What real influence does the proto-oncogene c-myc have in OSCC behavior?

Oral Oncology

Volumn 47, Issue 8, 2011, Pages 688-692

  Pérez Sayáns, Mario ^a   Suárez Peñaranda, José Manuel ^b   Pilar, Gayoso Diz ^a,b   Barros Angueira, Francisco ^b   Gándara Rey, José Manuel ^c   García García, Abel ^a  

^a Santiago University Clinical Hospital   (Spain)

^b Instituto de Salud Carlos III   (Spain)

^c Hospital Clínico Universitario de Santiago de Compostela ^*  (Spain)

Author keywords

C myc; Genetic amplification; Oncogene; Oral squamous cell carcinoma (OSCC)

Indexed keywords

MYC PROTEIN;

APOPTOSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; GENE AMPLIFICATION; GENE EXPRESSION; GENE FUNCTION; HUMAN; IMMUNOHISTOCHEMISTRY; MOUTH CARCINOMA; ONCOGENE C MYC; PRIORITY JOURNAL; PROTO ONCOGENE; REVIEW; SQUAMOUS CELL CARCINOMA;

CARCINOMA, SQUAMOUS CELL; GENE AMPLIFICATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MOUTH NEOPLASMS; ONCOGENES; PROTO-ONCOGENE PROTEINS C-MYC;

EID: 79960697169     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2011.05.016     Document Type: Review

References (56)

