Expanding the role of Drosha to the regulation of viral gene expression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 27, 2011, Pages 11229-11234

  Lin, Yao Tang ^a   Sullivan, Christopher S ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

cis regulation 3 UTR; Microprocessor

Indexed keywords

PROTEIN KAPOSIN B; RIBONUCLEASE; RIBONUCLEASE DROSHA; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; HUMAN HERPESVIRUS 8; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRUS GENE; VIRUS REPLICATION;

3' UNTRANSLATED REGIONS; BASE SEQUENCE; GENE EXPRESSION REGULATION, VIRAL; HEK293 CELLS; HERPESVIRUS 8, HUMAN; HUMANS; MICRORNAS; MODELS, BIOLOGICAL; RIBONUCLEASE III; RNA, VIRAL; VIRAL PROTEINS; VIRUS REPLICATION;

HUMAN HERPESVIRUS 8;

EID: 79960597294     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1105799108     Document Type: Article

References (31)

1. Liu Y, Wimmer E, Paul AV (2009) Cis-acting RNA elements in human and animal plusstrand RNA viruses. Biochim Biophys Acta 1789:495-517.
2. Lieberman PM (2008) Chromatin organization and virus gene expression. J Cell Physiol 216:295-302.
3. Yaniv M (2009) Small DNA tumour viruses and their contributions to our understanding of transcription control. Virology 384:369-374.
4. Boss IW, Renne R (2010) Viral miRNAs: Tools for immune evasion. Curr Opin Microbiol 13:540-545.
5. Skalsky RL, Cullen BR (2010) Viruses, microRNAs, and host interactions. Annu Rev Microbiol 64:123-141.
6. Sullivan CS (2008) New roles for large and small viral RNAs in evading host defences. Nat Rev Genet 9:503-507.
7. Grundhoff A, Sullivan CS (2011) Virus-encoded microRNAs. Virology 411:325-343.
8. Kim VN (2005) MicroRNA biogenesis: Coordinated cropping and dicing. Nat Rev Mol Cell Biol 6:376-385.
9. Han J, et al. (2009) Posttranscriptional crossregulation between Drosha and DGCR8. Cell 136(1):75-84.
10. Chong MM, et al. (2010) Canonical and alternate functions of the microRNA biogenesis machinery. Genes Dev 24:1951-1960.
11. Shenoy A, Blelloch R (2009) Genomic analysis suggests that mRNA destabilization by the microprocessor is specialized for the auto-regulation of Dgcr8. PLoS ONE 4:e6971.
12. Ganem D (2007) Kaposi's Sarcoma-associated Herpesvirus. Fields Virology, eds Knipe DM, Howley PM (Lippincott Williams & Wilkins, Philadelphia), 5th Ed.
13. Speck SH, Ganem D (2010) Viral latency and its regulation: Lessons from the gammaherpesviruses. Cell Host Microbe 8(1):100-115.
14. Sadler R, et al. (1999) A complex translational program generates multiple novel proteins from the latently expressed kaposin (K12) locus of Kaposi's sarcomaassociated herpesvirus. J Virol 73:5722-5730. (Pubitemid 29274858)
15. Chang PJ, et al. (2002) Open reading frame 50 protein of Kaposi's sarcoma-associated herpesvirus directly activates the viral PAN and K12 genes by binding to related response elements. J Virol 76:3168-3178.
16. Li H, Komatsu T, Dezube BJ, Kaye KM (2002) The Kaposi's sarcoma-associated herpesvirus K12 transcript from a primary effusion lymphoma contains complex repeat elements, is spliced, and initiates from a novel promoter. J Virol 76:11880-11888. (Pubitemid 35304288)
17. McCormick C, Ganem D (2005) The kaposin B protein of KSHV activates the p38/MK2 pathway and stabilizes cytokine mRNAs. Science 307:739-741. (Pubitemid 40194646)
18. Sullivan CS, Cullen BR (2009) Non-coding Regulatory RNAs of the DNA Tumor Viruses. DNA Tumor viruses, eds Damania B, Pipas JM (Springer Science, New York), pp 645-682.
19. Renne R, et al. (1996) Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture. Nat Med 2:342-346. (Pubitemid 26080656)
20. Grossmann C, Podgrabinska S, Skobe M, Ganem D (2006) Activation of NF-kappaB by the latent vFLIP gene of Kaposi's sarcoma-associated herpesvirus is required for the spindle shape of virus-infected endothelial cells and contributes to their proinflammatory phenotype. J Virol 80:7179-7185. (Pubitemid 44025214)
21. Abend JR, Uldrick T, Ziegelbauer JM (2010) Regulation of tumor necrosis factor-like weak inducer of apoptosis receptor protein (TWEAKR) expression by Kaposi's sarcoma-associated herpesvirus microRNA prevents TWEAK-induced apoptosis and inflammatory cytokine expression. J Virol 84:12139-12151.
22. Glaunsinger B, Ganem D (2004) Lytic KSHV infection inhibits host gene expression by accelerating global mRNA turnover. Mol Cell 13:713-723. (Pubitemid 38368128)
23. Pfeffer S, et al. (2004) Identification of virus-encoded microRNAs. Science 304: 734-736. (Pubitemid 38560879)
24. Kelly GL, et al. (2009) An Epstein-Barr virus anti-apoptotic protein constitutively expressed in transformed cells and implicated in burkitt lymphomagenesis: The Wp/BHRF1 link. PLoS Pathog 5:e1000341.
25. Nakamura H, et al. (2003) Global changes in Kaposi's sarcoma-associated virus gene expression patterns following expression of a tetracycline-inducible Rta transactivator. J Virol 77:4205-4220. (Pubitemid 36350959)
26. Arias C, Walsh D, Harbell J, Wilson AC, Mohr I (2009) Activation of host translational control pathways by a viral developmental switch. PLoS Pathog 5:e1000334.
27. Bechtel JT, Liang Y, Hvidding J, Ganem D (2003) Host range of Kaposi's sarcoma-associated herpesvirus in cultured cells. J Virol 77:6474-6481. (Pubitemid 36588417)
28. Seo GJ, Fink LH, O'Hara B, Atwood WJ, Sullivan CS (2008) Evolutionarily conserved function of a viral microRNA. J Virol 82:9823-9828.
29. Lin YT, et al. (2010) Small RNA profiling reveals antisense transcription throughout the KSHV genome and novel small RNAs. RNA 16:1540-1558.
30. McClure LV, Lin YT, Sullivan CS (2011) Detection of viral microRNAs by Northern blot analysis. Methods Mol Biol 721:153-171.
31. Sakakibara S, Ueda K, Chen J, Okuno T, Yamanishi K (2001) Octamer-binding sequence is a key element for the autoregulation of Kaposi's sarcoma-associated herpesvirus ORF50/Lyta gene expression. J Virol 75:6894-6900. (Pubitemid 32641576)