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Volumn 54, Issue 2, 2011, Pages 749-749

Silibinin mode(s) of action against hepatitis c virus: A controversy yet to be resolved

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; MERICITABINE; PEGINTERFERON ALPHA; PROTEINASE INHIBITOR; SILIBININ; SILYMARIN;

EID: 79960703901     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.24310     Document Type: Letter
Times cited : (9)

References (10)
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    • Differential in vitro effects of intravenous versus oral formulations of silibinin on the HCV life cycle and inflammation
    • Wagoner J, Morishima C, Graf TN, Oberlies NH, Teissier E, Pécheur EI, et al. Differential in vitro effects of intravenous versus oral formulations of silibinin on the HCV life cycle and inflammation. PLoS One 2011; 6: e16464.
    • (2011) PLoS One , vol.6
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  • 3
    • 77449092252 scopus 로고    scopus 로고
    • Silibinin and related compounds are direct inhibitors of hepatitis C virus RNA-dependent RNA polymerase
    • Ahmed-Belkacem A, Ahnou N, Barbotte L, Wychowski C, Pallier C, Brillet R, et al. Silibinin and related compounds are direct inhibitors of hepatitis C virus RNA-dependent RNA polymerase. Gastroenterology 2010; 138: 1112-1122.
    • (2010) Gastroenterology , vol.138 , pp. 1112-1122
    • Ahmed-Belkacem, A.1    Ahnou, N.2    Barbotte, L.3    Wychowski, C.4    Pallier, C.5    Brillet, R.6
  • 4
    • 55249084176 scopus 로고    scopus 로고
    • Silibinin is a potent antiviral agent in patients with chronic hepatitis C not responding to pegylated interferon/ribavirin therapy
    • Ferenci P, Scherzer TM, Kerschner H, Rutter K, Beinhardt S, Hofer H, et al. Silibinin is a potent antiviral agent in patients with chronic hepatitis C not responding to pegylated interferon/ribavirin therapy. Gastroenterology 2008; 135: 1561-1567.
    • (2008) Gastroenterology , vol.135 , pp. 1561-1567
    • Ferenci, P.1    Scherzer, T.M.2    Kerschner, H.3    Rutter, K.4    Beinhardt, S.5    Hofer, H.6
  • 5
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    • Rapid suppression of hepatitis C viremia induced by intravenous silibinin plus ribavirin
    • Biermer M, Berg T. Rapid suppression of hepatitis C viremia induced by intravenous silibinin plus ribavirin. Gastroenterology 2009; 137: 390-391.
    • (2009) Gastroenterology , vol.137 , pp. 390-391
    • Biermer, M.1    Berg, T.2
  • 6
    • 77956649719 scopus 로고    scopus 로고
    • Successful HCV eradication and inhibition of HIV replication by intravenous silibinin in an HIV-HCV coinfected patient
    • Payer BA, Reiberger T, Rutter K, Beinhardt S, Staettermayer AF, Peck-Radosavljevic M, et al. Successful HCV eradication and inhibition of HIV replication by intravenous silibinin in an HIV-HCV coinfected patient. J Clin Virol 2010; 49: 131-133.
    • (2010) J Clin Virol , vol.49 , pp. 131-133
    • Payer, B.A.1    Reiberger, T.2    Rutter, K.3    Beinhardt, S.4    Staettermayer, A.F.5    Peck-Radosavljevic, M.6
  • 7
    • 78349268362 scopus 로고    scopus 로고
    • RG7128 alone or in combination with pegylated interferon-α2a and ribavirin prevents hepatitis C virus (HCV) replication and selection of resistant variants in HCV-infected patients
    • Le Pogam S, Seshaadri A, Ewing A, Kang H, Kosaka A, Yan JM, et al. RG7128 alone or in combination with pegylated interferon-α2a and ribavirin prevents hepatitis C virus (HCV) replication and selection of resistant variants in HCV-infected patients. J Infect Dis 2010; 202: 1510-1519.
    • (2010) J Infect Dis , vol.202 , pp. 1510-1519
    • Le Pogam, S.1    Seshaadri, A.2    Ewing, A.3    Kang, H.4    Kosaka, A.5    Yan, J.M.6
  • 8
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    • A perspective on modelling hepatitis C virus infection
    • Guedj J, Rong L, Dahari H, Perelson AS. A perspective on modelling hepatitis C virus infection. J Viral Hepat 2010; 17: 825-833.
    • (2010) J Viral Hepat , vol.17 , pp. 825-833
    • Guedj, J.1    Rong, L.2    Dahari, H.3    Perelson, A.S.4
  • 9
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  • 10
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    • Modeling interferon-alpha mediated inhibition kinetics of intracellular and extracellular HCV RNA during HCV infection in vitro
    • Dahari H, Barretto N, Sainz B Jr, Guedj J, Perelson AS, Uprichard SL. Modeling interferon-alpha mediated inhibition kinetics of intracellular and extracellular HCV RNA during HCV infection in vitro. J Hepatol 2011; 54( Suppl 1): S312.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.