1. M. Perez-Sayans, J.M. Somoza-Martin, F. Barros-Angueira, M.D. Reboiras-Lopez, J.M. Gandara Rey, and A. Garcia-Garcia Genetic and molecular alterations associated with oral squamous cell cancer (review) Oncol Rep 22 2009 1277 1282
2. S. Choi, and J.N. Myers Molecular pathogenesis of oral squamous cell carcinoma: implications for therapy J Dent Res 87 2008 14 32
3. E. Vairaktaris, S. Spyridonidou, V. Papakosta, A. Vylliotis, A. Lazaris, and D. Perrea The hamster model of sequential oral oncogenesis Oral Oncol 44 2008 315 324 (Pubitemid 351380986)
4. M.A. Ginos, G.P. Page, B.S. Michalowicz, K.J. Patel, S.E. Volker, and S.E. Pambuccian Identification of a gene expression signature associated with recurrent disease in squamous cell carcinoma of the head and neck Cancer Res 64 2004 55 63 (Pubitemid 38114082)
5. N.G. Shah, T.I. Trivedi, R.A. Tankshali, J.V. Goswami, D.H. Jetly, and S.N. Shukla Prognostic significance of molecular markers in oral squamous cell carcinoma: A multivariate analysis Head Neck 31 2009 1544 1556
6. J. Koehn, K. Krapfenbauer, S. Huber, E. Stein, W. Sutter, and F. Watzinger Potential involvement of MYC- and p53-related pathways in tumorigenesis in human oral squamous cell carcinoma revealed by proteomic analysis J Proteome Res 7 2008 3818 3829
7. D.A. Spandidos, A. Lamothe, and J.K. Field Multiple transcriptional activation of cellular oncogenes in human head and neck solid tumours Anticancer Res 5 1985 221 224
8. P. Gallant, and D. Steiger Myc's secret life without max Cell Cycle 8 2009 3848 3853
9. S. Pelengaris, M. Khan, and G. Evan C-MYC: more than just a matter of life and death Nat Rev Cancer 2 2002 764 776 (Pubitemid 37328911)
10. D.A. Whyte, C.E. Broton, and E.J. Shillitoe The unexplained survival of cells in oral cancer: What is the role of p53? J Oral Pathol Med 31 2002 125 133 (Pubitemid 34432217)
11. R. Lebofsky, and J.C. Walter New myc-anisms for DNA replication and tumorigenesis? Cancer Cell 12 2007 102 103 (Pubitemid 47199128)
12. D.A. Spandidos, M. Yiagnisis, K. Papadimitriou, and J.K. Field Ras, c-myc and c-erbB-2 oncoproteins in human breast cancer Anticancer Res 9 1989 1385 1393
13. J.M. Varley, J.E. Swallow, W.J. Brammar, J.L. Whittaker, and R.A. Walker Alterations to either c-erbB-2(neu) or c-myc proto-oncogenes in breast carcinomas correlate with poor short-term prognosis Oncogene 1 1987 423 430 (Pubitemid 17159256)
14. G.F. Riou Proto-oncogenes and prognosis in early carcinoma of the uterine cervix Cancer Surv 7 1988 441 456
15. J.K. Field, D.A. Spandidos, P.M. Stell, E.D. Vaughan, G.I. Evan, and J.P. Moore Elevated expression of the c-myc oncoprotein correlates with poor prognosis in head and neck squamous cell carcinoma Oncogene 4 1989 1463 1468 (Pubitemid 20008925)
16. M. Nakagawa, N. Takizawa, M. Narita, T. Ichisaka, and S. Yamanaka Promotion of direct reprogramming by transformation-deficient myc Proc Natl Acad Sci USA 107 2010 14152 14157
17. J.M. Adams, P.N. Kelly, A. Dakic, S. Carotta, S.L. Nutt, and A. Strasser Role of "cancer stem cells" and cell survival in tumor development and maintenance Cold Spring Harb Symp Quant Biol 73 2008 451 459
18. M. Eilers, and R.N. Eisenman Myc's broad reach Genes Dev 22 2008 2755 2766
19. S.K. Nair, and S.K. Burley Structural aspects of interactions within the Myc/Max/Mad network Curr Top Microbiol Immunol 302 2006 123 143 (Pubitemid 43268505)
20. C.S. Teng Protooncogenes as mediators of apoptosis Int Rev Cytol 197 2000 137 202
21. G. Martin-Ezquerra, R. Salgado, A. Toll, M. Gilaberte, T. Baro, and F. Alameda Quitllet Multiple genetic copy number alterations in oral squamous cell carcinoma: study of MYC, TP53, CCDN1, EGFR and ERBB2 status in primary and metastatic tumours Br J Dermatol 163 2010 1028 1035
22. L. Soucek, J. Whitfield, C.P. Martins, A.J. Finch, D.J. Murphy, and N.M. Sodir Modelling myc inhibition as a cancer therapy Nature 455 7213 2008 679 683
