Adverse effects in wild fish living downstream from pharmaceutical manufacture discharges

Environment International

Volumn 37, Issue 8, 2011, Pages 1342-1348

  Sanchez, Wilfried ^a   Sremski, William ^b   Piccini, Benjamin ^a   Palluel, Olivier ^a   Maillot Maréchal, Emmanuelle ^a   Betoulle, Stéphane ^c   Jaffal, Ali ^c   Aït Aïssa, Sélim ^a   Brion, François ^a   Thybaud, Eric ^a   Hinfray, Nathalie ^a   Porcher, Jean Marc ^a  

^a INSTITUT NATIONAL DE L ENVIRONNEMENT INDUSTRIEL ET DES RISQUES INERIS   (France)

^b Office National de l'Eau et des Milieux Aquatiques (ONEMA)   (France)

^c UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

Author keywords

Biomarkers; Endocrine disruption; Gudgeon; Pharmaceutical

Indexed keywords

BIOMARKERS; DRUG PRODUCTS; EFFLUENTS; ENDOCRINE DISRUPTERS; FISHERIES; MANUFACTURE; RIVER POLLUTION; SEWAGE; TOXICITY;

BIOTRANSFORMATION ENZYMES; ENDOCRINE DISRUPTION; FISH POPULATIONS; GUDGEON; INDUSTRIAL EFFLUENT; MONITORING APPROACH; PHARMACEUTICAL COMPOUNDS; PHARMACEUTICAL MANUFACTURE;

FISH;

ACETYLCHOLINESTERASE; BIOLOGICAL MARKER; CYTOCHROME P450 3A; ETHOXYRESORUFIN DEETHYLASE; GLUTATHIONE TRANSFERASE; LYSOZYME; VITELLOGENIN;

BIOMARKER; DISCHARGE; EFFLUENT; ENDOCRINE DISRUPTOR; FISH; INDUSTRIAL WASTE; MANUFACTURING; PHARMACEUTICAL INDUSTRY; POLLUTION EFFECT; POPULATION DYNAMICS; WILD POPULATION;

ABDOMINAL SWELLING; ADVERSE OUTCOME; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; BIOTRANSFORMATION; BLEEDING; CONTROLLED STUDY; EFFLUENT TOXICITY; ENDOCRINE DISEASE; FISH; GONAD DYSFUNCTION; HISTOPATHOLOGY; NEUROTOXICITY; NONHUMAN; POLLUTION MONITORING; POPULATION DENSITY; PRIORITY JOURNAL; SEWAGE EFFLUENT; SEX RATIO; STREAM (RIVER); WATER ANALYSIS; WATER CONTAMINATION; WILD ANIMAL;

GOBIO;

EID: 79960919683     PISSN: 01604120     EISSN: 18736750     Source Type: Journal    
DOI: 10.1016/j.envint.2011.06.002     Document Type: Article

References (52)

