Total white blood cell count is associated with the presence, severity and extent of coronary atherosclerosis detected by dual-source multislice computed tomographic coronary angiography

Cardiology Journal

Volumn 18, Issue 4, 2011, Pages 371-377

  Ateş, Ahmet Hakan ^a   Canpolat, Uǧur ^b   Yorgun, Hikmet ^c   Kaya, Ergun Bariş ^b   Sunman, Hamza ^b   Demiri, Edis ^b   Taher, Ali ^b   Hazirolan, Tuncay ^b   Aytemir, Kudret ^b   Tokgözoǧlu, Lale ^b   Kabakçi, Giray ^b   Oto, Ali ^b  

^a Sinop State Hospital   (Turkey)

^b HACETTEPE UNIVERSITY   (Turkey)

^c Polatli Duatepe State Hospital   (Turkey)

Author keywords

Computed tomography; Coronary atherosclerosis; Leukocytosis

Indexed keywords

ADULT; ANGIOCARDIOGRAPHY; ARTICLE; ATHEROSCLEROTIC PLAQUE; CARDIOVASCULAR RISK; CLINICAL ASSESSMENT; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CROSS-SECTIONAL STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MULTIDETECTOR COMPUTED TOMOGRAPHY; PREDICTION; SMOKING HABIT;

AGED; CALCINOSIS; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; INFLAMMATION; LEUKOCYTE COUNT; LOGISTIC MODELS; MALE; MIDDLE AGED; ODDS RATIO; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RISK ASSESSMENT; RISK FACTORS; SEVERITY OF ILLNESS INDEX; TOMOGRAPHY, X-RAY COMPUTED; TURKEY;

EID: 79960604427     PISSN: 18975593     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Murray CJ, Lopez AD. Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. Lancet, 1997; 349: 1436-1442.
2. Ross R. Atherosclerosis: An inflammatory disease. N Engl J Med, 1999; 340: 115-126.
3. Madjid M, Awan I, Willerson JT, Casscells SW. Leukocyte count and coronary heart disease: Implications for risk assessment. J Am Coll Cardiol, 2004; 44: 1945-1956.
4. Danesh J, Collins R, Appleby P, Peto R. Association of fibrino-gen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: Meta-analyses of prospective studies. JAMA, 1998; 279: 1477-1482.
5. Kostis JB, Turkevich D, Sharp J. Association between leukocyte count and the presence and extent of coronary atherosclerosis as determined by coronary arteriography. Am J Cardiol, 1984; 53: 997-999.
6. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care, 1997; 20: 1183-1197.
7. Grundy SM, Pasternak R, Greenland P, Smith S Jr, Fuster V. AHA/ACC scientific statement: Assessment of cardiovascular risk by use of multiple-risk-factor assessment equations: A statement for healthcare professionals from the American Heart Association and the American College of Cardiology. J Am Coll Cardiol, 1999; 34: 1348-1359.
8. Austen WG, Edwards JE, Frye RL et al. A reporting system on patients evaluated for coronary artery disease. Report of the Ad Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery, American Heart Association. Circulation, 1975; 51: 5-40.
9. Pundziute G, Schuijf JD, Jukema JW et al. Prognostic value of multislice computed tomography coronary angiography in patients with known or suspected coronary artery disease. J Am Coll Cardiol, 2007; 49: 62-70.
10. Prentice RL, Szatrowski TP, Fujikura T, Kato H, Mason MW, Hamilton HH. Leukocyte counts and coronary heart disease in a Japanese cohort. Am J Epidemiol, 1982; 116: 496-509.
11. Friedman GD, Klatsky AL, Siegelaub AB. The leukocyte count as a predictor of myocardial infarction. N Engl J Med, 1974; 290: 1275-1278.
12. Mehta J, Dinerman J, Mehta P et al. Neutrophil function in is-chemic heart disease. Circulation, 1989; 79: 549-556.
13. Phillips AN, Neaton JD, Cook DG, Grimm RH, Shaper AG. Leukocyte count and risk of major coronary heart disease events. Am J Epidemiol, 1992; 136: 59-70.
14. Zalokar JB, Richard JL, Claude JR. Leukocyte count, smoking, and myocardial infarction. N Engl J Med, 1981; 304: 465-468.
15. Kannel WB, Anderson K, Wilson PW. White blood cell count and cardiovascular disease. Insights from the Framingham Study. JAMA, 1992; 267: 1253-1256.
16. Gillum RF, Ingram DD, Makuc DM. White blood cell count, coronary heart disease, and death: The NHANES I Epidemio-logic Follow-up Study. Am Heart J, 1993; 125: 855-863.
17. Manttari M, Manninen V, Koskinen P et al. Leukocytes as a coronary risk factor in a dyslipidemic male population. Am Heart J, 1992; 123: 873-877.
18. Takeda Y, Suzuki S, Fukutomi T et al. Elevated white blood cell count as a risk factor of coronary artery disease: Inconsistency between forms of the disease. Jpn Heart J, 2003; 44: 201-211.
19. Libby P. Current concepts of the pathogenesis of the acute coronary syndromes. Circulation, 2001; 104: 365-372.
20. Moreno PR, Falk E, Palacios IF, Newell JB, Fuster V, Fallon JT. Macrophage infiltration in acute coronary syndromes. Implications for plaque rupture. Circulation, 1994; 90: 775-778.
21. Sabatine MS, Morrow DA, Cannon CP et al. Relationship between baseline white blood cell count and degree of coronary artery disease and mortality in patients with acute coronary syndromes: A TACTICS-TIMI 18 (Treat Angina with Aggrastat and determine Cost of Therapy with an Invasive or Conservative Strategy-Thrombolysis in Myocardial Infarction 18 trial) sub-study. J Am Coll Cardiol, 2002; 40: 1761-1768.
22. Loimaala A, Rontu R, Vuori I et al. Blood leukocyte count is a risk factor for intima-media thickening and subclinical carotid atherosclerosis in middle-aged men. Atherosclerosis, 2006; 188: 363-369.
23. Budoff MJ, Achenbach S, Blumenthal RS et al. Assessment of coronary artery disease by cardiac computed tomography: A scientific statement from the American Heart Association Committee on Cardiovascular Imaging and Intervention, Council on Cardiovascular Radiology and Intervention, and Committee on Cardiac Imaging, Council on Clinical Cardiology. Circulation, 2006; 114: 1761-1791.
24. Hoffmann U, Moselewski F, Nieman K et al. Noninvasive assessment of plaque morphology and composition in culprit and stable lesions in acute coronary syndrome and stable lesions in stable angina by multidetector computed tomography. J Am Coll Cardiol, 2006; 47: 1655-1662.
25. Matsumoto N, Sato Y, Yoda S et al. Prognostic value of non-obstructive CT low-dense coronary artery plaques detected by multislice computed tomography. Circ J, 2007; 71: 1898-1903.
26. Orakzai SH, Orakzai RH, Nasir K et al. Subclinical coronary atherosclerosis: racial profiling is necessary! Am Heart J, 2006; 152: 819-827.