Calmodulin and calcium differentially regulate the neuronal Nav1.1 voltage-dependent sodium channel

Biochemical and Biophysical Research Communications

Volumn 411, Issue 2, 2011, Pages 329-334

  Gaudioso, Christelle ^a,b   Carlier, Edmond ^a,b   Youssouf, Fahamoe ^a,b,d   Clare, Jeffrey J ^c   Debanne, Dominique ^a,b   Alcaraz, Gisèle ^a,b  

^a INSERM   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

^c Eaton Pharma Consulting   (United Kingdom)

^d CNRS   (France)

Author keywords

Calmodulin; SMEI; Voltage dependent sodium channel

Indexed keywords

CALCIUM; CALMODULIN; SODIUM CHANNEL NAV1.1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DEPOLARIZATION; FLUORESCENCE SPECTROSCOPY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYPERPOLARIZATION; KINETICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BRAIN; CALCIUM; CALMODULIN; HEK293 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEURONS; RATS; SODIUM CHANNELS; SPECTROMETRY, FLUORESCENCE; TWO-HYBRID SYSTEM TECHNIQUES;

RATTUS;

EID: 79960839492     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.06.142     Document Type: Article

References (29)

1. Dravet C. Les epilepsies graves de l'enfant. Vie Médicale 1978, 8:543-548.
2. Meisler M.H., Kearney J.A. Sodium channel mutations in epilepsy and other neurological disorders. J. Clin. Invest. 2005, 115:2010-2017.
3. Mulley J.C., Scheffer I.E., Petrou S., Dibbens L.M., Berkovic S.F., Harkin L.A. SCN1A mutations and epilepsy. Hum. Mutat. 2005, 25:535-542.
4. Ogiwara I., Miyamoto H., Morita N., Atapour N., Mazaki E., Inoue I., Takeuchi T., Itohara S., Yanagawa Y., Obata K., Furuichi T., Hensch T.K., Yamakawa K. Na(v)1. 1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation. J. Neurosci. 2007, 27:5903-5914.
5. Yu F.H., Mantegazza M., Westenbroek R.E., Robbins C.A., Kalume F., Burton K.A., Spain W.J., McKnight G.S., Scheuer T., Catterall W.A. Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy. Nat. Neurosci. 2006, 9:1142-1149.
6. Mantegazza M., Yu F.H., Catterall W.A., Scheuer T. Role of the C-terminal domain in inactivation of brain and cardiac sodium channels. Proc. Natl. Acad. Sci. USA 2001, 98:15348-15353.
7. Rhoads A.R., Friedberg F. Sequence motifs for calmodulin recognition. FASEB J. 1997, 11:331-340.
8. Choi J.S., Hudmon A., Waxman S.G., Dib-Hajj S.D. Calmodulin regulates current density frequency-dependent inhibition of sodium channel Nav1.8 in DRG neurons. J. Neurophysiol. 2006, 96:97-108.
9. Deschenes I., Neyroud N., DiSilvestre D., Marban E., Yue D.T., Tomaselli G.F. Isoform-specific modulation of voltage-gated Na(+) channels by calmodulin. Circ. Res. 2002, 90:E49-E57.
10. Herzog R.I., Liu C., Waxman S.G., Cummins T.R. Calmodulin binds to the C terminus of sodium channels Nav1. 4 Nav1.6 differentially modulates their functional properties. J. Neurosci. 2003, 23:8261-8270.
11. Kim J., Ghosh S., Liu H., Tateyama M., Kass R.S., Pitt G.S. Calmodulin mediates Ca2+ sensitivity of sodium channels. J. Biol. Chem. 2004, 279:45004-45012.
12. Lee-Kwon W., Goo J.H., Zhang Z., Silldorff E.P., Pallone T.L. Vasa recta voltage gated Na+ channel NaV1. 3 is regulated by calmodulin. Am. J. Physiol. Renal Physiol. 2006.
