Genes Dev , vol.23 , pp. 331-344
    • Luttermann, C.1    Meyers, G.2
  • 38
    • 0033869876 scopus 로고    scopus 로고
    • Translational control of C/EBPa and C/EBPb isoform expression
    • Calkhoven CR, Muller C, Leutz A, (2000) Translational control of C/EBPa and C/EBPb isoform expression. Genes Dev 14: 1920-1932.
    • (2000) Genes Dev , vol.14 , pp. 1920-1932
    • Calkhoven, C.R.1    Muller, C.2    Leutz, A.3
  • 39
    • 38449122331 scopus 로고    scopus 로고
    • In vivo deletion analysis of the architecture of a multi-protein complex of translation initiation factors
    • Nielsen KH, Valášek L, (2007) In vivo deletion analysis of the architecture of a multi-protein complex of translation initiation factors. Methods Enzymol 431: 15-32.
    • (2007) Methods Enzymol , vol.431 , pp. 15-32
    • Nielsen, K.H.1    Valášek, L.2
  • 40
    • 0035865256 scopus 로고    scopus 로고
    • Related eIF3 subunits TIF32 and HCR1 interact with an RNA recoginition motif in PRT1 required for eIF3 integrity and ribosome binding
    • Valášek L, Phan L, Schoenfeld LW, Valášková V, Hinnebusch AG, (2001) Related eIF3 subunits TIF32 and HCR1 interact with an RNA recoginition motif in PRT1 required for eIF3 integrity and ribosome binding. EMBO J 20: 891-904.
    • (2001) EMBO J , vol.20 , pp. 891-904
    • Valášek, L.1    Phan, L.2    Schoenfeld, L.W.3    Valášková, V.4    Hinnebusch, A.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.