Prostaglandin E2 EP1 receptor inhibition fails to provide neuroprotection in surgically induced brain-injured mice

Acta Neurochirurgica, Supplementum

Volumn , Issue 111, 2011, Pages 277-281

  Khatibi, Nikan H ^a   Jadhav, Vikram ^b   Matus, Brenden ^b   Fathali, Nancy ^b   Martin, Robert ^a   Applegate, Richard ^a   Tang, Jiping ^b   Zhang, John H ^a,b  

^a LOMA LINDA UNIVERSITY MEDICAL CENTER   (United States)

^b LOMA LINDA UNIVERSITY   (United States)

Author keywords

EP1 Receptor; Neurosurgery; SC 51089; Surgically induced brain injury (SBI)

Indexed keywords

PROSTAGLANDIN E RECEPTOR 1; PROSTAGLANDIN E2; PROSTAGLANDIN RECEPTOR BLOCKING AGENT; SC 51089; UNCLASSIFIED DRUG; HYDRAZINE DERIVATIVE; NEUROPROTECTIVE AGENT; OXAZEPINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; BRAIN EDEMA; BRAIN INJURY; CELL DEATH; CONFERENCE PAPER; CONTROLLED STUDY; CRANIOTOMY; DRUG DOSE COMPARISON; DRUG MEGADOSE; ENZYME INHIBITION; LOW DRUG DOSE; MALE; MOUSE; NEUROPROTECTION; NEUROPSYCHOLOGICAL TEST; NONHUMAN; SINGLE DRUG DOSE; ANIMAL; ARTICLE; DISEASE MODEL; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; HEMISPHERIC DOMINANCE; NEUROLOGIC DISEASE; NEUROSURGERY; TIME; TREATMENT FAILURE;

ANIMALS; BRAIN EDEMA; BRAIN INJURIES; CELL DEATH; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FUNCTIONAL LATERALITY; HYDRAZINES; MALE; MICE; NERVOUS SYSTEM DISEASES; NEUROPROTECTIVE AGENTS; NEUROSURGICAL PROCEDURES; OXAZEPINES; RECEPTORS, PROSTAGLANDIN E, EP1 SUBTYPE; TIME FACTORS; TREATMENT FAILURE;

EID: 79960682731     PISSN: 00651419     EISSN: 00016268     Source Type: Book Series    
DOI: 10.1007/978-3-7091-0693-8_46     Document Type: Conference Paper

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