The neural basis of familial risk and temperamental variation in individuals at high risk of bipolar disorder

Biological Psychiatry

Volumn 70, Issue 4, 2011, Pages 343-349

  Whalley, Heather C ^a   Sussmann, Jessika E ^a   Chakirova, Goultchira ^a   Mukerjee, Prerona ^a   Peel, Anna ^a   McKirdy, James ^a   Hall, Jeremy ^a   Johnstone, Eve C ^a   Lawrie, Stephen M ^a   McIntosh, Andrew M ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Amygdala; bipolar disorder; fMRI; prefrontal; striatum

Indexed keywords

ADULT; AMYGDALOID NUCLEUS; ARTICLE; BIPOLAR DISORDER; BRAIN REGION; CONTROLLED STUDY; CORPUS STRIATUM; CYCLOTHYMIA; FAMILY ASSESSMENT; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HAMILTON SCALE; HIGH RISK POPULATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PREFRONTAL CORTEX; PRIORITY JOURNAL; TEMPERAMENT; YOUNG MANIA RATING SCALE;

ADOLESCENT; ADULT; BIPOLAR DISORDER; BRAIN MAPPING; ECHO-PLANAR IMAGING; FAMILY HEALTH; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; PERSONALITY INVENTORY; PSYCHIATRIC STATUS RATING SCALES; REGRESSION ANALYSIS; RISK FACTORS; TEMPERAMENT; YOUNG ADULT;

EID: 79960841930     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2011.04.007     Document Type: Article

References (46)

