Phosphopeptides with improved cellular uptake properties as ligands for the polo-box domain of polo-like kinase 1

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 16, 2011, Pages 4686-4689

  Richter, Susan ^a   Neundorf, Ines ^b   Loebner, Kristin ^b   Gräber, Martin ^b   Berg, Thorsten ^b   Bergmann, Ralf ^a   Steinbach, Joerg ^a   Pietzsch, Jens ^a   Wuest, Frank ^c  

^a INSTITUTE OF ION BEAM PHYSICS AND MATERIALS RESEARCH   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Cell penetrating peptides; Cellular uptake; Phosphopeptides; Polo box domain; Polo like kinase 1

Indexed keywords

ANTINEOPLASTIC AGENT; CELL PENETRATING PEPTIDE; CELL PENETRATING PEPTIDE SC18; CELL PENETRATING PEPTIDE SC18 MQSPTPL CONJUGATE; DIMER; EPITOPE; HUMAN CALCITONIN [18-32] MQSPTPL CONJUGATE; HUMAN CALCITONIN DERIVED PEPTIDE; LIGAND; PHOSPHOEPITOPE; PHOSPHOPEPTIDE; POLO LIKE KINASE 1; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BREAST ADENOCARCINOMA; CANCER CELL CULTURE; CELL TRANSPORT; COLORECTAL CARCINOMA; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; ISOTOPE LABELING; MOLECULAR PROBE; PROTEIN DOMAIN; PROTEIN MOTIF; UTERINE CERVIX CARCINOMA;

ANTINEOPLASTIC AGENTS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HELA CELLS; HUMANS; LIGANDS; PHOSPHOPEPTIDES; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TISSUE DISTRIBUTION;

EID: 79960920293     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.06.103     Document Type: Article

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