Effects of inhibition of prostaglandin F 2α biosynthesis during preluteolysis and luteolysis in heifers

Theriogenology

Volumn 76, Issue 4, 2011, Pages 640-651

  Pugliesi, G ^a,b,c   Shrestha, H K ^a   Hannan, M A ^a   Carvalho, G R ^c   Beg, M A ^b   Ginther, O J ^a,b  

^a EUTHERIA FOUNDATION   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c FEDERAL UNIVERSITY OF VIÇOSA   (Brazil)

Author keywords

Heifers; LH; Luteolysis; PGFM pulses; Progesterone

Indexed keywords

15 KETO 13,14 DIHYDROPROSTAGLANDIN F2ALPHA; 15-KETO-13,14-DIHYDROPROSTAGLANDIN F2ALPHA; CLONIXIN; DRUG DERIVATIVE; FLUNIXIN MEGLUMINE; LUTEINIZING HORMONE; PROGESTERONE; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN RECEPTOR BLOCKING AGENT;

ANIMAL; ARTICLE; BIOSYNTHESIS; BLOOD; CATTLE; CHI SQUARE DISTRIBUTION; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; LUTEOLYSIS; METABOLISM; PHYSIOLOGY; RANDOMIZATION;

ANIMALS; CATTLE; CHI-SQUARE DISTRIBUTION; CLONIXIN; DINOPROST; FEMALE; LUTEINIZING HORMONE; LUTEOLYSIS; PROGESTERONE; PROSTAGLANDIN ANTAGONISTS; RANDOM ALLOCATION;

EID: 79960934937     PISSN: 0093691X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.theriogenology.2011.03.017     Document Type: Article

References (47)