1. M.L. Phillips, W.C. Drevets, S.L. Rauch, and R. Lane Neurobiology of emotion perception, II: Implications for major psychiatric disorders Biol Psychiatry 54 2003 515 528 (Pubitemid 37289438)
2. S.M. Strakowski, M.P. Delbello, and C.M. Adler The functional neuroanatomy of bipolar disorder: A review of neuroimaging findings Mol Psychiatry 10 2005 105 116 (Pubitemid 40139591)
3. F.Y. Womer, J.H. Kalmar, F. Wang, and H.P. Blumberg A ventral prefrontal-amygdala neural system in bipolar disorder: A view from neuroimaging research Acta Neuropsychiatrica 21 2009 228 238
4. M.L. Phillips, and E. Vieta Identifying functional neuroimaging biomarkers of bipolar disorder: Toward DSM-V Schizophr Bull 33 2007 893 904 (Pubitemid 47216661)
5. B. Arts, J. Jabben, L. Krabbendam, and J. van Os Meta-analyses of cognitive functioning in euthymic bipolar patients and their first-degree relatives Psychol Med 38 2008 771 785 (Pubitemid 351684591)
6. T. Dixon, E. Kravariti, C. Frith, R.M. Murray, and P.K. McGuire Effect of symptoms on executive function in bipolar illness Psychol Med 34 2004 811 821 (Pubitemid 39089520)
7. A.M. McIntosh, H.C. Whalley, J. McKirdy, J. Hall, J.E. Sussmann, and P. Shankar Prefrontal function and activation in bipolar disorder and schizophrenia Am J Psychiatry 165 2008 378 384 (Pubitemid 351704494)
8. V.A. Curtis, J.M. Thompson, M.L. Seal, P.J. Monks, A.J. Lloyd, and L. Harrison The nature of abnormal language processing in euthymic bipolar I disorder: Evidence for a relationship between task demand and prefrontal function Bipolar Disord 9 2007 358 369 (Pubitemid 46865368)
9. V.A. Curtis, T.A. Dixon, R.G. Morris, E.T. Bullmore, M.J. Brammer, and S.C. Williams Differential frontal activation in schizophrenia and bipolar illness during verbal fluency J Affect Disord 66 2001 111 121 (Pubitemid 32907516)
10. M.P. Allin, N. Marshall, K. Schulze, M. Walshe, M.H. Hall, and M. Picchioni A functional MRI study of verbal fluency in adults with bipolar disorder and their unaffected relatives Psychol Med 40 2010 2025 2035
11. M.L. Phillips, C.D. Ladouceur, and W.C. Drevets A neural model of voluntary and automatic emotion regulation: Implications for understanding the pathophysiology and neurodevelopment of bipolar disorder Mol Psychiatry 13 2008 829
12. M.A. Cerullo, C.M. Adler, M.P. Delbello, and S.M. Strakowski The functional neuroanatomy of bipolar disorder Int Rev Psychiatry 21 2009 314 322
13. O. Gruber, H. Tost, I. Henseler, C. Schmael, H. Scherk, and G. Ende Pathological amygdala activation during working memory performance: Evidence for a pathophysiological trait marker in bipolar affective disorder Hum Brain Mapp 31 2010 115 125
14. P. McGuffin, F. Rijsdijk, M. Andrew, P. Sham, R. Katz, and A. Cardno The heritability of bipolar affective disorder and the genetic relationship to unipolar depression Arch Gen Psychiatry 60 2003 497 502 (Pubitemid 36539059)
15. A.M. McIntosh, D.E. Job, W.J. Moorhead, L.K. Harrison, H.C. Whalley, and E.C. Johnstone Genetic liability to schizophrenia or bipolar disorder and its relationship to brain structure Am J Med Genet B Neuropsychiatr Genet 141 2006 76 83 (Pubitemid 43062547)
16. A.M. McIntosh, D.E. Job, T.W. Moorhead, L.K. Harrison, S.M. Lawrie, and E.C. Johnstone White matter density in patients with schizophrenia, bipolar disorder and their unaffected relatives Biol Psychiatry 58 2005 254 257 (Pubitemid 41112275)
17. A.M. McIntosh, D.E. Job, T.W. Moorhead, L.K. Harrison, K. Forrester, and S.M. Lawrie Voxel-based morphometry of patients with schizophrenia or bipolar disorder and their unaffected relatives Biol Psychiatry 56 2004 544 552 (Pubitemid 39336401)
18. C. McDonald, N. Marshall, P.C. Sham, E.T. Bullmore, K. Schulze, and B. Chapple Regional brain morphometry in patients with schizophrenia or bipolar disorder and their unaffected relatives Am J Psychiatry 163 2006 478 487 (Pubitemid 44469391)
19. T. Hajek, E. Gunde, C. Slaney, L. Propper, G. MacQueen, and A. Duffy Striatal volumes in affected and unaffected relatives of bipolar patientsHigh-risk study J Psychiatr Res 43 2009 724 729
20. C.A. Chaddock, G.J. Barker, N. Marshall, K. Schulze, M.H. Hall, and A. Fern White matter microstructural impairments and genetic liability to familial bipolar I disorder Br J Psychiatry 194 2009 527 534
21. J.A. Frazier, J.L. Breeze, G. Papadimitriou, D.N. Kennedy, S.M. Hodge, and C.M. Moore White matter abnormalities in children with and at risk for bipolar disorder Bipolar Disord 9 2007 799 809 (Pubitemid 350215105)
22. D. Drapier, S. Surguladze, N. Marshall, K. Schulze, A. Fern, and M.H. Hall Genetic liability for bipolar disorder is characterized by excess frontal activation in response to a working memory task Biol Psychiatry 64 2008 513 520
