Acute exacerbations in COPD and their control with oral immunization with non-typeable Haemophilus influenzae

Frontiers in Immunology

Volumn 2, Issue MAR, 2011, Pages

  Clancy, Robert L ^a,b   Dunkley, Margaret ^a  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b JOHN HUNTER HOSPITAL   (Australia)

Author keywords

Airways; Chronic obstructive pulmonary disease; Copd; Emphysema; Respiratory

Indexed keywords

EID: 79960608453     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2011.00007     Document Type: Article

References (36)

1. Bandi, V., Apicella, M. A., Mason, E., Murphy, T. F., Siddiqi, A., Atmar, R. L., and Greenberg, S. V. (2001). Nontypeable Haemophilus influenzae in the lower respiratory tract of patients with chronic bronchitis. Am. J. Respir. Crit. Care Med. 164, 2114-2119.
2. Barnes, P. J. (2008). Immunology of asthma and chronic obstructive pulmonary disease. Nat. Rev. Immunol. 8, 183-192.
3. Briscoe, W. A., and Nash, E. S. (1965). The slow space in chronic obstructive pulmonary disease. Ann. N. Y. Acad. Sci. 121, 706-722.
4. Butt, H. L., Clancy, R. L., Cripps, A. W., Murree-Allen, K., Saunders, N. A., Sutherland, D. C., and Hensley, M. J. (1990). Bacterial colonisation of the respiratory tract in chronic bronchitis. Aust. N. Z. J. Med. 20, 35-38.
5. Clancy, R. L., Cripps, A. W., Murree-Allen, K., Yeung, S., and Engel, M. (1985). Oral immunisation with killed Haemophilus influenzae for protection against acute bronchitis in chronic obstructive lung disease. Lancet 2, 1395-1397.
6. Clancy, R. L., Pang, G., Dunkley, M. L., Taylor, D., and Cripps, A. W. (1995). Acute on chronic bronchitis: a model of mucosal immunology. Immunol. Cell Biol. 73, 414-417.
7. Clancy, R. L., Cripps, A. W., and Gebski, V. (1990). Protection against recurrent acute bronchitis following oral immunization with killed Haemophilus influenzae. Med. J. Aust. 152, 413-416.
8. Clancy,R. L.,and Dunkley,M. L. (2010). Oral non-typeable Haemophilus influenzae enhances physiological mechanism of airways protection. Clin. Exp. Immunol. 161, 127-133.
9. Dubin, P. J., McAllister, F., and Kolls, J. K. (2007). Is cystic fibrosis a TH17 disease? Inflamm. Res. 56, 221-227.
10. Dunkley, M., and Clancy, R. L. (1997). "A rodent model of concurrent respiratory infection with influenza virus and Gram-negative bacteria: synergistic infection and protection by oral immunization." In Mucosal Solutions: Advances in Mucosal Immunology,Vol. 1, eds A. J. Husband,K.W. Beagley,R. L. Clancy, and A. W. Cripps (Sydney: University of Sydney Press), 279-288.
11. Dunkley, M., Pabst, R., and Cripps, A. (1995). An important role for intestinally-derived T cells in respiratory defence. Immunol. Today 16, 231-236.
12. Dunkley, M. L., Clancy, R. L., and Cripps, A. W. (1994). A role for CD4+ T cells from orally immunized rats in enhanced clearance of Pseudomonas aeruginosa from the lung. Immunology 83, 362-369.
13. Fletcher, C., and Peto, R. (1977). The natural history of chronic airflow obstruction. Br. Med. J. 1, 1645-1648.
14. Foxwell, A. R., Cripps, A. W., and Dear, K. B. G. (2006). Haemophilus influenzae oral whole cell vaccination for preventing acute exacerbations of chronic bronchitis. Cochrane Database Syst. Rev. 4, CD001958.
15. Iwata, M., Hirakiyama, A., Eshima, Y., Kagechika, H., Kato, C., and Song, S. Y. (2004). Retinoic acid imprints gut-homing specificity on T cells. Immunity 21, 257-238.
16. Khader, S. A., Gaffen, S. L., and Kolls, J. K. (2009). Th17 cells at the crossroads of innate and adaptive immunity against infectious diseases at the mucosa. Mucosal Immunol. 5, 403-411.
17. Kraft, M. (2006). Asthma and chronic obstructive pulmonary disease exhibit common origins in any country! Am. J. Respir. Crit. Care Med. 174, 238-240.