23. D. Dominguez-Sola, C.Y. Ying, C. Grandori, L. Ruggiero, B. Chen, and M. Li Non-transcriptional control of DNA replication by c-myc Nature 448 2007 445 451 (Pubitemid 47123512)
24. G. Goessel, M. Quante, W.C. Hahn, H. Harada, S. Heeg, and Y. Suliman Creating oral squamous cancer cells: a cellular model of oral-esophageal carcinogenesis Proc Natl Acad Sci USA 102 2005 15599 15604 (Pubitemid 41528102)
25. K.W. Foster, S. Ren, I.D. Louro, S.M. Lobo-Ruppert, P. McKie-Bell, and W. Grizzle Oncogene expression cloning by retroviral transduction of adenovirus E1A-immortalized rat kidney RK3E cells: Transformation of a host with epithelial features by c-MYC and the zinc finger protein GKLF Cell Growth Differ 10 1999 423 434 (Pubitemid 29284184)
26. H. Sakai, K. Kawano, K. Okamura, and N. Hashimoto Immunohistochemical localization of c-myc oncogene product and EGF receptor in oral squamous cell carcinoma J Oral Pathol Med 19 1990 1 4 (Pubitemid 20128758)
27. L.R. Eversole, and J.P. Sapp C-myc oncoprotein expression in oral precancerous and early cancerous lesions Eur J Cancer B Oral Oncol 29B 1993 131 135 (Pubitemid 23156618)
28. R. Baral, S. Patnaik, and B.R. Das Co-overexpression of p53 and c-myc proteins linked with advanced stages of betel- and tobacco-related oral squamous cell carcinomas from eastern india Eur J Oral Sci 106 1998 907 913 (Pubitemid 128737081)
29. K. Freier, F.X. Bosch, C. Flechtenmacher, F. Devens, A. Benner, and P. Lichter Distinct site-specific oncoprotein overexpression in head and neck squamous cell carcinoma: a tissue microarray analysis Anticancer Res 23 2003 3971 3977 (Pubitemid 37474351)
30. H.H. Vora, N.G. Shah, D.D. Patel, T.I. Trivedi, and P.R. Chikhlikar Prognostic significance of biomarkers in squamous cell carcinoma of the tongue: Multivariate analysis J Surg Oncol 82 2003 34 50 (Pubitemid 36055489)
31. R.P. Takes, R.J. Baatenburg de Jong, E. Schuuring, S.V. Litvinov, J. Hermans, and J.H. Van Krieken Differences in expression of oncogenes and tumor suppressor genes in different sites of head and neck squamous cell Anticancer Res 18 1998 4793 4800 (Pubitemid 29042062)
32. N.G. Shah, T.I. Trivedi, R.A. Tankshali, J.A. Goswami, J.S. Shah, and D.H. Jetly Molecular alterations in oral carcinogenesis: significant risk predictors in malignant transformation and tumor progression Int J Biol Markers 22 2007 132 143 (Pubitemid 47062218)
33. S. Fujieda, M. Inuzuka, N. Tanaka, H. Sunaga, G.K. Fan, and T. Ito Expression of p27 is associated with bax expression and spontaneous apoptosis in oral and oropharyngeal carcinoma Int J Cancer 84 1999 315 320 (Pubitemid 29256761)
34. V. Hayry, L.K. Makinen, T. Atula, H. Sariola, A. Makitie, and I. Leivo Bmi-1 expression predicts prognosis in squamous cell carcinoma of the tongue Br J Cancer 102 2010 892 897
35. R.P. Takes, R.J. Baatenburg de Jong, K. Wijffels, E. Schuuring, S.V. Litvinov, and J. Hermans Expression of genetic markers in lymph node metastases compared with their primary tumours in head and neck cancer J Pathol 194 2001 298 302 (Pubitemid 32624555)
36. J.P. Rodrigo, P.S. Lazo, S. Ramos, I. Alvarez, and C. Suarez MYC amplification in squamous cell carcinomas of the head and neck Arch Otolaryngol Head Neck Surg 122 1996 504 507 (Pubitemid 26153860)
37. H. Tsuzuki, H. Sunaga, T. Ito, N. Narita, C. Sugimoto, and S. Fujieda Reliability of platelet-derived endothelial cell growth factor as a prognostic factor for oral and oropharyngeal carcinomas Arch Otolaryngol Head Neck Surg 131 2005 1071 1078 (Pubitemid 41815881)
38. M.K. Kang, R.H. Kim, S.J. Kim, F.K. Yip, K.H. Shin, and G.P. Dimri Elevated bmi-1 expression is associated with dysplastic cell transformation during oral carcinogenesis and is required for cancer cell replication and survival Br J Cancer 96 2007 126 133 (Pubitemid 46094649)
