Serum major-histocompatibility-complex class I-related chain a antibody detection for the evaluation of graft dysfunction in renal allograft recipients

Chinese Medical Journal

Volumn 124, Issue 14, 2011, Pages 2127-2131

  Zhang, Ming ^a   Lu, Fu Ming ^a   Qu, Lian Xi ^a   He, Jun ^b   Yuan, Xiao Niao ^b   Gu, Yong ^a  

^a FUDAN UNIVERSITY   (China)

^b SOOCHOW UNIVERSITY   (China)

Author keywords

Acute rejection; Anti HLA antibodies; Major histocompatibility complex class I related chain A antibody; Renal transplantation

Indexed keywords

BASILIXIMAB; COMPLEMENT COMPONENT C4D; CYCLOSPORIN; DACLIZUMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; HLA A ANTIGEN; HLA ANTIBODY; MYCOPHENOLIC ACID; PREDNISONE; TACROLIMUS; THYMOCYTE ANTIBODY;

ACUTE GRAFT REJECTION; ADULT; ANTIBODY PRODUCTION; ANTIBODY SCREENING; ANTIBODY SPECIFICITY; ARTICLE; CLINICAL EVALUATION; COMPLEMENT DEPENDENT CYTOTOXICITY; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; GLOMERULUS FILTRATION RATE; GRAFT RECIPIENT; GRAFT SURVIVAL; HISTOPATHOLOGY; HLA TYPING; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY ALLOGRAFT REJECTION; KIDNEY BIOPSY; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PROTEIN BLOOD LEVEL; RISK ASSESSMENT;

ADULT; ANTIBODIES; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; TRANSPLANTATION, HOMOLOGOUS;

EID: 79960662797     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2011.14.009     Document Type: Article

References (27)