1. An W., Hu J., Giesy J.P., Yang M. Extinction risk of exploited wild roach (Rutilus rutilus) populations due to chemical feminization. Environ Sci Technol 2009, 43:7895-7901.
2. Blazer V.S. Histopathological assessment of gonadal tissue in wild fishes. Fish Physiol Biochem 2002, 26:85-101.
3. Bradford M.M. A rapid sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:248-254.
4. Brion F., Rogerieux F., Noury P., Migeon B., Flammarion P., Thybaud E., et al. Two step purification method of vitellogenin from three teleost fish species: rainbow trout (Oncorhynchus mychiss), gudgeon (Gobio gobio) and chub (Leuciscus cephalus). J Chroma B 2000, 737:3-12.
5. Brown K.D., Kulis J., Thomson B., Chapman T.H., Mawhinney D.B. Occurrence of antibiotics in hospital, residential, and dairy effluent, municipal wastewater, and the Rio Grande in New Mexico. Sci Total Environ 2006, 366:772-783.
6. Ellman G.L., Courtney K.D., Andres V., Featherstone R.M. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 1961, 7:88-95.
7. Escher B.I., Baumgartner R., Koller M., Treyer K., Lienert J., McArdell C.S. Environmental toxicology and risk assessment of pharmaceuticals from hospital wastewater. Water Res 2011, 45:75-92.
8. Faller P., Kobler B., Peter A., Sumpter J.P., Burkhardt-Holm P. Stress status of gudgeon (Gobio gobio) from rivers in switzerland with and without input of sewage treatment plant effluent. Environ Toxicol Chem 2003, 22:2063-2072.
9. Fent K., Weston A.A., Caminada D. Ecotoxicology of human pharmaceuticals. Aquat Toxicol 2006, 76:122-159.
10. Flammarion P., Migeon B., Garric J. Statistical analysis of cyprinid ethoxyresorufin-o-deethylase data in a large French watershed. Ecotoxicol Environ Saf 1998, 40:144-153.
11. Gagne F., Blaise C. Effects of pharmaceuticals on aquatic biota - a review. Curr Top Toxicol 2004, 1:73-86.
12. Habig W.H., Pabst M.J., Jakoby W.B. Glutathione s-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem 1974, 249:7130-7139.
13. Halling-Sørensen B., Nors Nielsen S., Lanzky P.F., Ingerslev F., Holten Lützhøft H.C., Jørgensen S.E. Occurrence, fate and effects of pharmaceutical substances in the environment - a review. Chemosphere 1998, 36:357-393.
14. Hanson N., Aberg P., Sundelof A. Population-level effects of male-biased broods in eelpout (Zoarces viviparus). Environ Toxicol Chem 2005, 24:1235-1241.
15. Harris C.A., Hamilton P.B., Runnalls T.J., Vinciotti V., Henshaw A., Hodgson D., et al. The consequences of feminization in breeding groups of male fish. Environ Health Perspect 2011, 119:306-311.
16. Hattori R.S., Fernandino J.I., Kishii A., Kimura H., Kinno T., Oura M., et al. Cortisol-induced masculinization: does thermal stress affect gonadal fate in pejerrey, a teleost fish with temperature-dependent sex determination?. PLoS One 2009, 4:e6548. 10.1371/journal.pone.0006548.
17. Heincke F. Bericht über die Untersuchungen der Biologischen Anstalt auf Helgoland zur Naturgeschichte der Nutzfische. Die Beteiligung Deutschlands an der Internationalen Meeresforschung 1908, 4/5:67-155.
18. Hinfray N., Palluel O., Piccini B., Sanchez W., Aït-Aïssa S., Noury P., et al. Endocrine disruption in wild populations of chub (Leuciscus cephalus) in contaminated French streams. Sci Total Environ 2010, 408:2146-2154.
19. Howell W.L., Hunsinger R.N., Blanchard P.D. Paradoxical masculinization of female Western Mosquitofish during exposure to spironolactone. Prog Fish Culturist 1994, 56:51-55.
20. Huet M. Aperçu des relations entre la pente et les populations piscicoles des eaux courantes. Schweizerische Zeitschrift für Hydrologie 1949, I1:332-351.
21. Jobling S., Nolan M., Tyler C.R., Brighty G., Sumpter J.P. Widespread sexual disruption in wild fish. Environ Sci Technol 1998, 32:2498-2506.
22. Jobling S., Beresford N., Nolan M., Rodgers-Gray T., Brighty G.C., Sumpter J.P., et al. Altered sexual maturation and gamete production in wild roach (Rutilus rutilus) living in rivers that receive treated sewage effluents. Biol Reprod 2002, 66:272-281.
23. Jobling S., Coey S., Whitmore J.G., Kime D.E., Van Look K.J.W., McAllister B.G., et al. Wild intersex roach (Rutilus rutilus) have reduced fertility. Biol Reprod 2002, 67:515-524.
24. Kelly J.M., Janz D.M. Assessment of oxidative stress and histopathology in juvenile northern pike (Esox lucius) inhabiting lakes downstream of a uranium mill. Aquat Toxicol 2009, 92:240-249.
25. Kestemont P. Etude du cycle reproducteur du goujon, Gobio gobio L. 1. Variations saisonnières dans l'histologie de l'ovaire. J Appl Ichthyol 1987, 3:145-157.
26. Kidd K.A., Blanchfield P.J., Mills K.H., Palace V.P., Evans R.E., Lazorchak J.M., et al. Collapse of a fish population after exposure to a synthetic estrogen. P Natl Aca Sci USA 2007, 104:8897-8901.
27. Kümmerer K. Drugs in the environment: emission of drugs, diagnostic aids and disinfectants into wastewater by hospitals in relation to other sources - a review. Chemosphere 2001, 45:957-969.