39. I. Guney, S. Wu, and J.M. Sedivy Reduced c-myc signaling triggers telomere-independent senescence by regulating bmi-1 and p16(INK4a) Proc Natl Acad Sci USA 103 2006 3645 3650 (Pubitemid 43376609)
40. L. Lo Muzio A possible role for the WNT-1 pathway in oral carcinogenesis Crit Rev Oral Biol Med 12 2001 152 165 (Pubitemid 32429281)
41. E. Macias, Y. Kim, P.L. Miliani de Marval, A. Klein-Szanto, and M.L. Rodriguez-Puebla Cdk2 deficiency decreases ras/CDK4-dependent malignant progression, but not myc-induced tumorigenesis Cancer Res 67 2007 9713 9720 (Pubitemid 47621218)
42. I.C. Paterson, V. Patel, J.R. Sandy, S.S. Prime, and W.A. Yeudall Effects of transforming growth factor beta-1 on growth-regulatory genes in tumour-derived human oral keratinocytes Br J Cancer 72 1995 922 927
43. Y.J. Chen, S.C. Lin, T. Kao, C.S. Chang, P.S. Hong, and T.M. Shieh Genome-wide profiling of oral squamous cell carcinoma J Pathol 204 2004 326 332 (Pubitemid 39430093)
44. T.S. Wong, X.B. Liu, B.Y. Wong, R.W. Ng, A.P. Yuen, and W.I. Wei Mature miR-184 as potential oncogenic microRNA of squamous cell carcinoma of tongue Clin Cancer Res 14 2008 2588 2592
45. W. Kakuguchi, T. Kitamura, T. Kuroshima, M. Ishikawa, Y. Kitagawa, and Y. Totsuka HuR knockdown changes the oncogenic potential of oral cancer cells Mol Cancer Res 8 2010 520 528
46. E. Vairaktaris, G. Kalokerinos, L. Goutzanis, S. Spyridonidou, S. Vassiliou, and S. Derka Diabetes alters expression of p53 and c-myc in different stages of oral oncogenesis Anticancer Res 27 2007 1465 1473 (Pubitemid 46807224)
47. K. Freier, S. Joos, C. Flechtenmacher, F. Devens, A. Benner, and F.X. Bosch Tissue microarray analysis reveals site-specific prevalence of oncogene amplifications in head and neck squamous cell carcinoma Cancer Res 63 2003 1179 1182 (Pubitemid 36348691)
48. B. Popovic, B. Jekic, I. Novakovic, L. Lukovic, V. Konstantinovic, and M. Babic Cancer genes alterations and HPV infection in oral squamous cell carcinoma Int J Oral Maxillofac Surg 39 2010 909 915
49. K. Tadokoro, M. Ueda, T. Ohshima, K. Fujita, K. Rikimaru, and N. Takahashi Activation of oncogenes in human oral cancer cells: a novel codon 13 mutation of c-H-ras-1 and concurrent amplifications of c-erbB-1 and c-myc Oncogene 4 1989 499 505 (Pubitemid 19109765)
50. K. Kim, E. Akoto-Amanfu, H.M. Cherrick, and N.H. Park Anchorage-independent growth and the expression of cellular proto-oncogenes in normal human epidermal keratinocytes and in human squamous cell carcinoma cell lines Oral Surg Oral Med Oral Pathol 71 1991 303 311
51. Y. Abiko, J. Arai, J. Mitamura, and T. Kaku Alteration of proto-oncogenes during apoptosis in the oral squamous cell carcinoma cell line, SAS, induced by staurosporine Cancer Lett 118 1997 101 107 (Pubitemid 27397230)
52. B.H. Haughey, D.D. von Hoff, B.E. Windle, G.M. Wahl, and P.M. Mock C-myc oncogene copy number in squamous carcinoma of the head and neck Am J Otolaryngol 13 1992 168 171
53. M. Srinivasan, and S.D. Jewell Quantitative estimation of PCNA, c-myc, EGFR and TGF-alpha in oral submucous fibrosis - an immunohistochemical study Oral Oncol 37 2001 461 467 (Pubitemid 32480284)
54. J.A. Squire, J. Bayani, C. Luk, L. Unwin, J. Tokunaga, and C. MacMillan Molecular cytogenetic analysis of head and neck squamous cell carcinoma: by comparative genomic hybridization, spectral karyotyping, and expression array analysis Head Neck 24 2002 874 887
55. K. Freier, C. Schwaenen, C. Sticht, C. Flechtenmacher, J. Muhling, and C. Hofele Recurrent FGFR1 amplification and high FGFR1 protein expression in oral squamous cell carcinoma (OSCC) Oral Oncol 43 2007 60 66 (Pubitemid 46162249)
56. D. Saranath, L.T. Bhoite, and M.G. Deo Molecular lesions in human oral cancer: the indian scene Eur J Cancer B Oral Oncol 29B 1993 107 112 (Pubitemid 23156614)