Influence of SCARB1 polymorphisms on serum lipids of hypercholesterolemic individuals treated with atorvastatin

Clinica Chimica Acta

Volumn 411, Issue 9-10, 2010, Pages 631-637

  Cerda, Álvaro ^a   Genvigir, Fabiana D V ^a   Arazi, Simone S ^a   Hirata, Mario H ^a   Dorea, Egidio L ^a   Bernik, Marcia M S ^a   Bertolami, Marcelo C ^b   Faludi, Andre A ^b   Hirata, Rosario D C ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO DANTE PAZZANESE DE CARDIOLOGIA   (Brazil)

Author keywords

Atorvastatin; Cholesterol; Pharmacogenenomics; Polymorphisms; SCARB1; Scavenger receptor BI

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN B; ATORVASTATIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SCAVENGER RECEPTOR BI;

ADULT; ALLELE; ARTICLE; BRAZIL; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG RESPONSE; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOSITY; HUMAN; HYPERCHOLESTEROLEMIA; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PHARMACOGENETICS; PREDICTION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; AGED, 80 AND OVER; ANTICHOLESTEREMIC AGENTS; APOLIPOPROTEIN A-I; APOLIPOPROTEINS B; BLOOD; BRAZIL; CHOLESTEROL; CHOLESTEROL, HDL; CHOLESTEROL, LDL; FEMALE; GENE FREQUENCY; GENOTYPE; HAPLOTYPES; HEPTANOIC ACIDS; HUMANS; HYPERCHOLESTEROLEMIA; LINKAGE DISEQUILIBRIUM; LIPID METABOLISM; LIPIDS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PYRROLES; SCAVENGER RECEPTORS, CLASS B; TRIGLYCERIDES;

EID: 77950458892     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2010.01.002     Document Type: Article

References (41)

