Development of cocaine-induced interstitial lung damage in two CYP2C and VKORC1 variant allele carriers

Molecular Diagnosis and Therapy

Volumn 15, Issue 3, 2011, Pages 177-180

  Wijnen, Petal A H M ^a,b   Bekers, Otto ^a,b   Drent, Marjolein ^a,b  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Interstitial Lung Disease (Ild) Care Consultancy   (Netherlands)

Author keywords

Adverse drug reactions; Cocaine abuse; Genetic polymorphism; Interstitial lung diseases; Pharmacogenetics.

Indexed keywords

ACETYLSALICYLIC ACID; C REACTIVE PROTEIN; COCAINE; CORTICOSTEROID; CYTOCHROME P450 2C; CYTOCHROME P450 2C19; METHADONE; OXIDOREDUCTASE; UNCLASSIFIED DRUG; VITAMIN K EPOXIDE REDUCTASE COMPLEX 1;

ADULT; ALLELE; ANTICOAGULANT THERAPY; ARTICLE; BLOOD CLOTTING; CASE REPORT; COCAINE DEPENDENCE; CORTICOSTEROID THERAPY; COUGHING; DRUG DOSE REDUCTION; FEMALE; FLU LIKE SYNDROME; GENOTYPE; HEART FAILURE; HEART INFARCTION; HETEROZYGOSITY; HUMAN; HYPOXEMIA; INTERSTITIAL LUNG DISEASE; LEUKOCYTE COUNT; LUNG INFILTRATE; LUNG LAVAGE; MALE; METHADONE TREATMENT; MYALGIA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SINGLE NUCLEOTIDE POLYMORPHISM; TACHYPNEA; THORAX RADIOGRAPHY;

ADULT; COCAINE; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; LUNG DISEASES, INTERSTITIAL; MALE; MIXED FUNCTION OXYGENASES; YOUNG ADULT;

EID: 79960575029     PISSN: 11771062     EISSN: 11792000     Source Type: Journal    
DOI: 10.2165/11591080-000000000-00000     Document Type: Article

References (22)

1. Restrepo CS, Carrillo JA, Martinez S, et al. Pulmonary complications from cocaine and cocaine-based substances: imaging manifestations. Radiographics 2007 Jul-Aug; 27 (4): 941-56
2. Tashkin DP. Airway effects of marijuana, cocaine, and other inhaled illicit agents. Curr Opin Pulm Med 2001 Mar; 7 (2): 43-61 (Pubitemid 32260647)
3. Gotway MB, Marder SR, Hanks DK, et al. Thoracic complications of illicit drug use: an organ system approach. Radiographics 2002 Oct; 22 Spec. No.: S119-35
4. Wijnen PA, Drent M, Nelemans PJ, et al. Role of cytochrome P450 polymorphisms in the development of pulmonary drug toxicity: a case-control study in the Netherlands. Drug Saf 2008; 31 (12): 1125-34
5. Ding X, Kaminsky LS. Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts. Annu Rev Pharmacol Toxicol 2003; 43: 149-73 (Pubitemid 37372638)
6. Nishimura M, Yaguti H, Yoshitsugu H, et al. Tissue distribution of mRNA expression of human cytochrome P450 isoforms assessed by high-sensitivity realtime reverse transcription PCR. Yakugaku Zasshi 2003 May; 123 (5): 369-75 (Pubitemid 41327466)
7. Sarikaya D, Bilgen C, Kamataki T, et al. Comparative cytochrome P450 -1A1, -2A6, -2B6, -2C, -2D6, -2E1, -3A5 and -4B1 expressions in human larynx tissue analysed at mRNA level. Biopharm Drug Dispos 2006 Nov; 27 (8): 353-9 (Pubitemid 44842297)
8. Carlson GP. Critical appraisal of the expression of cytochrome P450 enzymes in human lung and evaluation of the possibility that such expression provides evidence of potential styrene tumorigenicity in humans. Toxicology 2008 Dec 5; 254 (1-2): 1-10
9. Pasanen M, Pellinen P, Stenback F, et al. The role of CYP enzymes in cocaineinduced liver damage. Arch Toxicol 1995; 69 (5): 287-90
10. Wijnen PA, Linssen CF, Haenen GR, et al. Variant VKORC1 and CYP2C9 alleles in patients with diffuse alveolar hemorrhage caused by oral anticoagulants. Mol Diagn Ther 2010 Feb 1; 14 (1): 23-30
11. Wijnen PA, Drent M, van Dieijen-Visser MP, et al. Pharmacogenetic testing after a simple DNA isolation method on buccal swab samples. Pharmacogenomics 2009 Jun; 10 (6): 983-7
12. Camus P, Fanton A, Bonniaud P, et al. Interstitial lung disease induced by drugs and radiation. Respiration 2004 Jul-Aug; 71 (4): 301-26 (Pubitemid 39179164)
13. Wijnen PA, Limantoro I, DrentM, et al. Depressive effect of an antidepressant: therapeutic failure of venlafaxine in a case lacking CYP2D6 activity. Ann Clin Biochem 2009 Nov; 46 (Pt 6): 527-30
14. Wijnen PA, Bekers O, DrentM.Relationship between drug-induced interstitial lung diseases and cytochrome P450 polymorphisms. Curr Opin Pulm Med 2010 Sep; 16 (5): 496-502
15. Ben-Zaken Cohen S, Pare PD, Man SF, et al. The growing burden of chronic obstructive pulmonary disease and lung cancer in women: examining sex differences in cigarette smoke metabolism. Am J Respir Crit Care Med 2007 Jul 15; 176 (2): 113-20 (Pubitemid 47057846)
16. Nebert DW, Russell DW.Clinical importance of the cytochromes P450. Lancet 2002 Oct 12; 360 (9340): 1155-62 (Pubitemid 35246494)
17. Bland TM, Haining RL, Tracy TS, et al. CYP2C-catalyzed delta9-tetrahydrocannabinol metabolism: kinetics, pharmacogenetics and interaction with phenytoin. Biochem Pharmacol 2005 Oct 1; 70 (7): 1096-103 (Pubitemid 41262085)
18. Tashkin DP, Khalsa ME, Gorelick D, et al. Pulmonary status of habitual cocaine smokers. Am Rev Respir Dis 1992 Jan; 145 (1): 92-100
19. Waien SA, Hayes Jr D, Leonardo JM. Severe coagulopathy as a consequence of smoking crack cocaine laced with rodenticide. N Engl J Med 2001 Aug 30; 345 (9): 700-1
20. Spahr JE, Maul JS, Rodgers GM. Superwarfarin poisoning: a report of two cases and review of the literature. Am J Hematol 2007 Jul; 82 (7): 656-60 (Pubitemid 47015293)
21. Sconce E, Avery P, Wynne H, et al. Vitamin K supplementation can improve stability of anticoagulation for patients with unexplained variability in response to warfarin. Blood 2007 Mar 15; 109 (6): 2419-23 (Pubitemid 46425883)
22. Sconce EA, Avery PJ, Wynne HA, et al. Vitamin K epoxide reductase complex subunit 1 (VKORC1) polymorphism influences the anticoagulation response subsequent to vitamin K intake: a pilot study. J Thromb Haemost 2008 Jul; 6 (7): 1226-8 (Pubitemid 351859133)