18. Lehmann, D., Coakley, K. J., Coakley, C. A., Spooner, V., Montgomery, J.M., Michael, A., Riley, I. D., Smith, T., Clancy, R. L., and Cripps, A. W. (1991). Reduction in the incidence of acute bronchitis by an oral Haemophilus influenzae vaccine in patients with chronic bronchitis in the Highlands of Papua New Guinea. Am. Rev. Respir. Dis. 144, 324-330.
19. May, J. R. (1953). The bacteriology of chronic bronchitis. Lancet 2, 534-537.
20. Otczyk, D., and Cripps, A. (2010). Mucosal immunisation: a realistic alternative. Hum. Vaccin. 6, 1-29.
21. Pang, G., Ortega, M., Zighang, R., Reeves, G., and Clancy, R. L. (1997). Autocrine modulation of IL-8 production by sputum neutrophils in chronic bronchial sepsis. Am. J. Respir. Crit. Care Med. 155, 726-731.
22. Petty,T. L. (2006). The history of COPD. Int. J. Chron. Obstruct. Pulmon. Dis. 1, 3-14.
23. Qimron, U., Paul, L., Bar-Haim, E., Bloushtain, N., Eisenbach, L., Staats, H.F., and Porgador, A. (2004). Nonreplicating mucosal and systematic vaccines: quantitative and qualitative differences in the Ag-specific CD8(+) T cell population in different tissues. Vaccine 22, 1390-1394.
24. Sethi, S., and Murphy, T. F. (2008). Infection in the pathogenesis and course of chronic obstructive pulmonary disease. N.Engl.J.Med.359, 2355-2365.
25. Sethi, S., Sethi, R., Eschberger, K., Lobbions, P., Cai, X., Grant, B. J. B., and Murphy, T. F. (2007). Airway bacterial concentrations and exacerbations of chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 176, 356-361.
26. Sethi, S.,Wrona, C., Eschberger, K., Lobbins, P., Cai, X., Grant, B. J. B., and Murphy, T. F. (2008). Inflammatory profile of new bacterial strain exacerbations of chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 177, 491-497.
27. Shan, M., Cheng, H. F., Song, L. Z., Roberts, L., Green, L., Hacken-Bitar, J., Huh, J., Bakaeen, S., Coxson, H. O., Storness-Bliss, C., Ramchandani, M., Lee, S. H., Corry, D., and Kheradmand, F. (2009). Lung myeloid dendritic cells coordinately induce Th1 and Th17 responses in human emphysema. Sci. Transl. Med. 1.4, 1-9.
28. Tager, I., and Speizer, F. E. (1975). Role of infection in chronic bronchitis. N. Engl.J.Med.292, 563-571.
29. Tandon, M. K., and Gebski, V. (1991). A controlled trial of a killed Haemophilus influenzae vaccine for prevention of acute exacerbations of chronic bronchitis. Aust. N. Z. J. Med. 21, 427-432.
30. Tandon, M. K., Phillips, M., Waterer, G., Dunkley, M. L., Coman, P., and Clancy, R. L. (2010). Oral immunotherapy with inactivated nontypeable Haemophilus influenzae reduces severity of acute exacerbations in severe COPD. Chest 137, 805-811.
31. Taylor, D. C., Cripps, A. W., and Clancy, R. L. (1990). Inhibition of adhesion of Haemophilus influenzae to buccal cells by respiratory secretions. Immunol. Cell Biol. 68, 335-342.
32. Wallace, F. J., Clancy, R. L., and Cripps, A. W. (1989). An animal model demonstration of enhanced clearance of nontypeable Haemophilus influenzae from the respiratory tract after antigen stimulation of gut associated lymphoid tissue. Am. Rev. Respir. Dis. 140, 311-316.
33. Wallace, F. J., Clancy, R. L., and Cripps, A. W. (1990). "Haemophilus influenzae immunity in the respiratory tract." In Advances in Mucosal Immunology, eds T. T. MacDonald, S. J. Challacombe, and P. W. Bland (London: Kluwer Academic Publishers), 859-860.
34. Wallace, F. J., Cripps, A. W., Clancy, R. L., Husband, A. J., and Witt, C. S. (1991). A role for intestinal T lymphocytes in bronchus mucosal immunity. Immunology 74, 68-73.
35. Wedzicha, J. A., and Seemungal, T. A. R. (2007). COPD exacerbations: defining their cause and prevention. Lancet 370, 786-796.
36. Xu, B., Wagner, N., Pham, L. N., Magno, V., Shan, Z., Butcher, E. C., and Michie, S. A. (2003). Lymphocyte homing to bronchus-associated lymphoid tissue (BALT) is mediated by L-selectin/PNAd, alpha4beta1 integrin/VCAM-1 and LFA-1 adhesion pathways. J. Exp. Med. 197, 1255-1267.