1. Trigatti B., Krieger M., Rigotti A. Influence of the HDL receptor SR-BI on lipoprotein metabolism and atherosclerosis. Arterioscler Thromb Vasc Biol 2003, 23:1732-1738.
2. Acton S., Rigotti A., Landschulz K.T., Xu S., Hobbs H.H., Krieger M. Identification of scavenger receptor SR-BI as a high density lipoprotein receptor. Science 1996, 271:518-520.
3. Pagler T.A., Rhode S., Neuhofer A., et al. SR-BI-mediated high density lipoprotein (HDL) endocytosis leads to HDL resecretion facilitating cholesterol efflux. J Biol Chem 2006, 281:1193-1204.
4. Calvo D., Gomez-Coronado D., Lasuncion M.A., Vega M.A. CLA-1 is an 85-kD plasma membrane glycoprotein that acts as a high-affinity receptor for both native (HDL, LDL, and VLDL) and modified (OxLDL and AcLDL) lipoproteins. Arterioscler Thromb Vasc Biol 1997, 17:2341-2349.
5. Acton S.L., Scherer P.E., Lodish H.F., Krieger M. Expression cloning of SR-BI, a CD36-related class B scavenger receptor. J Biol Chem 1994, 269:21003-21009.
6. Wang N., Arai T., Ji Y., Rinninger F., Tall A.R. Liver-specific overexpression of scavenger receptor BI decreases concentrations of very low density lipoprotein ApoB, low density lipoprotein ApoB, and high density lipoprotein in transgenic mice. J Biol Chem 1998, 273:32920-32926.
7. Van Eck M., Hoekstra M., Out R., et al. Scavenger receptor BI facilitates the metabolism of VLDL lipoproteins in vivo. J Lipid Res 2008, 49:136-146.
8. Rhainds D., Brodeur M., Lapointe J., Charpentier D., Falstrault L., Brissette L. The role of human and mouse hepatic scavenger receptor class B type I (SR-BI) in the selective uptake of low-density lipoprotein-cholesteryl esters. Biochemistry 2003, 42:7527-7538.
9. Acton S., Osgood D., Donoghue M., et al. Association of polymorphisms at the SR-BI gene locus with plasma lipid concentrations and body mass index in a white population. Arterioscler Thromb Vasc Biol 1999, 19:1734-1743.
10. Osgood D., Corella D., Demissie S., et al. Genetic variation at the scavenger receptor class b type I gene locus determines plasma lipoprotein concentrations and particle size and interacts with type 2 diabetes: the Framingham study. J Clin Endocrinol Metab 2003, 88:2869-2879.
11. Pérez-Martínez P., Ordovás J.M., López-Miranda J., et al. Polymorphism exon 1 variant at the locus of the scavenger receptor class B type I gene: influence on plasma LDL cholesterol in healthy subjects during the consumption of diets with different fat contents. Am J Clin Nutr 2003, 77:809-813.
12. Rodríguez-Esparragón F., Rodríguez-Pérez J.C., Hernández-Trujillo Y., et al. Allelic variants of the human scavenger receptor class B type 1 and paraoxonase 1 on coronary heart disease: genotype-phenotype correlations. Arterioscler Thromb Vasc Biol 2005, 25:854-860.
13. Roberts C.G., Shen H., Mitchell B.D., Damcott C.M., Shuldiner A.R., Rodriguez A. Variants in scavenger receptor class B type I gene are associated with HDL cholesterol concentrations in younger women. Hum Hered 2007, 64:107-113.
14. Tanaka T., Delgado-Lista J., Lopez-Miranda J., et al. Scavenger receptor class B type I (SCARB1) c.1119C>T polymorphism affects postprandial triglyceride metabolism in men. J Nutr 2007, 137:578-582.
15. Liu Y., Ordovas J.M., Gao G., et al. The SCARB1 gene is associated with lipid response to dietary and pharmacological interventions. J Hum Genet 2008, 53:709-717.
16. Vaughan C.J., Gotto A.M. Update on statins: 2003. Circulation 2004, 110:886-892.
17. Baigent C., Keech A., Kearney P.M., et al. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet 2005, 366:1267-1278.
18. Brown M.S., Goldstein J.L. Lowering plasma cholesterol by raising LDL receptors. 1981. Atheroscler Suppl 2004, 5:57-59.
19. Wang C.Y., Liu P.Y., Liao J.K. Pleiotropic effects of statin therapy: molecular mechanisms and clinical results. Trends Mol Med 2008, 14:37-44.
20. Hou R., Goldberg A.C. Lowering low-density lipoprotein cholesterol: statins, ezetimibe, bile acid sequestrants, and combinations: comparative efficacy and safety. Endocrinol Metab Clin North Am 2009, 38:79-97.
21. Rodrigues A.C., Hirata M.H., Hirata R.D. The genetic determinants of atorvastatin response. Curr Opin Mol Ther 2007, 9:545-553.
22. Mangravite L.M., Wilke R.A., Zhang J., Krauss R.M. Pharmacogenomics of statin response. Curr Opin Mol Ther 2008, 10:555-561.
23. Genvigir F.D., Soares S.A., Hirata M.H., et al. Effects of ABCA1 SNPs, including the C-105T novel variant, on serum lipids of Brazilian individuals. Clin Chim Acta 2008, 389:79-86.
24. Chahoud G., Aude Y.W., Mehta J.L. Dietary recommendations in the prevention and treatment of coronary heart disease: do we have the ideal diet yet?. Am J Cardiol 2004, 94:1260-1267.
25. Friedewald W.T., Levy R.I., Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972, 18:499-502.
26. Thompson A., Danesh J. Associations between apolipoprotein B, apolipoprotein AI, the apolipoprotein B/AI ratio and coronary heart disease: a literature-based meta-analysis of prospective studies. J Intern Med 2006, 259:481-492.
27. Salazar L.A., Hirata M.H., Cavalli S.A., Machado M.O., Hirata R.D.C. Optimized procedure for DNA isolation from fresh and cryopreserved clotted human blood useful in clinical molecular testing. Clin Chem 1998, 44:1748-1750.
28. Excoffier L., Laval G., Schneider S. Arlequin ver. 3.0: an integrated software package for population genetics data analysis. Evol Bioinform Online 2005, 1:47-50.
29. Yoo J., Seo B., Kim Y. SNPAnalyzer: a web-based integrated workbench for single-nucleotide polymorphism analysis. Nucleic Acids Res 2005, 33:W483-438.
30. Le Jossec M., Wambach T., Labuda D., Sinnett D., Levy E. Genetic diversity patterns in the SR-BI/II locus can be explained by a recent selective sweep. Mol Biol Evol 2004, 21:760-769.
31. Ritsch A., Sonderegger G., Sandhofer A., et al. Scavenger receptor class B type I polymorphisms and peripheral arterial disease. Metabolism 2007, 56:1135-1141.
32. McCarthy J.J., Lehner T., Reeves C., et al. Association of genetic variants in the HDL receptor, SR-B1, with abnormal lipids in women with coronary artery disease. J Med Genet 2003, 40:453-458.
33. Suarez-Kurtz G., Perini J.A., Bastos-Rodrigues L., Pena S.D., Struchiner C. Impact of population admixture on the distribution of the CYP3A5*3 polymorphism. Pharmacogenomics 2007, 8:1299-1306.
34. McCarthy J.J., Somji A., Weiss L.A., et al. Polymorphisms of the scavenger receptor class B member 1 are associated with insulin resistance with evidence of gene by sex interaction. J Clin Endocrinol Metab 2009, 94:1789-1796.
35. Kozarsky K.F., Donahee M.H., Rigotti A., Iqbal S.N., Edelman E.R., Krieger M. Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol concentrations. Nature 1997, 387:414-417.
36. Ueda Y., Royer L., Gong E., et al. Lower plasma concentrations and accelerated clearance of high density lipoprotein (HDL) and non-HDL cholesterol in scavenger receptor class B type I transgenic mice. J Biol Chem 1999, 274:7165-7171.
37. Huszar D., Varban M.L., Rinninger F., et al. Increased LDL cholesterol and atherosclerosis in LDL receptor-deficient mice with attenuated expression of scavenger receptor B1. Arterioscler Thromb Vasc Biol 2000, 20:1068-1073.
38. Tai E.S., Adiconis X., Ordovas J.M., et al. Polymorphisms at the SRBI locus are associated with lipoprotein concentrations in subjects with heterozygous familial hypercholesterolemia. Clin Genet 2003, 63:53-58.
39. West M., Greason E., Kolmakova A., et al. Scavenger receptor class B type I protein as an independent predictor of high-density lipoprotein cholesterol concentrations in subjects with hyperalphalipoproteinemia. J Clin Endocrinol Metab 2009, 94:1451-1457.
40. Pérez-Martínez P., Pérez-Jiménez F., Bellido C., et al. A polymorphism exon 1 variant at the locus of the scavenger receptor class B type I (SCARB1) gene is associated with differences in insulin sensitivity in healthy people during the consumption of an olive oil-rich diet. J Clin Endocrinol Metab 2005, 90:2297-2300.
41. Connelly M.A., De La Llera-Moya M., Monzo P., et al. Analysis of chimeric receptors shows that multiple distinct functional activities of scavenger receptor, class B, type I (SR-BI), are localized to the extracellular receptor domain. Biochemistry 2001, 40:5249-5259.