Concise synthesis and structure-activity relationship of furospinosulin-1, a hypoxia-selective growth inhibitor from marine sponge

Tetrahedron

Volumn 67, Issue 35, 2011, Pages 6673-6678

  Kotoku, Naoyuki ^a   Fujioka, Shinichi ^a   Nakata, Chiaki ^a   Yamada, Masaki ^a   Sumii, Yuji ^a   Kawachi, Takashi ^a   Arai, Masayoshi ^a   Kobayashi, Motomasa ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Analogue compound; Furospinosulin 1; Hypoxia selective growth inhibitor; Marine sponge

Indexed keywords

ANTINEOPLASTIC AGENT; FUROSPINOSULIN 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMICALS AND DRUGS; CONTROLLED STUDY; DACTYLOSPONGIA ELEGANS; DRUG ISOLATION; DRUG SYNTHESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPONGE (PORIFERA); STRUCTURE ACTIVITY RELATION;

EID: 79960936611     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2011.05.009     Document Type: Article

References (13)

1. M.W. Dewhirst, Y. Cao, and B. Moeller Nat. Rev. Cancer 8 2008 425
2. B.G. Wouters, and M. Koritzinsky Nat. Rev. Cancer 8 2008 851
3. G. Cimino, S. De Stefano, and L. Minale Tetrahedron 28 1972 1315
4. M. Arai, T. Kawachi, A. Setiawan, and M. Kobayashi ChemMedChem 5 2010 1919
5. C.V. Magatti, J.J. Kaminski, and I. Rothberg J. Org. Chem. 56 1991 3102
6. J.B. Sperry, and D.L. Wright Tetrahedron 62 2006 6551
7. S. Kaiser, S.P. Smidt, and A. Pfaltz Angew. Chem., Int. Ed. 45 2006 5194
8. P.A. Grieco, and Y. Masaki J. Org. Chem. 39 1974 2135
9. B. Robustell, I. Abe, and G.D. Prestwich Tetrahedron Lett. 39 1998 957
10. Y. Zheng, J. Lin, C. Li, and J. Li J. Chem. Res. 2007 686
11. M. Mohri, H. Kinoshita, K. Inomata, and H. Kotake Chem. Lett. 1985 451
12. A. Martins, and M. Lautens J. Org. Chem. 73 2008 8705
13. M.D. Morrison, J.J. Hanthorn, and D.A. Pratt Org. Lett. 11 2009 1051