13. Mori M., Konno T., Morii T., Nagayama K., Imoto K. Regulatory interaction of sodium channel IQ-motif with calmodulin C-terminal lobe. Biochem. Biophys. Res. Commun. 2003, 307:290-296.
14. Tan H.L., Kupershmidt S., Zhang R., Stepanovic S., Roden D.M., Wilde A.A., Anderson M.E., Balser J.R. A calcium sensor in the sodium channel modulates cardiac excitability. Nature 2002, 415:442-447.
15. Young K.A., Caldwell J.H. Modulation of skeletal and cardiac voltage-gated sodium channels by calmodulin. J. Physiol. 2005, 565:349-370.
16. Wingo T.L., Shah V.N., Anderson M.E., Lybrand T.P., Chazin W.J., Balser J.R. An EF-hand in the sodium channel couples intracellular calcium to cardiac excitability. Nat. Struct. Mol. Biol. 2004, 11:219-225.
17. Chagot B., Potet F., Balser J.R., Chazin W.J. Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5. J. Biol. Chem. 2008.
18. Miloushev V.Z., Levine J.A., Arbing M.A., Hunt J.F., Pitt G.S., Palmer 3rd A.G. Solution structure of the NaV1. 2 C-terminal EF-hand domain. J. Biol. Chem. 2009.
19. Hartshorne R.P., Catterall W.A. The sodium channel from rat brain purification and subunit composition. J. Biol. Chem. 1984, 259:1667-1675.
20. Few A.P., Lautermilch N.J., Westenbroek R.E., Scheuer T., Catterall W.A. Differential regulation of CaV2. 1 channels by calcium-binding protein 1 visinin-like protein-2 requires N-terminal myristoylation. J. Neurosci. 2005, 25:7071-7080.
21. Rees S., Coote J., Stables J., Goodson S., Harris S., Lee M.G. Bicistronic vector for the creation of stable mammalian cell lines that predisposes all antibiotic-resistant cells to express recombinant protein. BioTechniques 1996, 20:102-104. 106, 108, 109, 110.
22. Fields S., Song O. A novel genetic system to detect protein-protein interactions. Nature 1989, 340:245-246.
23. Mori M., Konno T., Ozawa T., Murata M., Imoto K., Nagayama K. Novel interaction of the voltage-dependent sodium channel (VDSC) with calmodul does VDSC acquire calmodulin-mediated Ca2+ sensitivity?. Biochemistry 2000, 39:1316-1323.
24. Bahler M., Rhoads A. Calmodulin signaling via the IQ motif. FEBS Lett. 2002, 513:107-113.
25. Feldkamp M.D., Yu L., Shea M.A. Structural and Energetic Determinants of apo calmodulin binding to the IQ Motif of the Na(V)1.2 voltage-dependent sodium channel. Structure 2011, 19:733-747.
26. Shah V.N., Wingo T.L., Weiss K.L., Williams C.K., Balser J.R., Chazin W.J. Calcium-dependent regulation of the voltage-gated sodium channel hH1: intrinsic and extrinsic sensors use a common molecular switch. Proc. Natl. Acad. Sci. USA 2006, 103:3592-3597.
27. Rusconi R., Scalmani P., Cassulini R.R., Giunti G., Gambardella A., Franceschetti S., Annesi G., Wanke E., Mantegazza M. Modulatory proteins can rescue a trafficking defective epileptogenic Nav1. 1 Na+ channel mutant. J. Neurosci. 2007, 27:11037-11046.
28. Potet F., Chagot B., Anghelescu M., Viswanathan P.C., Stepanovic S.Z., Kupershmidt S., Chazin W.J., Balser J.R. Functional interactions between distinct sodium channel cytoplasmic domains through the action of calmodulin. J. Biol. Chem. 2009.
29. Motoike H.K., Liu H., Glaaser I.W., Yang A.S., Tateyama M., Kass R.S. The Na+ channel inactivation gate is a molecular complex: a novel role of the COOH-terminal domain. J. Gen. Physiol. 2004, 123:155-165.