Preparation of micronized β-HMX using supercritical carbon dioxide as antisolvent

Industrial and Engineering Chemistry Research

Volumn 50, Issue 15, 2011, Pages 9107-9115

  Lee, Byoung Min ^a   Kim, Soo Jung ^a   Lee, Byung Chul ^b   Kim, Hyoun Soo ^c   Kim, Hwayong ^a   Lee, Youn Woo ^a  

^a Seoul National University   (South Korea)

^b Hannam University   (South Korea)

^c Agency for Defence Development   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AEROSOL SOLVENT EXTRACTION SYSTEMS; AGITATION SPEED; ANTI-SOLVENTS; CRYSTAL PHASIS; FEEDING RATE; FIELD EMISSION SCANNING ELECTRON MICROSCOPY; FOURIER TRANSFORM INFRARED; GAS ANTI-SOLVENT PROCESS; MICRONIZATIONS; SUPERCRITICAL CARBON DIOXIDES;

ACETONE; CARBON DIOXIDE; ENAMELS; EXTRACTION; FOURIER TRANSFORMS; GASES; ORGANIC SOLVENTS; PARTICLE SIZE; RECRYSTALLIZATION (METALLURGY); SCANNING ELECTRON MICROSCOPY; SIZE DISTRIBUTION; SOLVENTS; SUPERCRITICAL FLUID EXTRACTION;

PARTICLE SIZE ANALYSIS;

EID: 79960874371     PISSN: 08885885     EISSN: 15205045     Source Type: Journal    
DOI: 10.1021/ie102593p     Document Type: Article

References (20)

1. Van der Steen, A.; Verbeek, R. Initiation and Detonation of RDX and HMX HTPB-based Plastic-Bonded Explosives Propellants, Explos., Pyrotech. 1990, 15, 19
2. Jung, J.; Perrut, M. Particle Design Using Supercritical Fluids: Literature and Patent Survey J. Supercrit. Fluids 2001, 20, 179
3. Shariati, A.; Peters, C. J. Recent Developments in Particle Design Using Supercritical Fluids Curr. Opin. Solid State Mater. Sci. 2003, 7, 371
4. Reverchon, E.; De Marco, I.; Torino, E. Nanoparticles Production by Supercritical Antisolvent Precipitation: A General Interpretation J. Supercrit. Fluids 2007, 43, 126
5. Chu, J.; Li, G.; Row, K. H.; Kim, H.; Lee, Y.-W. Preparation of Cefpodoxime Proxetil Fine Particles Using Supercritical Fluids Int. J. Pharm. 2009, 369, 85
6. Thiering, R.; Dehghani, F.; Foster, N. R. Current Issues Relating to Anti-Solvent Micronisation Techniques and Their Extension to Industrial Scales J. Supercrit. Fluids 2001, 21, 159
7. Adami, R.; Osséo, L. S.; Huopalahti, R.; Reverchon, E. Supercritical AntiSolvent Micronization of PVA by Semi-Continuous and Batch Processing J. Supercrit. Fluids 2007, 42, 288
8. Steckel, H.; Thies, J.; Müller, B. W. Micronizing of Steroids for Pulmonary Delivery by Supercritical Carbon Dioxide Int. J. Pharm. 1997, 152, 99
9. Gallagher-Wetmore, P.; Coffey, M. P.; Krukonis, V. Application of Supercritical Fluids in Recrystallization: Nucleation and Gas Anti-Solvent (GAS) Techniques Respir. Drug Delivery 1994, 4, 287
10. 2 Antisolvent Recrystallization Chin. J. Chem. Eng. 2001, 9, 258
11. Teipel, U.; Förter-Barth, U.; Krause, H. H. Crystallization of HMX Particles by Using the Gas Anti-Solvent Process Propellants, Explos., Pyrotech. 1999, 24, 195
12. Svensson, L.; Nyqvist, J. O.; Westling, L. Crystallization of HMX from γ-Butyrolactone J. Hazard. Mater. 1986, 13, 103
13. Lee, B. M.; Jeong, J. S.; Lee, Y. H.; Lee, B. C.; Kim, H. S.; Kim, H.; Lee, Y.-W. Supercritical Antisolvent Micronization of Cyclotrimethylenetrinitramin: Influence of the Organic Solvent Ind. Eng. Chem. Res. 2009, 48, 11162
14. Warwick, B.; Dehghani, F.; Foster, N. R.; Biffin, J. R.; Regtop, H. L. Micronization of Copper Indomethacin Using Gas Antisolvent Processes Ind. Eng. Chem. Res. 2002, 41, 1993
15. Achuthan, C. P.; Jose, C. I. Studies on Octahydro-1,3,5,7-tetranitro-1,3, 5,7-tetrazocine (HMX) Polymorphism Propellants, Explos., Pyrotech. 1990, 15, 271
16. Gallagher, P. M.; Coffey, M. P.; Krukonis, V. J.; Hillstrom, W. W. Gas Anti-Solvent Recrystallization of RDX: Formation of Ultra-Fine Particles of a Difficult-to-Comminute Explosive J. Supercrit. Fluids 1992, 5, 130
17. Kordikowski, A.; Schenk, A. P.; Van Nielen, R. M.; Peters, C. J. Volume Expansions and Vapor-Liquid Equilibria of Binary Mixtures of a Variety of Polar Solvents and Certain Near-Critical Solvents J. Supercrit. Fluids 1995, 8, 205
18. Müller, M.; Meier, U.; Kessler, A.; Mazzotti, M. Experimental Study of the Effect of Process Parameters in the Recrystallization of an Organic Compound Using Compressed Carbon Dioxide as Antisolvent Ind. Eng. Chem. Res. 2000, 39, 2260
19. Bakhbakhi, Y.; Charpentier, P. A.; Rohani, S. Experimental Study of the GAS Process for Producing Microparticles of Beclomethasone-17,21-dipropionate Suitable for Pulmonary Delivery Int. J. Pharm. 2006, 309, 71
20. Bakhbakhi, Y.; Rohani, S.; Charpentier, P. A. Micronization of Phenanthrene Using the Gas Antisolvent Process. 1. Experimental Study and Use of FTIR Ind. Eng. Chem. Res. 2005, 44, 7337