Development of t(8;21) and RUNX1-RUNX1T1 in the Philadelphia-positive clone of a patient with chronic myelogenous leukemia: Additional evidence for multiple steps involved in disease progression

Cancer Genetics

Volumn 204, Issue 3, 2011, Pages 165-170

  Najfeld, Vesna ^a   Wisch, Nathaniel ^a   Mascarenhas, John ^a   Issa, Leonard ^a   Tripodi, Joseph ^a   Sidhu, Manpreet ^a   Hoffman, Ronald ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

AML; CML; Multistep pathogenesis; t(8; 21); T(9; 22)

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CD15 ANTIGEN; CD19 ANTIGEN; CD33 ANTIGEN; CD34 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; HLA DR ANTIGEN; IMATINIB; MICROSOMAL AMINOPEPTIDASE; NILOTINIB; STEM CELL FACTOR RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR RUNX1T1; UNCLASSIFIED DRUG; AML1 ETO FUSION PROTEIN, HUMAN; AML1-ETO FUSION PROTEIN, HUMAN; ONCOPROTEIN; RUNX1 PROTEIN, HUMAN; RUNX1T1 PROTEIN, HUMAN;

AGED; ALLOGENEIC STEM CELL TRANSPLANTATION; ARTICLE; BONE MARROW BIOPSY; CANCER CHEMOTHERAPY; CASE REPORT; CHRONIC MYELOID LEUKEMIA; DISEASE ASSOCIATION; DOSE RESPONSE; DRUG SAFETY; DRUG WITHDRAWAL; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DELETION; HUMAN; LEUKOPENIA; LOW DRUG DOSE; MALE; MALIGNANT TRANSFORMATION; PANCYTOPENIA; PHENOTYPE; PHILADELPHIA CHROMOSOME NEGATIVE CELL; PHLEBOTOMY; POLYCYTHEMIA; PRIORITY JOURNAL; THROMBOCYTE TRANSFUSION; THROMBOCYTOPENIA; TRISOMY 8; ADOLESCENT; ADULT; BLAST CELL CRISIS; CHROMOSOME 21; CHROMOSOME 8; DISEASE COURSE; FEMALE; GENE TRANSLOCATION; GENETICS; MIDDLE AGED; PATHOLOGY; PHILADELPHIA 1 CHROMOSOME; TRISOMY;

ADOLESCENT; ADULT; AGED; BLAST CRISIS; CHROMOSOMES, HUMAN, PAIR 21; CHROMOSOMES, HUMAN, PAIR 8; CORE BINDING FACTOR ALPHA 2 SUBUNIT; DISEASE PROGRESSION; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MALE; MIDDLE AGED; ONCOGENE PROTEINS, FUSION; PHILADELPHIA CHROMOSOME; PROTO-ONCOGENE PROTEINS; TRANSCRIPTION FACTORS; TRANSLOCATION, GENETIC; TRISOMY; YOUNG ADULT;

EID: 79960724606     PISSN: 22107762     EISSN: 22107770     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2010.09.001     Document Type: Article

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