1. McCracken J.A., Custer E.E., Lamsa J.C. Luteolysis: a neuroendocrine mediated event. Physiol Rev 1999, 79:263-323.
2. Skarzynski D.J., Ferreira-Dias G., Okuda K. Regulation of luteal function and corpus luteum regression in cows: hormonal control, immune mechanisms and intercellular communication. Reprod Dom Anim 2008, 43:57-65.
3. Kindahl H., Edqvist L.E., Granstrom E., Bane A. The release of prostaglandin F2 alpha as reflected by 15-keto-13,14-dihydroprostaglandin F2 alpha in the peripheral circulation during normal luteolysis in heifers. Prostaglandins 1976, 11:871-878.
4. Samuelsson B., Granstrom E., Green K., Hamberg M., Hammarstrom S. Prostaglandins. Ann Rev Biochem 1975, 44:669-695.
5. 2alpha, luteal blood flow, and luteolysis in cattle. Biol Reprod 2007, 76:506-513.
6. 2α for complete physiologic luteolysis in cattle. Biol Reprod 2009, 80:641-648.
7. 2α on reproductive hormones in mares. Theriogenology 2009, 72:417-424.
8. Schramm W., Bovaird L., Glew M.E., Schramm G., McCracken J.A. Corpus luteum regression induced by ultra-low pulses of prostaglandin F2 alpha. Prostaglandins 1983, 26:347-364.
9. Ginther O.J., Fuenzalida M.J., Shrestha H.K., Beg M.A. Concomitance of luteinizing hormone and progesterone oscillations during the transition from preluteolysis to luteolysis in cattle. Dom Anim Endocrinol 2010, 75:164-171.
10. Ginther O.J., Fuenzalida M.J., Pugliesi G., Hannan M.A., Beg M.A. Effect of luteinizing hormone oscillations on progesterone concentrations based on treatment with a gonadotropin-releasing hormone antagonist in heifers. Dom Anim Endocrinol 2011, 40:119-127.
11. Ginther O.J., Shrestha H.K., Fuenzalida M.J., Shahiduzzaman A.K., Hannan M.A., Beg M.A. Intrapulse temporality between pulses of a metabolite of prostaglandin F2α and circulating concentrations of progesterone before, during, and after spontaneous luteolysis in heifers. Theriogenology 2010, 74:1179-1186.
12. Ginther O.J., Shrestha H.K., Fuenzalida M.J., Shahiduzzaman A.K., Beg M.A. Characteristics of pulses of 13,14-dihydro-15-keto-prostaglandin F2alpha before, during, and after spontaneous luteolysis and temporal intrapulse relationships with progesterone concentrations in cattle. Biol Reprod 2010, 82:1049-1056.
13. Ginther O.J., Fuenzalida M.J., Shrestha H.K., Beg M.A. The transition between preluteolysis and luteolysis in cattle. Theriogenology 2011, 75:165-171.
14. Ginther O.J., Shrestha H.K., Fuenzalida M.J., Imam S., Beg M.A. Stimulation of pulses of 13,14-dihydro-15-keto-PGF2α (PGFM) with estradiol-17β and changes in circulating progesterone concentrations within a PGFM pulse in heifers. Theriogenology 2010, 74:384-392.
15. Imam S., Shrestha H.K., Beg M.A., Ginther O.J. Intrapulse changes in progesterone and LH concentrations and luteal blood flow during an estradiol-induced pulse of a metabolite of prostaglandin F2α in heifers. Anim Reprod Sci 2010, 121:34-38.
16. Shrestha H.K., Beg M.A., Imam S., Ginther O.J. Luteal blood flow and concentrations of circulating progesterone and other hormones associated with a simulated pulse of 13,14-dihydro-15-keto-prostaglandin F2α in heifers. Reproduction 2010, 139:673-683.
17. Shrestha H.K., Beg M.A., Siddiqui M.A., Ginther O.J. Dynamic progesterone responses to simulation of a natural pulse of a metabolite of prostaglandin F2α in heifers. Anim Reprod Sci 2010, 118:118-123.
18. Ginther O.J., Shrestha H.K., Beg M.A. Circulating concentrations within a pulse of a metabolite of prostaglandin F2α during preluteolysis and early luteolysis in heifers. Anim Reprod Sci 2010, 122:253-258.
19. 2+-dependent translocation domain with homology to PKC and GAP. Cell 1991, 65:1043-1051.
20. Smith W.L., Lands W.E. Oxygenation of polyunsaturated fatty acids during prostaglandin biosynthesis by sheep vesicular gland. Biochemistry 1972, 11:3276-3285.
21. Hamberg M., Svensson J., Samuelsson B. Prostaglandin endoperoxides. A new concept concerning the mode of action of prostaglandins. Proc Natl Acad Sci 1974, 71:3824-3828.
22. Simmons D.L., Botting R.M., Hla T. Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition. Pharmacol Rev 2004, 56:387-437.
23. Odensvik K., Gustafsson H., Kindahl H. The effect on luteolysis by intensive oral administration of flunixin granules in heifers. Anim Reprod Sci 1998, 50:35-44.
