Liver enzymes, Type 2 diabetes, and metabolic syndrome in middle-Aged, Urban Chinese men

Metabolic Syndrome and Related Disorders

Volumn 9, Issue 4, 2011, Pages 305-311

  Villegas, Raquel ^a   Xiang, Yong Bing ^b   Elasy, Tom ^c   Cai, Qiuyin ^c   Xu, Wanghong ^d   Li, Honglan ^b   Fazio, Sergio ^c   Linton, MacRae F ^c   Raiford, David ^c   Zheng, Wei ^c   Shu, Xiao Ou ^c  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b SHANGHAI CANCER INSTITUTE   (China)

^c VANDERBILT UNIVERSITY   (United States)

^d FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE;

ADULT; AGED; ARTICLE; CHINESE; COHORT ANALYSIS; HUMAN; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; POPULATION RESEARCH; PRIORITY JOURNAL; URBAN AREA;

ADULT; AGED; ALANINE TRANSAMINASE; ASIAN CONTINENTAL ANCESTRY GROUP; ASPARTATE AMINOTRANSFERASES; CHINA; COHORT STUDIES; DIABETES MELLITUS, TYPE 2; HUMANS; LIVER; MALE; METABOLIC SYNDROME X; MIDDLE AGED; MOTOR ACTIVITY; PREVALENCE; URBAN POPULATION;

EID: 79960827665     PISSN: 15404196     EISSN: 15578518     Source Type: Journal    
DOI: 10.1089/met.2011.0016     Document Type: Article

References (31)