28. Kümmerer K. The presence of pharmaceuticals in the environment due to human use - present knowledge and future challenges. J Environ Manage 2009, 90:2354-2366.
29. Labadie P., Budzinski H. Determination of steroidal hormone profiles along the Jalle d'Eysines river (near Bordeaux, France). Environ Sci Technol 2005, 39:5113-5120.
30. Larsson D.G.J., Förlin L. Male-biased sex ratios of fish embryos near a pulp mill: temporary recovery after a short-term shutdown. Environ Health Persp 2002, 110:739-742.
31. Larsson D.G.J., de Pedro C., Paxeus N. Effluent from drug manufactures contains extremely high levels of pharmaceuticals. J Hazard Mater 2007, 148:751-755.
32. Matamoros V., Arias C., Brix H., Bayona J.M. Preliminary screening of small-scale domestic wastewater treatment systems for removal of pharmaceutical and personal care products. Water Res 2009, 43:55-62.
33. Laville N., Aït-Aïssa S., Gomez E., Casellas C., Porcher J.M. Effects of human pharmaceuticals on cytotoxicity, EROD activity and ROS production in fish hepatocytes. Toxicology 2004, 196:41-55.
34. Miller V.P., Stresser D.M., Blanchard A.P., Turner S., Crespi C.L. Fluorimetric high-throughput screening for inhibitors of cytochrome P450. Ann NY Aca Sci 2000, 919:26-32.
35. Minier C., Caltot G., Leboulanger F., Hill E.M. An investigation of the incidence of intersex fish in Seine-Maritime and Sussex regions. Analusis 2000, 28:801-806.
36. Mimeault C., Woodhouse A.J., Miao X.S., Metcalfe C.D., Moon T.W., Trudeau V.L. The human lipid regulator, gemfibrozil bioconcentrates and reduces testosterone in the goldfish, Carassius auratus. Aquat Toxicol 2005, 73:44-54.
37. Nash J.P., Kime D.E., Van der Ven L.T.M., Wester P.W., Brion F., Maack G., et al. Long-term exposure to environmental concentrations of the pharmaceutical ethynylestradiol causes reproductive failure in fish. Environ Health Persp 2004, 112:1725-1733.
38. Olivares A., Quirós L., Pelayo S., Navarro A., Bosch C., Grimalt J.O., et al. Integrated biological and chemical analysis of organochlorine compound pollution and of its biological effects in a riverine system downstream the discharge point. Sci Total Environ 2010, 408:5592-5599.
39. Pagano G., de Biase A., Deeva I.B., Degan P., Doronin Y.K., Iaccarino M., et al. The role of oxidative stress in developmental and reproductive toxicity of tamoxifen. Life Sci 2001, 68:1735-1749.
40. Paulos P., Runnalls T.J., Nallani G., La Point T., Scott A.P., Sumpter J.P., et al. Reproductive responses in fathead minnow and Japanese medaka following exposure to a synthetic progestin, Norethindrone. Aquat Toxicol 2010, 99:256-262.
41. Phillips P.J., Smith S.G., Kolpin D.W., Zaugg S.D., Buxton H.T., Furlong E.T., et al. Pharmaceutical formulation facilities as sources of opioids and other pharmaceuticals to wastewater treatment plant effluents. Environ Sci Technol 2010, 44:4910-4916.
42. Rabiet M., Togola A., Brissaud F., Seidel J.L., Budzinski H., Elbaz-Poulichet F. Consequences of treated water recycling as regards pharmaceuticals and drugs in surface and ground waters of a medium-sized Mediterranean catchment. Environ Sci Technol 2006, 40:5282-5288.
43. Sanchez W., Porcher J.M. Fish biomarkers for environmental monitoring within the Water framework Directive of the European Union. TRAC-Trend Anal Chem 2009, 28:150-158.
44. Sanchez W., Piccini B., Maillot-Maréchal E., Porcher J.M. Comparison of two reference systems for biomarker data analysis in a freshwater biomonitoring context. Environ Int 2010, 36:377-382.
45. Santos J.L., Aparicio I., Callejón M., Alonso E. Occurrence of pharmaceutically active compounds during 1-year period in wastewaters from four wastewater treatment plants in Seville (Spain). J Hazard Mater 2009, 164:1509-1516.
46. Sim W.J., Lee J.W., Lee E.S., Shin S.K., Hwang S.R., Oh J.E. Occurrence and distribution of pharmaceuticals in wastewater from households, livestock farms, hospitals and pharmaceutical manufactures. Chemosphere 2011, 82:179-186.
47. Studnicka M., Siwicki A., Ryka B. Lysozyme level in carp (Cyprinus carpio L.). Bamidgeh 1986, 1:22-25.
48. Tamtam F., Mercier F., Le Bot B., Eurin J., Tuc Dinh Q., Clément M., et al. Occurrence and fate of antibiotics in the Seine River in various hydrological conditions. Sci Total Environ 2008, 393:84-95.
49. Togola A., Budzinski H. Multi-residue analysis of pharmaceutical compounds in aqueous samples. J Chrom A 2008, 1177:150-158.
50. van Aerle R., Nolan M., Jobling S., Christiansen L.B., Sumpter J.P., Tyler C.R. Sexual disruption in a second species of wild cyprinid fish (the gudgeon, Gobio gobio) in United Kingdom freshwaters. Environ Toxicol Chem 2001, 20:2841-2847.
51. Yu-Chen Lin A., Tsai Y.T. Occurrence of pharmaceuticals in Taiwan's surface waters: impact of waste streams from hospitals and pharmaceutical production facilities. Sci Total Environ 2009, 407:3793-3802.
52. Zeilinger J., Steger-Hartmann T., Maser E., Goller S., Vonk R., Lange R. Effects of synthetic gestagens on fish reproduction. Environ Toxicol Chem 2009, 28:2663-2670.