Immunity to pneumococcal surface proteins in children with community-acquired pneumonia: A distinct pattern of responses to pneumococcal choline-binding protein A

Clinical Microbiology and Infection

Volumn 17, Issue 8, 2011, Pages 1232-1238

  Posfay Barbe, K M ^a   Galetto Lacour, A ^b   Grillet, S ^a   Ochs, M M ^c   Brookes, R H ^c   Kraehenbuhl, J D ^d   Cevey Macherel, M ^d   Gehri, M ^d   Gervaix, A ^b   Siegrist, C A ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^c Sanofi Pasteur   (Canada)

^d LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Antibodies; Diagnosis; Pneumococcus; Pneumonia; Surface proteins

Indexed keywords

BACTERIUM ANTIBODY; IMMUNOGLOBULIN G; LYTB PROTEIN; PNEUMOCOCCAL CHOLINE BINDING PROTEIN A; PNEUMOCOCCAL HISTIDINE TRIAD D PROTEIN; PNEUMOCOCCAL HISTIDINE TRIAD E PROTEIN; PNEUMOLYSIN ANTIBODY; PROTEIN ANTIBODY; STREPTOCOCCUS ANTIGEN; UNCLASSIFIED DRUG;

ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ANTIBODY TITER; ANTIGEN RECOGNITION; ARTICLE; BACTERIAL IMMUNITY; BACTERIUM CULTURE; CHILD; COMMUNITY ACQUIRED PNEUMONIA; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; HUMAN; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PREDICTIVE VALUE; PRESCHOOL CHILD; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SERODIAGNOSIS; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE;

STREPTOCOCCUS PNEUMONIAE;

EID: 79960669547     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1111/j.1469-0691.2010.03389.x     Document Type: Article

References (31)