24. Tomlinson J.E., Wilder B.O., Young K.M., Blikslager A.T. Effects of flunixin meglumine or etodolac treatment on mucosal recovery of equine jejunum after ischemia. Am J Vet Res 2004, 65:761-769.
25. Aiumlamai S., Odensvik K., Stabenfeldt G., Kindahl H. Regulation of prostaglandin biosynthesis with flunixin meglumine in the bovine species. Zentralbl Veterinarmed A 1990, 37:16-22.
26. Guilbault L.A., Thatcher W.W., Drost M., Haibel G.K. Influence of physiological infusion of prostaglandin F2 alpha into postpartum cows with partially suppressed endogenous production of prostaglandin. 1. Uterine and ovarian morphological resposnses. Theriogenology 1987, 27:931-945.
27. Odensvik K., Gustafsson H. Effect of fluxixin during asynchronous embryo transfer in the heifer. Anim Reprod Sci 1994, 36:13-24.
28. Aké-Lopez R., Segura-Correa J.C., Quintal-Franco J. Effect of flunixin meglumine on the corpus luteum and possible prevention of embryonic loss in Pelibuey ewes. Small Ruminant Res 2005, 59:83-87.
29. Ginther O.J. Ultrasonic Imaging and Animal Reproduction: Book 3, Cattle 1998, Equiservices Publishing, Cross Plains, WI.
30. Araujo R.R., Ginther O.J., Ferreira J.C., Palhao M.M., Beg M.A., Wiltbank M.C. Role of follicular estradiol-17beta in timing of luteolysis in heifers. Biol Reprod 2009, 81:426-437.
31. 2α release episodes and oxytocin receptor development during luteolysis in the cow. Anim Reprod Sci 2006, 93:328-336.
32. Ginther O.J., Bergfelt D.R., Kulick L.J., Kot K. Pulsatility of systemic FSH and LH concentrations during follicular-wave development in cattle. Theriogenology 1998, 50:507-519.
33. Fitzgerald B.P., Affleck K.J., Barrows S.P., Murdoch W.L., Barker K.B., Loy R.G. Changes in LH pulse frequency and amplitude in intact mares during the transition into the breeding season. J Reprod Fertil 1987, 79:485-493.
34. Parkinson T.J., Lamming G.E. Interrelationships between progesterone, 13,14-dihydro-15-keto PGF-2 alpha (PGFM) and LH in cyclic and early pregnant cows. J Reprod Fertil 1990, 90:22133.
35. Ginther O.J., Fuenzalida M.J., Hannan M.A., Beg M.A. Pulsatility and interrelationship of 13,14-dihydro-15-keto-PGF2 alpha (PGFM), luteinizing hormone, progesterone, and estradiol in heifers. Biol Reprod 2011, 10.1095/biolreprod.110.089953.
36. Palhao M.P., Beg M.A., Rodrigues M.T., Ginther O.J. Follicle and hormone dynamics in single versus double ovulating heifers. Reproduction 2009, 138:561-570.
37. Hannan M.A., Fuenzalida M.J., Siddiqui M.A., Shamsuddin M., Beg M.A., Ginther O.J. Diurnal variation in LH and temporal relationships between oscillations in LH and progesterone during the luteal phase in heifers. Theriogenology 2010, 74:1491-1498.
38. Godkin J.D., Roberts M.P., Elgayyar M., Guan W., Tithof P.K. Phospholipase A2 regulation of bovine endomentrial (BEND) cell prostaglandin production. Reprod Biol Endocrinol 2008, 6:44.
39. 2α production in CL. Mol Cell Endocrinol 2002, 191:65-80.
40. 2α during luteolysis in ruminants. Biol Reprod 1991, 45:655-663.
41. Barrata M., Grasselli F., Tamanini C. Effects of gonodal steroids on tonic luteinizing hormone (LH) release and luteinizing hormone-releasing hormone-induced LH release from bovine pituitary cells cultured in vitro. Biol Reprod 1994, 50:1320-1327.
42. 2α in the conscious non-pregnant cow. J Physiol 1985, 358:107-118.
43. Shemesh M., Mizrachi D., Gurevich M., Shore L.S., Reed J., Chang S.-M.T., Thatcher W.W., Fields M.J. Expression of functional luteinizing hormone (LH) receptor and its messenger ribonucleic acid in bovine endometrium: LH augmentation of cAMP and inositol phosphate in vitro and human chorionic gonadotropin (hCG) augmentation of peripheral prostaglandin in vivo. Reprod Biol 2001, 1:13-32.
44. Fields M.J., Shemesh M. Extragonadal luteinizing hormone receptors in the reproductive tract of domestic animals. Biol Reprod 2004, 71:1412-1418.
45. Wiltbank M.C., Belfiore C.J., Niswender G.D. Steroidogenic enzyme activity after acute activation of protein kinase (PK) A and PKC in ovine small and large cells. Mol Cell Endocrinol 1993, 97:1-7.
46. 2α. Biol Reprod 1990, 42:239-245.
47. 2α based on serial biopsies in vivo. Reproduction 2001, 121:905-913.