Stability of cognitive functions under mitoxantrone therapy in patients with progressive multiple sclerosis: A pilot analysis

Clinical Neurology and Neurosurgery

Volumn 113, Issue 7, 2011, Pages 527-530

  Schröder, Alexandra ^a   Klotz, Peter ^a   Lee, De Hyung ^a,b   Gold, Ralf ^a   Linker, Ralf A ^a  

^a ST JOSEF HOSPITAL   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Cognitive function; Mitoxantrone; Neuropsychological evaluation; Progressive multiple sclerosis

Indexed keywords

MITOXANTRONE;

ARTICLE; ATTENTION; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; DEPRESSION; FOLLOW UP; HUMAN; MULTIPLE CYCLE TREATMENT; MULTIPLE SCLEROSIS; NEUROLOGIC EXAMINATION; NEUROPSYCHOLOGICAL TEST; VERBAL MEMORY;

ADULT; COGNITION; DEPRESSION; EXECUTIVE FUNCTION; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTELLIGENCE TESTS; MALE; MEMORY; MIDDLE AGED; MITOXANTRONE; MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE; NEUROPSYCHOLOGICAL TESTS; RETROSPECTIVE STUDIES; VERBAL LEARNING;

EID: 79960565373     PISSN: 03038467     EISSN: 18726968     Source Type: Journal    
DOI: 10.1016/j.clineuro.2011.02.018     Document Type: Article

References (39)

