K-ras point mutations are rare events in premalignant forms of Barrett's oesophagus

European Journal of Gastroenterology and Hepatology

Volumn 8, Issue 8, 1996, Pages 799-804

  Trautmann, Birgit ^a   Wittekind, Christian ^a   Strobel, Deike ^a   Meixner, Holger ^a   Keymling, Johannes ^a   Gossner, Liebwin ^a   Ell, Christian ^a   Hahn, Eckhart G ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Barrett's oesophagus; Dysplasia; Genes; Metaplasia; Point mutation; Polymerase chain reaction; ras; Restriction fragment length analysis

Indexed keywords

ADENOCARCINOMA; ADULT; AGED; ARTICLE; BARRETT ESOPHAGUS; CANCER RISK; CLINICAL ARTICLE; CODON; CONTROLLED STUDY; DIAGNOSTIC VALUE; ESOPHAGUS BIOPSY; ESOPHAGUS CARCINOMA; FEMALE; HISTOLOGY; HUMAN; MALE; METAPLASIA; ONCOGENE K RAS; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SQUAMOUS EPITHELIUM;

ADENOCARCINOMA; BARRETT ESOPHAGUS; BIOPSY; DISEASE PROGRESSION; ESOPHAGEAL NEOPLASMS; ESOPHAGUS; GENES, RAS; HUMANS; METAPLASIA; POINT MUTATION; POLYMERASE CHAIN REACTION; PRECANCEROUS CONDITIONS;