1. Opelz G. Non-HLA-transplantation immunity revealed by lymphocytotoxic antibodies. Lancet 2005; 365: 1570-1576.
2. Worthington JE, McEwen A, McWilliam LJ, Picton MJ, Martin S. Association between C4d staining in renal transplant biopsies, production of donor-specific HLA antibodies, and graft outcome. Transplantation 2007; 83: 398-403.
3. Zou Y, Stastny P, Susal C, Dohler B, Opelz G. Antibodies against MICA antigens and kidney-transplant rejection. N Engl J Med 2007; 357: 1293-1300.
4. Mizutani K, Terasaki P, Bignon JD, Hourmant M, Cesbron-Gautier A, Shih RNJ, et al. Association of kidney transplant failure and antibodies against MICA. Hum Immunol 2006; 67: 683-691.
5. Zwirner NW, Marcos CY, Mirbaha F, Zou Y, Stastny P. Identification of MICA as a new polymorphic alloantigen recognized by antibodies in sera of organ transplant recipients. Hum Immunol 2000; 61: 917-924.
6. Zwirner NW, Dole K, Stastny P. Differential surface expression of MICA by endothelial cells, fibroblasts, keratinocytes, and monocytes. Hum Immunol 1999; 60: 323-330.
7. Lederer SR, Kluth-Pepper B, Schneeberger H, Albert E, Land W, Feucht HE. Impact of humoralalloreactivity early after transplantation on the long-term survival of renal allografts. Kidney Int 2001; 59: 334-341.
8. Herzenberg AM, Gill JS, Djurdjev O, Magil AB. C4d deposition in acute rejection: an independent long-term prognostic factor. J Am Soc Nephrol 2002; 13: 234-241.
9. Mauiyyedi S, Crespo M, Collins AB, Schneeberger EE, Pascual MA, Saidman SL, et al. Acute humoral rejection in kidney transplantation: II. Morphology, immunopathology, and pathologic classification. J Am Soc Nephrol 2002; 13: 779-787.
10. Zou Y, Heinemann FM, Grosse-Wilde H, Sireci G, Wang Z, Lavingia B, et al. Detection of anti-MICA antibodies in patients awaiting kidney transplantation, during the post-transplant course, and in eluates from rejected kidney allografts by Luminex flow cytometry. Hum Immunol 2006; 67: 230-237.
11. Mizutani K, Terasaki P, Rosen A, Esquenazi V, Miller J, Shih RN, et al. Serial ten-year follow-up of HLA and MICA antibody production prior to kidney graft failure. Am J Transplant 2005; 5: 2265-2272.
12. Ruggeri L, Mancusi A, Burchielli E, Aversa F, Martelli MF, Velardi A. Natural killer cell alloreactivity in allogeneic hematopoietic transplantation. Curr Opin Oncol 2007; 19: 142-147
13. Trpkov K, Campbell P, Pazderka F, Cockfield S, Solez K, Halloran PF. Pathologic features of acute renal allograft rejection associated with donor-specific antibody. Analysis using the Banff grading scheme. Transplantation 1996; 61: 1586-1592.
14. Terasaki PI. Humoral theory of transplantation. Am J Transplant 2003; 3: 665-673.
15. Harmer AW, Koffman CG, Heads AJ, Vaughan RW. Sensitization to HLA antigens occurs in 95% of primary renal transplant rejections. Transplant Proc 1995; 27: 666-667.
16. Lee PC, Terasaki PI, Takemoto SK, Lee PH, Hung CJ, Chen YL, et al. All chronic rejection failures of kidney transplants were preceded by the development of HLA antibodies. Transplantation 2002; 74: 1192-1194.
17. El-Awar N, Terasaki PI, Lazda V, Nikaein A, Manning C, Arnold AN. Almost all patients who are waiting for a regraft of a kidney transplant have anti HLA antibodies. Transplant Proc 2002; 34: 2531-2532.
18. Worthington JE, Martin S, Dyer PA, Jahson RW. An association between post-transplant antibody production and renal transplant rejection. Transplant Proc 2001; 33: 475-476.
19. Crespo M, Pascual M, Tolkoff-Rubin N, Mauiyyedi S, Collins AB, Fitzpatrick D, et al. Acute humoral rejection in renal allograft recipients: I. Incidence, serology and clinical characteristics. Transplantation 2001; 71: 652-658.
20. Terasaki PI, Ozawa M. Predicting kidney graft failure by HLA antibodies: a prospective trial. Am J Transplant 2004; 4: 438-443.
21. Zhang Q, Liang LW, Gjertson DW, Lassman C, Wilkinson AH, Kendrick E, et al. Development of post-transplant anti-donor HLA antibodies is associated with acute humoral rejection and early graft dysfunction. Transplantation 2005; 79: 591-598.
22. Zou Y, Mirbaha F, Lazaro A, Zhang Y, Lavingia B, Stastny P. MICA is a target for complement-dependent cytotoxicity with mouse monoclonal antibodies and human alloantibodies. Hum Immunol 2002; 63: 30-39.
23. Hankey KG, Drachenberg CB, Papadimitriou JC, Klassen DK, Philosophe B, Bartlett ST, et al. MIC expression in renal and pancreatic allografts. Transplantation 2002; 73: 304-306.
24. Quiroga I, Salio M, Koo DD, Cerundolo L, Shepherd D, Cerundolo V, et al. Expression of MHC class I-related chain B (MICB) molecules on renal transplant biopsies. Transplantation 2006; 81: 1196-1203.
25. Quiroga I, Salio M, Koo DD, Cerundolo L, Shepherd D, Cerundolo V, et al. Frequency and clinical implications of the development of donor-specific and non donor-specific HLA antibodies after kidney transplantation. J Am Soc Nephrol 2005; 16: 2804-2812.
26. Terasaki PI, Cai J. Humoral theory of transplantation: further evidence. Curr Opin Immunol 2005; 17: 541-545.
27. Terasaki PI, Ozawa M. Predictive value of HLA antibodies and serum creatinine in chronic rejection: results of a 2-year prospective trial. Transplantion 2005; 80: 1194-1197.