Native low density lipoprotein induces pancreaticβ cell apoptosis through generating excess reactive oxygen species

Lipids in Health and Disease

Volumn 10, Issue , 2011, Pages

  Lu, Xiuli ^a   Liu, Jianli ^a   Cao, Xiangyu ^a   Hou, Xiao ^a   Wang, Xude ^a   Zhao, Chenguang ^a   Wang, Youliang ^a   Li, Yang ^a   Seo, Hisao ^b   Gao, Bing ^c  

^a LIAONING UNIVERSITY   (China)

^b CHUBU UNIVERSITY   (Japan)

^c SHENYANG MEDICAL COLLEGE   (China)

Author keywords

apoptosis; LDLS; MIN6; ROS

Indexed keywords

AGAROSE; CASPASE 3; GLUTATHIONE; LOW DENSITY LIPOPROTEIN; PROTEIN P53; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; ANTIOXIDANT; CASP3 PROTEIN, MOUSE; CHOLESTEROL; OXIDIZED LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL COUNT; CELL DEATH; CELL PROTECTION; CHOLESTEROL BLOOD LEVEL; DNA DAMAGE; ELECTROPHORESIS; ENZYME ACTIVATION; IN VITRO STUDY; LIPID DIET; LIPID PEROXIDATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CELL LINE; DNA FRAGMENTATION; DRUG EFFECT; HUMAN; METABOLISM; PHYSIOLOGY;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CASPASE 3; CELL LINE; CHOLESTEROL; DNA FRAGMENTATION; GLUTATHIONE; HUMANS; INSULIN-SECRETING CELLS; LIPOPROTEINS, LDL; MICE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 79960690476     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-10-123     Document Type: Article

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