EID: 0029792591     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Spechler SJ, Goyal RK: Barrett's esophagus. N Engl J Med 1986, 315:362-371.
2. Sjogren RW, Johnson LF: Barrett's esophagus: a review. Am J Med 1983, 74:313-321.
3. Cameron AJ: Barrett's esophagus and adenocarcinoma: from the family to the gene. Gastroenterology 1992, 102(4):1421-1424.
4. Falk GW, Richter JE: Reflux disease and Barrett's esophagus. Endoscopy 1996, 28:13-21.
5. Kahrilas PJ, Hogan WJ: Gastroesophageal reflux disease. In Gastrointestinal Disease: Pathophysiology, Diagnosis, Management. Edited by Sleisenger MH, Fordtran JS. Philadelphia: Saunders; 1993:395-396.
6. Reid BJ, Weinstein WM, Lewin KJ, Haggitt RC, van Deventer G, den Besten L, et al.: Endoscopic biopsy can detect high-grade dysplasia or early adenocarcinoma in Barrett's esophagus without grossly recognizable neoplastic lesions. Gastroenterology 1988, 94(1):81-90.
7. Suarez HG: Activated oncogenes in human tumors. Anticancer Res 1989, 9:1331-1344.
8. Wynford-Thomas D: Oncogenes and anti-oncogenes; the molecular basis of tumour behaviour. J Pathol 1991, 165:187-201.
9. Levine AJ: Tumor suppressor genes. Bioessays 1990, 12(2):60-66.
10. Vogelstein B, Fearon ER, Kern SE, Hamilton SR, Preisinger AC, Nakamura Y, et al.: Allelotype of colorectal carcinomas. Science 1989, 244:207-211.
11. Motojima K, Urano T, Nagata Y, Shiku H, Tsurifune T, Kanematsu T: Detection of point mutations in the Kirsten-ras oncogene provides evidence for multicentricity of pancreatic carcinoma. Ann Surg 1993, 217(2):138-143.
12. Almoguera C, Shibata D, Forrester K, Martin J, Arnheim N, Perucho M: Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. Cell 1988, 53:549-554.
13. Lemoine N: Ras oncogenes in human cancers. In Molecular Biology of Cancer Genes. Edited by Sluyser M. New York: Ellis Horwood; 1990:82-118.
14. Scarpa A, Capelli P, Zamboni G, Bassi C, Hirohashi S: Geographical differences of Ki-ras mutations in European pancreatic carcinomas [abstract]. Digestion 1992, 52:117.
15. Vogelstein B, Fearon ER, Hamilton SR, Kern SE, Preisinger AC, Leppert M, et al.: Genetic alterations during colorectal-tumor development. N Engl J Med 1988, 319:525-532.
16. Forrester K, Almoguera C, Han K, Grizzle WE, Perucho M: Detection of high incidence of K-ras oncogenes during human colon tumorigenesis. Nature 1987, 327:298-303.
17. Bos JL, Fearon ER, Hamilton SR, Verlaan-de Vries M, van Boom JH, van der Eb AJ, et al.: Prevalence of ras gene mutations in human colorectal cancers. Nature 1987, 327:293-297.
18. Bell SM, Scott N, Cross D, Sagar P, Lewis FA, Blair GE, et al.: Prognostic value of p53 overexpression and c-Ki-ras gene mutations in colorectal cancer. Gastroenterology 1993, 104(1):57-64.
19. Shiga C, Shiga K, Sasano H, Mori S: A point mutation of c-Ki-ras gene was found in human esophageal carcinoma cell lines but not in primary esophageal carcinomas. Biochem Biophys Res Commun 1992, 187(1)515-521.
20. Hollstein MC, Smits AM, Galiana C, Yamasaki H, Bos JL, Mandard A, et al.: Amplification of epidermal growth factor receptor gene but no evidence of ras mutations in primary human esophageal cancers. Cancer Res 1988, 48:5119-5123.
21. Jiang W, Kahn SM, Guillem JG, Lu S-H, Weinstein IB: Rapid detection of ras oncogenes in human tumors: applications to colon, esophageal, and gastric cancer. Oncogene 1989, 4(7):923-928.
22. Kahn SM, Jiang W, Weinstein IB: Rapid nonradioactive detection of ras oncogenes in human tumors. Amplifications 1990, 4:22-26.
23. Ritchie AJ, Johnston C, McGuigan J, Gibbons JRP: Differential oncogene expression in the development of Barrett's neoplasia. Gastroenterology 1993, 104(4):178.(Abstract)
24. Jankowski J, Coghill G, Hopwood D, Wormsley KG: Oncogenes and onco-suppressor gene in adenocarcinoma of the oesophagus. Gut 1992, 33:1033-1038.
25. Abdelatif OMA, Chandler FW, Mills LR, McGuire BS, Pantazis CG, Barrett JM: Differential expression of c-myc and H-ras oncogenes in Barrett's epithelium. Arch Pathol Lab Med 1991, 175:880-885.
26. Porschen R, Molsberger G, Sarbia M, Borchard F: Ki-ras and p53 mutations detected by PCR-SSCP analysis in Barrett's associated carcinomas. Gastroenterology 1994, 106:A429.(Abstract)
27. Levine DS, Reid BJ: Endoscopic biopsy technique for acquiring larger mucosal samples. Gastrointest Endosc 1991, 37(3):332-337.
28. Lewin KJ, Riddell RH, Weinstein WM: Barrett's esophagus. In Gastrointestinal Pathology and its Clinical Implications. Edited by Lewin KJ, Riddell RH, Weinstein WM. New York: Jgaku-Shoin; 1992:413-425.
29. Zwas F, Shields HM, Doos WG, Antonioli DA, Goldman H, Ransil BJ, et al.: Scanning electron microscopy of Barrett's epithelium and its correlation with light microscopy and mucin stains. Gastroenterology 1986, 90:1932-1941.
30. Schmidt HG, Riddell RH, Walther B, Skinner DB, Riemann JF: Dysplasia in Barrett's esophagus. J Cancer Res Clin Oncol 1985, 110:145-152.
31. Trautmann B, Schlitt H-J, Hahn EG, Löhr M: Isolation, culture, and characterization of human pancreatic duct cells. Pancreas 1993, 8(2):248-254.
32. Kalthoff H, Schmiegel W, Roeder C, Kasche D, Schmidt A, Lauer G, et al.: p53 and K-ras alterations in pancreatic epithelial cell lesions. Oncogene 1993, 8(2):289-298.
33. Shirasawa S, Furuse M, Yokoyama N, Sasazuki T: Altered growth of human colon cancer cell lines disrupted at activated Ki-ras. Science 1993, 260:85-88.
34. Chen S, Evans GA: Use of polymerase chain reaction for screening transgenic mice. In PCR Protocols: Current Methods and Applications. Edited by White BA. Totowa, NJ: Humana Press Inc.; 1993:75-80.
35. Davis LG, Dibner MD, Battey JF: DNA/RNA extraction and precipitation. In Basic Methods in Molecular Biology. Edited by Davis LG, Dibner MD, Battey JF. New York: Elsevier; 1986:320-323.
36. Haliassos A, Chomel JC, Tesson L, Baudis M, Kruh J, Kaplan JC, et al.: Modification of enzymatically amplified DNA for the detection of point mutations. Nucleic Acids Res 1989, 17(9):3606.
37. Hall A: The cellular functions of small GTP-binding proteins. Science 1990, 249:635-640.
38. Lacal JC, Tronick SR: The ras-oncogene. In The Oncogene Handbook. Edited by Reddy EP, Skalka AM, Curran T. Amsterdam: Elsevier; 1988:257-304.
39. Gasparini P, Bonizzato A., Dognini M, Pignatti PF: Restriction site generating-polymerase chain reaction (RG-PCR) for the probeless detection of hidden genetic variation: application to the study of some common cystic fibrosis mutations. Mol Cell Probes 1992, 6:1-7.
40. van Mansfeld ADM, Bos JL: PCR-based approaches for detection of mutated ras genes. PCR Meth Appl 1992, 1(4):211-216.