Simultaneous occurrence of BCR/ABL1 and RUNX1/RUNX1T1 in a case of therapy-related acute myeloid leukemia

Cancer Genetics and Cytogenetics

Volumn 195, Issue 2, 2009, Pages 189-191

  Ammatuna, Emanuele ^a,b   Divona, Mariadomenica ^a,b   Curzi, Paola ^a,b   Panetta, Paola ^a,b   Zaza, Serena ^a,b   Postorino, Massimiliano ^a   Cantonetti, Maria ^a   Amadori, Sergio ^a   Lo Coco, Francesco ^a,b  

^a TOR VERGATA UNIVERSITY HOSPITAL   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; CD19 ANTIGEN; CD33 ANTIGEN; CD34 ANTIGEN; CISPLATIN; DACARBAZINE; DOXORUBICIN; ETOPOSIDE; HLA DR ANTIGEN; HYDROXYUREA; IFOSFAMIDE; IMATINIB; METHOTREXATE; MYELOPEROXIDASE; STEM CELL FACTOR RECEPTOR; TEMOZOLOMIDE; TRANSCRIPTION FACTOR RUNX1;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; ANEMIA; BONE MARROW EXAMINATION; CANCER RELAPSE; CASE REPORT; CONTROLLED STUDY; DRUG MEGADOSE; FEMALE; GENETIC ASSOCIATION; HUMAN; IMMUNOPHENOTYPING; LETTER; LEUKOCYTE COUNT; LUNG METASTASIS; MULTIPLE CYCLE TREATMENT; OSTEOSARCOMA; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THROMBOCYTOPENIA;

ADULT; ANTINEOPLASTIC AGENTS; CORE BINDING FACTOR ALPHA 2 SUBUNIT; ELECTROPHORESIS, AGAR GEL; FEMALE; GENES, ABL; HUMANS; KARYOTYPING; LEUKEMIA, MYELOID, ACUTE; PROTO-ONCOGENE PROTEINS; TRANSCRIPTION FACTORS;

EID: 70949091093     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2009.08.014     Document Type: Letter

References (12)

1. Paschka P. Core binding factor acute myeloid leukemia. Semin Oncol 35 (2008) 410-417
2. Xue Y.Q., Guo Y., Lu D.R., Gu J., Lu D.W., Gong J.X., Wang M.H., Zhu W.Y., and Lin B.J. A case of basophilic leukemia bearing simultaneous translocations t(8;21) and t(9;22). Cancer Genet Cytogenet 51 (1991) 215-221
3. Ferro M.T., Steegman J.L., Escribano L., Heiurichs B., Parada L., García-Sagredo J.M., Resino M., Cabello P., and San Román C. Ph-positive chronic myeloid leukemia with t(8;21)(q22;q22) in blastic crisis. Cancer Genet Cytogenet 58 (1992) 96-99
4. Kojima K., Yasukawa M., Ishimaru F., Dansako H., Matsuo Y., Kimura Y., Nawa Y., Hara M., and Harada M. Additional translocation (8;21)(q22;q22) in a patient with Philadelphia-positive chronic myelogenous leukaemia in the blastic phase. Br J Haematol 106 (1999) 720-722
5. Wu Y., Slovak M.L., Snyder D.S., and Arber D.A. Coexistence of inversion 16 and the Philadelphia chromosome in acute and chronic myeloid leukemias: report of six cases and review of literature. Am J Clin Pathol 125 (2006) 260-266
6. Preudhomme C., Lai J.L., Plantier I., Demory J.L., Zandecki M., and Fenaux P. Cytogenetic and molecular remission in a case of acute myeloid leukaemia (AML) with inversion of chromosome 16 (inv(16)) and Philadelphia chromosome (Ph). Br J Haematol 82 (1992) 623-626
7. Svaldi M., Lanthaler A., Venturi R., Coser P., and Mitterer M. Simultaneous occurrence of bcr-abl and inv 16 in a case of M1 acute myeloid leukemia. Leukemia 15 (2001) 695
8. Dallorso S., Sessarego M., Garrè M.L., Haupt R., Pasino M., and Sansone R. Secondary acute promyelocytic leukemia with t(8;21) and t(9;22) at onset and loss of the Philadelphia chromosome at relapse. Cancer Genet Cytogenet 47 (1990) 41-46
9. Najfeld V., Geller M., Troy K., and Scalise A. Acquisition of the Ph chromosome and BCR-ABL fusion product in AML-M2 and t(8;21) leukemia: cytogenetic and FISH evidence for a late event. Leukemia 12 (1998) 517-519
10. Pedersen-Bjergaard J., Andersen M.K., Andersen M.T., and Christiansen D.H. Genetics of therapy-related myelodysplasia and acute myeloid leukemia. Leukemia 22 (2008) 240-248
11. Deguchi K., and Gilliland D.G. Cooperativity between mutations in tyrosine kinases and in hematopoietic transcription factors in AML. Leukemia 16 (2002) 740-744
12. Kelly L.M., and Gilliland D.G. Genetics of myeloid leukemias. Annu Rev Genomics Hum Genet 3 (2002) 179-198