Intensity-modulated radiation therapy versus conventional radiation therapy for squamous cell carcinoma of the anal canal

Cancer

Volumn 117, Issue 15, 2011, Pages 3342-3351

  Bazan, Jose G ^a   Hara, Wendy ^a   Hsu, Annie ^a   Kunz, Pamela A ^b   Ford, James ^b   Fisher, George A ^b   Welton, Mark L ^b   Shelton, Andrew ^b   Kapp, Daniel S ^a   Koong, Albert C ^a   Goodman, Karyn A ^c   Chang, Daniel T ^a  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^b STANFORD UNIVERSITY   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

anal canal; conventional radiation; IMRT; outcomes; squamous cell carcinoma; toxicity

Indexed keywords

CAPECITABINE; CISPLATIN; FLUOROURACIL; MITOMYCIN C;

ADULT; ANGINA PECTORIS; ANUS CARCINOMA; ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER STAGING; CLINICAL ARTICLE; COLITIS; CONTINUOUS INFUSION; CONTROLLED STUDY; CONVENTIONAL RADIATION THERAPY; CORONARY ARTERY DISEASE; DESQUAMATION; FEMALE; FOLLOW UP; GASTROINTESTINAL TOXICITY; HUMAN; INTENSITY MODULATED RADIATION THERAPY; LYMPH NODE METASTASIS; MALE; OVERALL SURVIVAL; PNEUMONIA; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RADIATION DOSE; RETROSPECTIVE STUDY; SEPTIC SHOCK; SKIN TOXICITY; SQUAMOUS CELL CARCINOMA; STROKE; TREATMENT DURATION; TREATMENT RESPONSE;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; ANUS NEOPLASMS; CARCINOMA, SQUAMOUS CELL; CISPLATIN; COMBINED MODALITY THERAPY; FEMALE; FLUOROURACIL; HUMANS; MALE; MIDDLE AGED; MITOMYCIN; RADIOTHERAPY; RADIOTHERAPY DOSAGE; SURVIVAL ANALYSIS;

EID: 79960700562     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.25901     Document Type: Article

References (29)

