Association of thymidylate synthase enhancer region polymorphisms with thymidylate synthase activity in vivo

Pharmacogenomics Journal

Volumn 11, Issue 4, 2011, Pages 307-314

  De Bock, C E ^a,b   Garg, M B ^b,c   Scott, N ^b,d   Sakoff, J A ^b,c   Scorgie, F E ^b,c   Ackland, S P ^b,c,d   Lincz, L F ^b,c,d  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b HUNTER MEDICAL RESEARCH INSTITUTE   (Australia)

^c CALVARY MATER NEWCASTLE HOSPITAL   (Australia)

^d UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

dUrd; luciferase; polymorphism; promoter; TSER; USF 1

Indexed keywords

LUCIFERASE; THYMIDYLATE SYNTHASE;

ADULT; ARTICLE; CANCER CELL; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; ENHANCER REGION; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; FEMALE; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN CELL; IN VIVO STUDY; KIDNEY FUNCTION; MALE; PRIORITY JOURNAL; PROMOTER REGION; VARIABLE NUMBER OF TANDEM REPEAT;

AGED; ANALYSIS OF VARIANCE; ANTIMETABOLITES, ANTINEOPLASTIC; COHORT STUDIES; COLORECTAL NEOPLASMS; DEOXYURIDINE; ENHANCER ELEMENTS, GENETIC; FEMALE; FLUOROURACIL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, REPORTER; GENOTYPE; HCT116 CELLS; HELA CELLS; HUMANS; MALE; MIDDLE AGED; NEW SOUTH WALES; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; TANDEM REPEAT SEQUENCES; THYMIDYLATE SYNTHASE; TRANSFECTION; UPSTREAM STIMULATORY FACTORS;

EID: 79960624456     PISSN: 1470269X     EISSN: 14731150     Source Type: Journal    
DOI: 10.1038/tpj.2010.43     Document Type: Article

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