1. Banfi G, Morelli P. Relation between body mass index and serum aminotransferases concentrations in professional athletes. J Sports Med Phys Fitness 2008;48:197-200.
2. Andre P, Balkau B, Born C, Royer B, Wilpart E, Charles MA, Eschwege E, and for the D.E.S.I.R. Study Group. Hepatic markers and development of type 2 diabetes in middle aged men and women: A three-year follow-up study. The D.E.S.I.R. Study (Data from an Epidemiological Study on the Insulin Resistance syndrome). Diabetes Metab 2005;31:542-550. (Pubitemid 43001171)
3. Adams LA, Waters OR, Knuiman MW, Elliott RR, Olynyk JK. NAFLD as a risk factor for the development of diabetes and the metabolic syndrome: An eleven-year follow-up study. Am J Gastroenterol 2009;104:861-867.
4. Jeong SK, Nam HS, Rhee JA, Shin JH, Kim JM, Cho KH.Metabolic syndrome and ALT: A community study in adult Koreans. Int J Obes Relat Metab Disord 2004;28:1033-1038.
5. Ioannou GN, Boyko EJ, Lee SP. The prevalence and predictors of elevated serum aminotransferase activity in the United States in 1999-2002. Am J Gastroenterol 2006;101:76-82. (Pubitemid 43381712)
6. Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002;346:1221-1231.
7. Song HR, Yun KE, Park HS. Relation between alanine aminotransferase concentrations and visceral fat accumulation among nondiabetic overweight Korean women. Am J Clin Nutr 2008;88:16-21. (Pubitemid 351988678)
8. Doi Y, Kubo M, Yonemoto K, Ninomiya T, Iwase M, Tanizaki Y, Shikata K, Iida M, Kiyohara Y. Liver enzymes as a predictor for incident diabetes in a Japanese population: The Hisayama study. Obesity (Silver Spring) 2007;15: 1841-1850. (Pubitemid 47264964)
9. Goessling W, Massaro JM, Vasan RS, D'Agostino RB, Sr., Ellison RC, Fox CS. Aminotransferase levels and 20-year risk of metabolic syndrome, diabetes, and cardiovascular disease. Gastroenterology 2008;135:1935-1944.
10. Hanley AJ, Williams K, Festa A, Wagenknecht LE, D'Agostino RB Jr, Kempf J, Zinman B, Haffner SM. Elevations in markers of liver injury and risk of type 2 diabetes: The insulin resistance atherosclerosis study. Diabetes 2004;53: 2623-2632. (Pubitemid 39299271)
11. Sattar N, Scherbakova O, Ford I, O'Reilly DS, Stanley A, Forrest E, MacFarlane PW, Packard CJ, Cobbe SM, Shepherd J. Elevated alanine aminotransferase predicts new-onset type 2 diabetes independently of classical risk factors, metabolic syndrome, and C-reactive protein in the west of Scotland coronary prevention study. Diabetes 2004;53:2855-2860. (Pubitemid 39425910)
12. Vozarova B, Stefan N, Lindsay RS, Saremi A, Pratley RE, Bogardus C, Tataranni PA. High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes. Diabetes 2002; 51:1889-1895. (Pubitemid 34564303)
13. Wannamethee SG, Shaper AG, Lennon L, Whincup PH. Hepatic enzymes, the metabolic syndrome, and the risk of type 2 diabetes in older men. Diabetes Care 2005;28:2913-2918. (Pubitemid 43942924)
14. Monami M, Bardini G, Lamanna C, Pala L, Cresci B, Francesconi P, Bulatti E, Rotella CM, Mannucci E. Liver enzymes and risk of diabetes and cardiovascular disease: Results of the Firenze Bagno a Ripoli (FIBAR) study. Metabolism 2008; 57:387-392. (Pubitemid 351178729)
15. Nannipieri M, Gonzales C, Baldi S, Posadas R, Williams K, Haffner SM, Stern MP, Ferrannini E. Liver enzymes, the metabolic syndrome, and incident diabetes: The Mexico City diabetes study. Diabetes Care 2005;28:1757-1762. (Pubitemid 40923089)
16. Loomba R, Bettencourt R, Barrett-Connor E. Synergistic association between alcohol intake and body mass index with serum alanine and aspartate aminotransferase levels in older adults: The Rancho Bernardo Study. Aliment Pharmacol Ther 2009;30:1137-1149.
17. Church TS, Kuk JL, Ross R, Priest EL, Biltoft E, Blair SN. Association of cardiorespiratory fitness, body mass index, and waist circumference to nonalcoholic fatty liver disease. Gastroenterology 2006;130:2023-2030. (Pubitemid 43816951)
18. Lawlor DA, Sattar N, Smith GD, Ebrahim S. The associations of physical activity and adiposity with alanine aminotransferase and gamma- glutamyltransferase. Am J Epidemiol 2005; 161:1081-1088. (Pubitemid 40734357)
19. Jurj AL, Wen W, Xiang YB, Matthews CE, Liu D, Zheng W, Shu X-O. Reproducibility and validity of the Shanghai Men's Health Study physical activity questionnaire. Am J Epidemiol 2007;165:1124-1133. (Pubitemid 47233711)
20. Ainsworth BE, Haskell WL, Whitt MC, Irwin ML, Swartz AM, Strath SJ, O'Brien WL, Bassett DR Jr, Schmitz KH, Emplaincourt PO, Jacobs DR Jr, Leon AS. Compendium of physical activities: An update of activity codes and MET intensities. Med Sci Sports Exerc 2000;32(9 Suppl):S498-S504.
21. Villegas R, Yang G, Liu D, Xiang YB, Cai H, Zheng W, Shu XO. Validity and reproducibility of the food-frequency questionnaire used in the Shanghai Men's Health Study. Br J Nutr 2007;97:993-1000. (Pubitemid 46554415)
22. Chinese Food Composition Tables. Beijing: Beijing University Medical Press; 2002.
23. Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC, Spertus JA, Costa F. Diagnosis and management of the metabolic syndrome. An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Executive summary. Cardiol Rev 2005;13:322-327. (Pubitemid 41579599)
24. Lee YS, Kek BL, Poh LK, Saw SM, Loke KY. Association of raised liver transaminases with physical inactivity, increased waist-hip ratio, and other metabolic morbidities in severely obese children. J Pediatr Gastroenterol Nutr 2008;47:172-178.
25. Perseghin G, Lattuada G, De CF, Ragogna F, Ntali G, Esposito A, Belloni E, Canu T, Terruzzi I, Scifo P, Del Maschio A, Luzi L. Habitual physical activity is associated with intrahepatic fat content in humans. Diabetes Care 2007; 30:683-688. (Pubitemid 46354353)
26. Spelberg A MJE. Towards prevention of non-insulin dependent diabetes mellitus. In: R.D.G. Leslie (ed.). Causes of Diabetes. Chichester: John Wiley & Sons; 1993; 319-345.
27. Park HS, Han JH, Choi KM, Kim SM. Relation between elevated serum alanine aminotransferase and metabolic syndrome in Korean adolescents. Am J Clin Nutr 2005;82: 1046-1051. (Pubitemid 43779763)
28. Saito T, Nishise Y, Makino N, Haga H, Ishii R, Okumoto K, Ito J-I, Watanabe H, Saito K, Takeda H, Togashi H, Kubota I, Daimon M, Kato T, Kawata S. Impact of metabolic syndrome on elevated serum alanine aminotransferase levels in the Japanese population. Metabolism 2009;58:1067-1075.
29. Forlani G, Di BP, Mannucci E, Capaldo B, Genovese S, Orrasch M, Scaldaferri L, Di Bartolo P, Melandri P, Dei Cas A, Zavaroni I, Marchesini G. Prevalence of elevated liver enzymes in Type 2 diabetes mellitus and its association with the metabolic syndrome. J Endocrinol Invest 2008;31: 146-52. (Pubitemid 351596975)
30. Daniel S, Ben-Menachem T, Vasudevan G, Ma CK, Blumenkehl M. Prospective evaluation of unexplained chronic liver transaminase abnormalities in asymptomatic and symptomatic patients. Am J Gastroenterol 1999;94:3010-3014. (Pubitemid 29482774)
31. Fan JG, Saibara T, Chitturi S, Kim BI, Sung JJ, Chutaputti A. What are the risk factors and settings for non-alcoholic fatty liver disease in Asia-Pacific? J Gastroenterol Hepatol 2007;22: 794-800. (Pubitemid 46911036)