23. H.W. Thermenos, J.M. Goldstein, S.M. Milanovic, S. Whitfield-Gabrieli, N. Makris, and P. Laviolette An fMRI study of working memory in persons with bipolar disorder or at genetic risk for bipolar disorder Am J Med Genet B Neuropsychiatr Genet 153B 2009 120 131
24. L. Evans, H.S. Akiskal, P.E. Keck Jr, S.L. McElroy, A.D. Sadovnick, and R.A. Remick Familiality of temperament in bipolar disorder: Support for a genetic spectrum J Affect Disord 85 2005 153 168 (Pubitemid 40386536)
25. H.S. Akiskal, M.V. Mendlowicz, G. Jean-Louis, M.H. Rapaport, J.R. Kelsoe, and J.C. Gillin TEMPS-A: Validation of a short version of a self-rated instrument designed to measure variations in temperament J Affect Disord 85 2005 45 52 (Pubitemid 40386525)
26. M.V. Mendlowicz, G. Jean-Louis, J.R. Kelsoe, and H.S. Akiskal A comparison of recovered bipolar patients, healthy relatives of bipolar probands, and normal controls using the short TEMPS-A J Affect Disord 85 2005 147 151 (Pubitemid 40386535)
27. P. Chiaroni, E.G. Hantouche, J. Gouvernet, J.M. Azorin, and H.S. Akiskal The cyclothymic temperament in healthy controls and familially at risk individuals for mood disorder: Endophenotype for genetic studies? J Affect Disord 85 2005 135 145 (Pubitemid 40386534)
28. P. McGuffin, A. Farmer, and I. Harvey A polydiagnostic application of operational criteria in studies of psychotic illness Development and reliability of the OPCRIT system Arch Gen Psychiatry 48 1991 764 770
29. R.C. Young, J.T. Biggs, V.E. Ziegler, and D.A. Meyer A rating scale for mania: Reliability, validity and sensitivity Br J Psychiatry 133 1978 429 435 (Pubitemid 9006756)
30. M. Hamilton A rating scale for depression J Neurol Neurosurg Psychiatry 23 1960 56 62
31. P. Burgess, and T. Shallice The Hayling and Brixton Tests 1997 Thames Valley Test Company Limited Bury St. Edmunds, United Kingdom
32. H.C. Whalley, E. Simonotto, S. Flett, I. Marshall, K.P. Ebmeier, and D.G. Owens fMRI correlates of state and trait effects in subjects at genetically enhanced risk of schizophrenia [see comment] Brain 127 2004 478 490 (Pubitemid 38295466)
33. P.A. Bloom, and I. Fischler Completion norms for 329 sentence contexts Mem Cogn 8 1980 631 642
34. J.A. Maldjian, P.J. Laurienti, R.A. Kraft, and J.H. Burdette An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets Neuroimage 19 2003 1233 1239 (Pubitemid 36918259)
35. N. Tzourio-Mazoyer, B. Landeau, D. Papathanassiou, F. Crivello, O. Etard, and N. Delcroix Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain Neuroimage 15 2002 273 289 (Pubitemid 34852226)
36. E.A. Phelps, and J.E. LeDoux Contributions of the amygdala to emotion processing: From animal models to human behavior Neuron 48 2005 175 187 (Pubitemid 41476352)
37. J.E. LeDoux Emotion circuits in the brain Annu Rev Neurosci 23 2000 155 184
38. R. Adolphs, L. Cahill, R. Schul, and R. Babinsky Impaired declarative memory for emotional material following bilateral amygdala damage in humans Learn Mem 4 1997 291 300 (Pubitemid 27500542)
39. H.P. Blumberg, A. Martin, J. Kaufman, H.C. Leung, P. Skudlarski, and C.M. Lacadie Frontostriatal abnormalities in adolescents with bipolar disorder: Preliminary observations from functional MRI Am J Psychiatry 160 2003 1345 1347 (Pubitemid 41070956)
40. Tijssen MJ, Van Os J, Wittchen HU, Lieb R, Beesdo K, Wichers M: Risk factors predicting onset and persistence of subthreshold expression of bipolar psychopathology among youth from the community. Acta Psychiatr Scand 122:255266.
41. J.O. Brooks 3rd, J.C. Hoblyn, S.A. Woodard, A.C. Rosen, and T.A. Ketter Corticolimbic metabolic dysregulation in euthymic older adults with bipolar disorder J Psychiatr Res 43 2009 497 502
42. A.M. McIntosh, S. Munoz Maniega, G.K. Lymer, J. McKirdy, J. Hall, and J.E. Sussmann White matter tractography in bipolar disorder and schizophrenia Biol Psychiatry 64 2008 1088 1092
43. F. Wang, J.H. Kalmar, Y. He, M. Jackowski, L.G. Chepenik, and E.E. Edmiston Functional and structural connectivity between the perigenual anterior cingulate and amygdala in bipolar disorder Biol Psychiatry 66 2009 516 521
44. J.E. Sussmann, G.K. Lymer, J. McKirdy, T.W. Moorhead, S. Munoz Maniega, and D. Job White matter abnormalities in bipolar disorder and schizophrenia detected using diffusion tensor magnetic resonance imaging Bipolar Disord 11 2009 11 18
45. Benedetti F, Yeh PH, Bellani M, Radaelli D, Nicoletti MA, Poletti S, et al. Disruption of white matter integrity in bipolar depression as a possible structural marker of illness. Biol Psychiatry 69:309317.
46. E. Sprooten, J.E. Sussmann, A. Clugston, A. Peel, J. McKirdy, and T.W.J. Moorhead White matter integrity in individuals at high genetic risk of bipolar disorder [published online ahead of print March 21] Biol Psychiatry 2011