Design, Implementation, Simulation, and Visualization of a Highly Efficient RIM Microfluidic Mixer for Rapid Freeze-Quench of Biological Samples

Applied Magnetic Resonance

Volumn 40, Issue 4, 2011, Pages 415-425

  Schmidt, Bryan ^a,c   Mahmud, Goher ^b   Soh, Siowling ^b   Kim, Sun Hee ^a,d   Page, Taylor ^a   O'Halloran, Thomas V ^a   Grzybowski, Bartosz A ^a,b   Hoffman, Brian M ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Northwestern University   (United States)

^c MINOT STATE UNIVERSITY   (United States)

^d Ewha Womans University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL REACTION; BIOLOGICAL SAMPLES; CHAOTIC FLOWS; HIGH VELOCITY; IMPINGING JET; MATHEMATICAL SIMULATIONS; MICROFLUIDIC MIXERS; MICROMIXERS; MICROSCOPIC VISUALIZATION; MIXING CHAMBER; MIXING METHOD; RELATIVELY LOW REYNOLDS NUMBERS; SPECTROSCOPIC STUDIES;

FLUIDIC DEVICES; MICROFLUIDICS; MIXERS (MACHINERY); MIXING; PLASTICS MOLDING; REACTION INTERMEDIATES; REYNOLDS NUMBER; SPECTROSCOPIC ANALYSIS; VISUALIZATION;

REACTION INJECTION MOLDING;

EID: 79960733720     PISSN: 09379347     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00723-011-0195-7     Document Type: Article

References (28)

1. C. Krebs, J. C. Price, J. Baldwin, L. Saleh, M. T. Green, J. M. Bollinger Jr., Inorg. Chem. 44, 742-757 (2005).
2. R. C. Bray, Biochem. J. 81, 189 (1961).
3. G. N. George, R. C. Bray, S. P. Cramer, Biochem. Soc. Trans. 14, 651 (1986).
4. D. Qiu, M. Kumar, S. W. Ragsdale, T. G. Spiro, J. Am. Chem. Soc. 117, 2653 (1995).
5. N. Mitic, L. Saleh, G. Schenk, J. M. Bollinger Jr., E. I. Solomon, J. Am. Chem. Soc. 125, 11200 (2003).
6. D. P. Ballou, G. Palmer, Anal. Chem. 46, 1248 (1974).
7. B. Schmidt, J. Mccracken, S. Ferguson-Miller, Proc. Natl. Acad. Sci. USA 100, 15539 (2003).
8. S. H. Kim, R. Perera, L. P. Hager, J. H. Dawson, B. M. Hoffman, J. Am. Chem. Soc. 128, 5598 (2006).
9. Y. Lin, G. J. Gerfen, D. L. Rousseau, S. R. Yeh, Anal. Chem. 75, 5381 (2003).
10. A. V. Cherepanov, S. De Vries, Biochim. Biophys. Acta Bioenerg. 1656, 1 (2004).
11. C. L. Tucker III, N. P. Suh, Polym. Eng. Sci. 20, 875 (1980).
12. L. J. Lee, J. M. Ottino, W. E. Ranz, C. W. Macosko, Polym. Eng. Sci. 20, 868 (1980).
13. A. J. Mahajan, D. J. Kirwan, AIChE J. 42, 1801 (1996).
14. A. M. Teixeira, R. J. Santos, M. R. P. F. N. Costa, J. C. B. Lopes, AIChE J. 51, 1608 (2005).
15. M. Tanaka, K. Matsuura, S. Yoshioka, S. Takahashi, K. Ishimori, H. Hori, I. Morishima, Biophys. J. 84, 1998 (2003).
16. W. K. Soh, B. C. Khoo, W. Y. D. Yuen, Exp. Fluids 39, 496 (2005).
17. W. B. Bald, J. Microsc. 140, 17 (1985).
18. A. A. S. Bhagat, E. T. K. Peterson, I. Papautsky, J. Micromech. Microeng. 17, 1017 (2007).
19. F. Schoenfeld, V. Hessel, C. Hofmann, Lab. Chip. 4, 65 (2004).
20. W. M. Deen, Analysis of Transport Phenomena (Oxford University Press, New York, 1998), pp. 191.
21. J. W. Shan, P. E. Dimotakis, J. Fluid. Mech. 566, 47 (2006).
22. J. Yao, Y. F. Yao, M. K. Patel, P. J. Mason, Eur. Phys. J. Appl. Phys. 37, 229 (2007).
23. H. Song, D. L. Chen, R. F. Ismagilov, Angew. Chem. Int. Ed. 45, 7336 (2006).
24. C. J. Campbell, B. A. Grzybowski, Philos. Trans. Ser. A Math. Phys. Eng. Sci. 362, 1069 (2004).
25. T. Egawa, J. L. Durand, E. Y. Hayden, D. L. Rousseau, S.-R. Yeh, Anal. Chem. 81, 1622 (2009).
26. P. Kolodziej, C. W. Macosko, W. E. Ranz, Polym. Eng. Sci. 22, 388 (1982).
27. B. K. Johnson, R. K. Prud'homme, AIChE J. 49, 2264 (2003).
28. A.-L. Tsai, V. Berka, R. J. Kulmacz, G. Wu, G. Palmer, Anal. Biochem. 264, 165 (1998).