Biotransformations with oxidases and peroxidases for the synthesis of optically active building blocks

International Congress Series

Volumn 1233, Issue C, 2002, Pages 45-49

  Lazarus, Michael ^a   Adam, Waldemar ^a   Saha Möller, Chantu R ^a   Schreier, Peter ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

2 Hydroxy acids; Glycolate oxidase; Horseradish peroxidase; Hydroperoxides; Oxidase

Indexed keywords

EID: 79960580530     PISSN: 05315131     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0531-5131(02)00302-3     Document Type: Article

References (11)

1. Adam, W., Lazarus, M., Saha-Möller, C.R., Schreier, P., Biocatalytic synthesis of optically active α-oxyfunctionalized carbonyl compounds. Acc. Chem. Res. 32 (1999), 837-845.
2. Adam, W., Lazarus, M., Saha-Möller, C.R., Weichold, O., Hoch, U., Häring, D., Schreier, P., Biotransformations with peroxidases. Faber, K., (eds.) Advances in Biochemical Engineering/Biotechnology, vol. 63, 1999, Springer-Verlag, Berlin, 73-108.
3. Adam, W., Boland, W., Hartmann-Schreier, J., Humpf, H.-U., Lazarus, M., Saffert, A., Saha-Möller, C.R., Schreier, P., α-Hydroxylation of carboxylic acids with molecular oxygen catalyzed by the α-oxidase of peas (Pisum sativum): a novel biocatalytic synthesis of enantiomerically pure (R)-2-hydroxy acids. J. Am. Chem. Soc. 120 (1998), 11044-11048.
4. Adam, W., Lazarus, M., Boss, B., Humpf, H.-U., Saha-Möller, C.R., Schreier, P., Enzymatic resolution of chiral 2-hydroxy carboxylic acids by the enantioselective oxidation with molecular oxygen catalyzed by the glycolate oxidase from spinach (Spinacia oleracea). J. Org. Chem. 62 (1997), 7841-7843.
5. Adam, W., Hoch, U., Lazarus, M., Saha-Möller, C.R., Schreier, P., Enzyme-catalyzed asymmetric synthesis: kinetic resolution of racemic hydroperoxides by enantioselective reduction to alcohols with horseradish peroxidase. J. Am. Chem. Soc. 117 (1995), 11898-11901.
6. Adam, W., Lazarus, M., Hoch, U., Korb, M.N., Saha-Möller, C.R., Schreier, P., Horseradish-peroxidase-catalyzed enantioselective reduction of racemic hydroperoxy homoallylic alcohols: a novel enzymatic method for the preparation of optically active, unsaturated diols and hydroperoxy alcohols. J. Org. Chem. 63 (1998), 6123-6127.
7. Saffert, A., Hartmann-Schreier, J., Schön, A., Schreier, P., A dual-function alpha-dioxygenase-peroxidase and NAD(+) oxidoreductase active enzyme from germinating pea rationalizing alpha-oxidation of fatty acids in plants. Plant Physiol. 123 (2000), 1545-1552.
8. Adam, W., Korb, M.N., Saha-Möller, C.R., Optically active epoxy diols by titanium-catalyzed oxidation of enantiomerically enriched hydroperoxy and hydroxy homoallylic alcohols. Eur. J. Org. Chem., 1998, 907-912.
9. Adam, W., Korb, M.N., The titanium-catalyzed, asymmetric epoxidation of allylic alcohols with optically active hydroperoxides in the presence of achiral diol ligands. Tetrahedron: Asymmetry 8 (1997), 1131-1142.
10. Adam, W., Bheema Rao, P., Degen, H.-G., Saha-Möller, C.R., Metal-template effect in the asymmetric Weitz–Scheffer epoxidation of α,β-enones by an optically active hydroperoxide. J. Am. Chem. Soc. 122 (2000), 5654-5655.
11. Adam, W., Saha-Möller, C.R., Schmid, K.S., Synthesis of 4,6-dideoxyfuranoses through the regioselective and diastereoselective oxyfunctionalization of a dimethylphenylsilyl-substituted chiral homoallylic alcohol. J. Org. Chem. 66 (2001), 7365-7371.