1. Nigro ND, Vaitkevicius VK, Considine B Jr. , Combined therapy for cancer of the anal canal: a preliminary report. 1974. Dis Colon Rectum. 1993; 36: 709-711.
2. Poggi MM, Suh WW, Saltz L, et al. ACR Appropriateness Criteria on treatment of anal cancer. J Am Coll Radiol. 2007; 4: 448-456. (Pubitemid 46970907)
3. Minsky BD., Anal cancer. In:, Leibel SA, Phillips TL, eds. Textbook of Radiation Oncology. Philadelphia: WB Saunders; 2004: 913-921.
4. Chen YJ, Liu A, Tsai PT, et al. Organ sparing by conformal avoidance intensity-modulated radiation therapy for anal cancer: dosimetric evaluation of coverage of pelvis and inguinal/femoral nodes. Int J Radiat Oncol Biol Phys. 2005; 63: 274-281. (Pubitemid 41583568)
5. Milano MT, Jani AB, Farrey KJ, et al. Intensity-modulated radiation therapy (IMRT) in the treatment of anal cancer: toxicity and clinical outcome. Int J Radiat Oncol Biol Phys. 2005; 63: 354-361. (Pubitemid 41317151)
6. Pepek JM, Willett CG, Wu QJ, Yoo S, Clough RW, Czito BG., Intensity-modulated radiation therapy for anal malignancies: a preliminary toxicity and disease outcomes analysis. Int J Radiat Oncol Biol Phys. 2010; 78: 1413-1419.
7. Salama JK, Mell LK, Schomas DA, et al. Concurrent chemotherapy and intensity-modulated radiation therapy for anal canal cancer patients: a multicenter experience. J Clin Oncol. 2007; 25: 4581-4586. (Pubitemid 350035316)
8. Trotti A, Colevas AD, Setser A, et al. CTCAE v3.0: development of a comprehensive grading system for the adverse effects of cancer treatment. Semin Radiat Oncol. 2003; 13: 176-181. (Pubitemid 36962641)
9. Epidermoid anal cancer: results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin. UKCCCR Anal Cancer Trial Working Party. UK Co-ordinating Committee on Cancer Res. Lancet. 1996; 348: 1049-1054.
10. Bartelink H, Roelofsen F, Eschwege F, et al. Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups. J Clin Oncol. 1997; 15: 2040-2049. (Pubitemid 27209535)
11. Flam M, John M, Pajak TF, et al. Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study. J Clin Oncol. 1996; 14: 2527-2539. (Pubitemid 26300120)
12. Allal AS, Sprangers MA, Laurencet F, et al. Assessment of long-term quality of life in patients with anal carcinomas treated by radiotherapy with or without chemotherapy. Br J Cancer. 1999; 80: 1588-1594. (Pubitemid 29308641)
13. Ajani JA, Winter KA, Gunderson LL, et al. Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial. JAMA. 2008; 299: 1914-1921. (Pubitemid 351574921)
14. Bourhis J, Overgaard J, Audry H, et al. Hyperfractionated or accelerated radiotherapy in head and neck cancer: a meta-analysis. Lancet. 2006; 368: 843-854. (Pubitemid 44292807)
15. Chen SW, Liang JA, Yang SN, et al. The adverse effect of treatment prolongation in cervical cancer by high-dose-rate intracavitary brachytherapy. Radiother Oncol. 2003; 67: 69-76.
16. Girinsky T, Rey A, Roche B, et al. Overall treatment time in advanced cervical carcinomas: a critical parameter in treatment outcome. Int J Radiat Oncol Biol Phys. 1993; 27: 1051-1056.
17. Nguyen LN, Ang KK., Radiotherapy for cancer of the head and neck: altered fractionation regimens. Lancet Oncol. 2002; 3: 693-701. (Pubitemid 35314913)
18. Lanciano RM, Pajak TF, Martz K, et al. The influence of treatment time on outcome for squamous cell cancer of the uterine cervix treated with radiation: a patterns-of-care study. Int J Radiat Oncol Biol Phys. 1993; 25: 391-397. (Pubitemid 23068703)
19. Guerrero Urbano MT, Henrys AJ, Adams EJ, et al. Intensity-modulated radiotherapy in patients with locally advanced rectal cancer reduces volume of bowel treated to high dose levels. Int J Radiat Oncol Biol Phys. 2006; 65: 907-916. (Pubitemid 43795830)
20. Mundt AJ, Mell LK, Roeske JC., Preliminary analysis of chronic gastrointestinal toxicity in gynecology patients treated with intensity-modulated whole pelvic radiation therapy. Int J Radiat Oncol Biol Phys. 2003; 56: 1354-1360. (Pubitemid 36842887)
21. Cummings BJ, Keane TJ, O'Sullivan B, et al. Epidermoid anal cancer: treatment by radiation alone or by radiation and 5-fluorouracil with and without mitomycin C. Int J Radiat Oncol Biol Phys. 1991; 21: 1115-1125.
22. Schlienger M, Krzisch C, Pene F, et al. Epidermoid carcinoma of the anal canal treatment results and prognostic variables in a series of 242 cases. Int J Radiat Oncol Biol Phys. 1989; 17: 1141-1151. (Pubitemid 20028629)
23. Hong JJ, Park W, Ehrenpreis ED., Review article: current therapeutic options for radiation proctopathy. Aliment Pharmacol Ther. 2001; 15: 1253-1262. (Pubitemid 32835531)
24. Huang K, Haas-Kogan D, Weinberg V, et al. Higher radiation dose with a shorter treatment duration improves outcome for locally advanced carcinoma of anal canal. World J Gastroenterol. 2007; 13: 895-900. (Pubitemid 46470300)
25. Peiffert D, Seitz JF, Rougier P, et al. Preliminary results of a phase II study of high-dose radiation therapy and neoadjuvant plus concomitant 5-fluorouracil with CDDP chemotherapy for patients with anal canal cancer: a French cooperative study. Ann Oncol. 1997; 8: 575-581. (Pubitemid 127746490)
26. Roohipour R, Patil S, Goodman KA, et al. Squamous-cell carcinoma of the anal canal: predictors of treatment outcome. Dis Colon Rectum. 2008; 51: 147-153.
27. Konski A, Garcia, M Jr, John M, et al. Evaluation of planned treatment breaks during radiation therapy for anal cancer: update of RTOG 92-08. Int J Radiat Oncol Biol Phys. 2008; 72: 114-118.
28. Meyer A, Meier Zu Eissen J, Karstens JH, et al. Chemoradiotherapy in patients with anal cancer: impact of length of unplanned treatment interruption on outcome. Acta Oncol. 2006; 45: 728-735.
29. Ben-Josef E, Moughan J, Ajani JA, et al. Impact of overall treatment time on survival and local control in patients with anal cancer: a pooled data analysis of Radiation Therapy Oncology Group Trials 87-04 and 98-11. J Clin Oncol. 2010; 28: 5061-5066.