1. Mulholland K. Childhood pneumonia mortality-a permanent global emergency. Lancet 2007; 370: 285-289.
2. Pio A. Standard case management of pneumonia in children in developing countries: the cornerstone of the acute respiratory infection programme. Bull WHO 2003; 81: 298-300.
3. Dowell SF, Garman RL, Liu G, Levine OS, Yang YH. Evaluation of Binax NOW, an assay for the detection of pneumococcal antigen in urine samples, performed among pediatric patients. Clin Infect Dis 2001; 32: 824-825.
4. Juven T, Mertsola J, Waris M et al. Etiology of community-acquired pneumonia in 254 hospitalized children. Pediatr Infect Dis J 2000; 19: 293-298.
5. Michelow IC, Olsen K, Lozano J et al. Epidemiology and clinical characteristics of community-acquired pneumonia in hospitalized children. Pediatrics 2004; 113: 701-707.
6. Korppi M, Leinonen M, Ruuskanen O. Pneumococcal serology in children's respiratory infections. Eur J Clin Microbiol Infect Dis 2008; 27: 167-175.
7. Hirst RA, Kadioglu A, O'Callaghan C, Andrew PW. The role of pneumolysin in pneumococcal pneumonia and meningitis. Clin Exp Immunol 2004; 138: 195-201.
8. Michelow IC, Lozano J, Olsen K et al. Diagnosis of Streptococcus pneumoniae lower respiratory infection in hospitalized children by culture, polymerase chain reaction, serological testing, and urinary antigen detection. Clin Infect Dis 2002; 34: E1-E11.
9. Scott JA, Obiero J, Hall AJ, Marsh K. Validation of immunoglobulin G enzyme-linked immunosorbent assay for antibodies to pneumococcal surface adhesin A in the diagnosis of pneumococcal pneumonia among adults in Kenya. J Infect Dis 2002; 186: 220-226.
10. Scott JA, Mlacha Z, Nyiro J et al. Diagnosis of invasive pneumococcal disease among children in Kenya with enzyme-linked immunosorbent assay for immunoglobulin G antibodies to pneumococcal surface adhesin A. Clin Diagn Lab Immunol 2005; 12: 1195-1201.
11. Giefing C, Meinke AL, Hanner M et al. Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies. J Exp Med 2008; 205: 117-131.
12. Jefferies JM, Johnston CH, Kirkham LA et al. Presence of nonhemolytic pneumolysin in serotypes of Streptococcus pneumoniae associated with disease outbreaks. J Infect Dis 2007; 196: 936-944.
13. Wizemann TM, Heinrichs JH, Adamou JE et al. Use of a whole genome approach to identify vaccine molecules affording protection against Streptococcus pneumoniae infection. Infect Immun 2001; 69: 1593-1598.
14. Adamou JE, Heinrichs JH, Erwin AL et al. Identification and characterization of a novel family of pneumococcal proteins that are protective against sepsis. Infect Immun 2001; 69: 949-958.
15. De Las Rivas B, Garcia JL, Lopez R, Garcia P. Purification and polar localization of pneumococcal LytB, a putative endo-beta-N-acetylglucosaminidase: the chain-dispersing murein hydrolase. J Bacteriol 2002; 184: 4988-5000.
16. Rosenow C, Ryan P, Weiser JN et al. Contribution of novel choline-binding proteins to adherence, colonization and immunogenicity of Streptococcus pneumoniae. Mol Microbiol 1997; 25: 819-829.
17. Cevey-Macherel M, Galetto-Lacour A, Gervaix A et al. Etiology of community-acquired pneumonia in hospitalized children based on WHO clinical guidelines. Eur J Pediatr 2009; 168: 1429-1436.
18. World Health Organization. Acute respiratory infections in children: case management in small hospitals in developing countries, 5th edn. Geneva: WHO, 1990.
19. Jalonen E, Paton JC, Koskela M, Kerttula Y, Leinonen M. Measurement of antibody responses to pneumolysin-a promising method for the presumptive aetiological diagnosis of pneumococcal pneumonia. J Infect 1989; 19: 127-134.
20. Nohynek H, Eskola J, Kleemola M, Jalonen E, Saikku P, Leinonen M. Bacterial antibody assays in the diagnosis of acute lower respiratory tract infection in children. Pediatr Infect Dis J 1995; 14: 478-484.
21. Claesson BA, Trollfors B, Brolin I et al. Etiology of community-acquired pneumonia in children based on antibody responses to bacterial and viral antigens. Pediatr Infect Dis J 1989; 8: 856-862.
22. Goldblatt D, Hussain M, Andrews N et al. Antibody responses to nasopharyngeal carriage of Streptococcus pneumoniae in adults: a longitudinal household study. J Infect Dis 2005; 192: 387-393.
23. Holmlund E, Quiambao B, Ollgren J, Nohynek H, Kayhty H. Development of natural antibodies to pneumococcal surface protein A, pneumococcal surface adhesin A and pneumolysin in Filipino pregnant women and their infants in relation to pneumococcal carriage. Vaccine 2006; 24: 57-65.
24. Rapola S, Kilpi T, Lahdenkari M, Makela PH, Kayhty H. Antibody response to the pneumococcal proteins pneumococcal surface adhesin A and pneumolysin in children with acute otitis media. Pediatr Infect Dis J 2001; 20: 482-487.
25. Nakayama E, Hasegawa K, Morozumi M et al. Rapid optimization of antimicrobial chemotherapy given to pediatric patients with community-acquired pneumonia using PCR techniques with serology and standard culture. J Infect Chemother 2007; 13: 305-313.
26. Ramsey BW, Marcuse EK, Foy HM et al. Use of bacterial antigen detection in the diagnosis of pediatric lower respiratory tract infections. Pediatrics 1986; 78: 1-9.
27. Harrell LJ, Sharps SK, Bean RA, Reller LB. Genetic relatedness of Streptococcus pneumoniae isolates from paired blood and respiratory specimens. J Clin Microbiol 2007; 45: 2017-2019.
28. Sanchez-Beato AR, Lopez R, Garcia JL. Molecular characterization of PcpA: a novel choline-binding protein of Streptococcus pneumoniae. FEMS Microbiol Lett 1998; 164: 207-214.
29. Johnston JW, Briles DE, Myers LE, Hollingshead SK. Mn2+-dependent regulation of multiple genes in Streptococcus pneumoniae through PsaR and the resultant impact on virulence. Infect Immun 2006; 74: 1171-1180.
30. Scheuhammer AM, Cherian MG. Binding of manganese in human and rat plasma. Biochim Biophys Acta 1985; 840: 163-169.
31. Chicharro JL, Serrano V, Urena R et al. Trace elements and electrolytes in human resting mixed saliva after exercise. Br J Sports Med 1999; 33: 204-207.