Lubricant susceptibility of Cellactose and Avicel PH-200: A quantitative relationship

Drug Development and Industrial Pharmacy

Volumn 26, Issue 3, 2000, Pages 297-305

  Flores, Luis Estrada ^a,b   Arellano, Raquel López ^a   Esquivel, Juan José Díaz ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b Sanofi Synthelabo Inc   (United Kingdom)

Author keywords

Cellactose; Lubricant susceptibility; Metamizol sodium; Microcrystalline cellulose

Indexed keywords

AEROSIL; CROSCARMELLOSE SODIUM; DIPYRONE; EXCIPIENT; LACTOSE; LUBRICATING AGENT; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; SILICON DIOXIDE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; FACTORIAL ANALYSIS; LUBRICATION; MULTIPLE REGRESSION; TABLET COMPRESSION; TABLET FORMULATION;

EID: 0034065480     PISSN: 03639045     EISSN: None     Source Type: Journal    
DOI: 10.1081/DDC-100100357     Document Type: Article

References (6)

1. P. Zanowiak, Lubrication in solid dosage form design and manufacture, in Encyclopedia of Pharmaceutical Technology, Vol. 9 (J. Swarbrick and J. C. Boylan, Eds.), p. 87.
2. K. Marshall, Powder properties and test methods, conference presented in the course Granulation, Tabletting and Capsule Technology, Center for Professional Advancement, East Brunswick, NJ, March 18-21, 1996.
3. L. Estrada Flores, R. López Arellano, and J. J. Díaz Esquivel, Study about load capacity of Avicel PH 200 and Cellactose, two direct compression excipients, using experimental design, submitted.
4. J. T. Carstensen, Pharmaceutics of Solids and Solid Dosage Forms, John Wiley and Sons, New York, 1977, pp. 116-118.
5. G. A. Amidon, Physical and mechanical property characterization of powders, in Physical Characterization of Pharmaceutical Solids (H. G. Brittain, Ed.), Marcel Dekker, New York, 1995, pp. 293-294.
6. American Pharmaceutical Association and Pharmaceutical Society of Great Britain, Handbook of Pharmaceutical Excipients, 1st ed. (J. C. Boylan and R. F. Weir, Eds.), Author, 1986, Laboratory Method COM-2, p. 361.