1. B. Bagert, P. Camplair, and D. Bourdette Cognitive dysfunction in multiple sclerosis: natural history, pathophysiology and management CNS Drugs 16 7 2002 445 455 (Pubitemid 34729149)
2. M.P. Amato, V. Zipoli, B. Goretti, E. Portaccio, M.F. De Caro, and L. Ricchiuti Benign multiple sclerosis: cognitive, psychological and social aspects in a clinical cohort J Neurol 253 August (8) 2006 1054 1059 (Pubitemid 44441131)
3. O. Ghaffar, and A. Feinstein The neuropsychiatry of multiple sclerosis: a review of recent developments Rev Curr Opin Psychiatry 20 3 2007 278 285 (Pubitemid 46588302)
4. C. Heesen, K.H. Schulz, J. Fiehler, U. Von der Mark, C. Otte, and R. Jung Correlates of cognitive dysfunction in multiple sclerosis Brain Behav Immun May 2010
5. J.M. Rogers, and P.K. Panegyres Cognitive impairment in multiple sclerosis: evidence-based analysis and recommendations J Clin Neurosci 14 10 2007 919 927 (Pubitemid 47333187)
6. J.J. Gonzalez-Rosa, M. Vazquez-Marrufo, E. Vaquero, P. Duque, M. Borges, and M.A. Gamero Differential cognitive impairment for diverse forms of multiple sclerosis BMC Neurosci 7 2006 39
7. S.C. Huijbregts, N.F. Kalkers, L.M. de Sonneville, V. de Groot, I.E. Reuling, and Polman CH Differences in cognitive impairment of relapsing remitting, secondary, and primary progressive MS Neurology 63 2 2004 335 339 (Pubitemid 38971136)
8. C.G. Haase, M. Tinnefeld, and P.M. Faustmann The influence of immunomodulation on psycho-neuroimmunological functions in benign multiple sclerosis Neuroimmunomodulation 11 6 2004 365 372 (Pubitemid 39370444)
9. M.P. Amato, G. Ponziani, G. Pracucci, L. Bracco, G. Siracusa, and L. Amaducci Cognitive impairment in early-onset multiple sclerosis Pattern, predictors, and impact on everyday life in a 4-year follow-up Arch Neurol 52 2 1995 168 172
10. L. Feuillet, F. Reuter, B. Audoin, I. Malikova, K. Barrau, and A.A. Cherif Early cognitive impairment in patients with clinically isolated syndrome suggestive of multiple sclerosis Mult Scler 13 1 2007 124 127 (Pubitemid 46152771)
11. B.I. Glanz, C.M. Holland, S.A. Gauthier, E.L. Amunwa, Z. Liptak, and M.K. Houtchens Cognitive dysfunction in patients with clinically isolated syndromes or newly diagnosed multiple sclerosis Mult Scler 13 8 2007 1004 1010 (Pubitemid 351541435)
12. S.M. Rao, G.J. Leo, L. Bernardin, and F. Unverzagt Cognitive dysfunction in multiple sclerosis I. Frequency, patterns, and prediction Neurology 41 5 1991 685 691
13. S.G. Lynch, B.A. Parmenter, and D.R. Denney The association between cognitive impairment and physical disability in multiple sclerosis Mult Scler 11 August (4) 2005 469 476 (Pubitemid 40984244)
14. A. Achiron, M. Polliack, S.M. Rao, Y. Barak, M. Lavie, and N. Appelboim Cognitive patterns and progression in multiple sclerosis: construction and validation of percentile curves J Neurol Neurosurg Psychiatry 76 5 2005 744 749 (Pubitemid 40569694)
15. M.P. Amato, G. Ponziani, G. Siracusa, and S. Sorbi Cognitive dysfunction in early-onset multiple sclerosis: a reappraisal after 10 years Arch Neurol 58 10 2001 1602 1606 (Pubitemid 32963224)
16. J.A. Bobholz, and S.M. Rao Cognitive dysfunction in multiple sclerosis: a review of recent developments Rev Curr Opin Neurol 16 3 2003 283 288 (Pubitemid 36688294)
17. N.D. Chiaravalloti, and J. DeLuca Cognitive impairment in multiple sclerosis Lancet Neurol 7 12 2008 1139 1151
18. H.M. Genova, J.F. Sumowski, N. Chiaravalloti, G.T. Voelbel, and J. Deluca Cognition in multiple sclerosis: a review of neuropsychological and fMRI research Front Biosci 14 2009 1730 1744
19. S.H. Pierson, and N. Griffith Treatment of cognitive impairment in multiple sclerosis Behav Neurol 17 1 2006 53 67 (Pubitemid 43724319)
20. Schwid SR, Goodman AD, Weinstein A, McDermott MP, Johnson KP; for the Copaxone Study Group. Cognitive function in relapsing multiple sclerosis: minimal changes in a 10-year clinical trial. J Neurol Sci 2007; 255(1-2): 57-63. (Pubitemid 46414020)
21. F. Patti, M.P. Amato, M. Trojano, S. Bastianello, M.R. Tola, and B. Goretti Cognitive impairment and its relation with disease measures in mildly disabled patients with relapsing-remitting multiple sclerosis: baseline results from the Cognitive Impairment in Multiple Sclerosis (COGIMUS) study Mult Scler 15 7 2009 779 788
22. X. Montalban, and J. Rio Interferons and cognition J Neurol Sci 24 1-2 2006 137 140 (Pubitemid 43775932)
23. A. Chan, F.X. Weilbach, K.V. Toyka, and R. Gold Mitoxantrone induces cell death in peripheral blood leucocytes of multiple sclerosis patients Clin Exp Immunol 139 January (1) 2005 152 158 (Pubitemid 40066141)
24. H.P. Hartung, R. Gonsette, N. König, H. Kwiecinski, A. Guseo, S.P. Morrissey Mitoxantrone in Multiple Sclerosis Study Group (MIMS) Mitoxantrone in progressive multiple sclerosis: a placebo-controlled, double-blind, randomised, multicentre trial Lancet 360 9350 2002 2018 2025 (Pubitemid 36026580)
25. O. Neuhaus, B.C. Kieseier, and H.P. Hartung Mitoxantrone (Novantrone) in multiple sclerosis: new insights Expert Rev Neurother 4 1 2004 17 26 (Pubitemid 38082119)
26. R.G. Ghalie, G. Edan, M. Laurent, E. Mauch, S. Eisenman, and H.P. Hartung Cardiac a dverse effects associated with mitoxantrone (Novantrone) therapy in patients with MS Neurology 59 6 2002 909 913
27. H. Zéphir, J. de Sze, K. Dujardin, G. Dubois, M. Cabaret, and S. Bouillaguet Cognitive impact of mitoxantrone and methylprednisolone in multiple sclerosis: an open label study Rev Neurol (Paris) 164 1 2008 47 52 (Pubitemid 351625232)
28. K. Shulman Clock-drawing: is it the ideal cognitive screening test? Int J Geriatr Psychiatry 15 2000 548 561 (Pubitemid 30410000)
29. S. Lehrl Multiple choice vocabulary test (Form B) MWT-B 1989 Perimed Erlangen
30. W. Horn Achievement measure system (Leistungs-Pruef-System/LPS) 1962 Hogrefe Goettingen
31. W. Sturm, and K. Willmes LPS-K - eine LPS-Kurzform für hirngeschädigte Patienten; mit Anleitung zur psychometrischen Einzelfalldiagnostik Diagnostica 29 1983 346 358
32. L.L. Thurstone, and T.G. Thurstone Factorial studies of intelligence. Psychometric monographs 2 1941 Chicago University Press Chicago
33. R. Magliozzi, O. Howell, A. Vora, B. Serafini, R. Nicholas, and M. Puopolo Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology Brain 130 2007 1089 1104 (Pubitemid 47355604)
34. C. Stadelmann, M. Albert, C. Wegner, and W. Brück Cortical pathology in multiple sclerosis Curr Opin Neurol 21 3 2008 229 234 (Pubitemid 351653969)
35. M. Calabrese, F. Agosta, F. Rinaldi, I. Mattisi, P. Grossi, and A. Favaretto Cortical lesions and atrophy associated with cognitive impairment in relapsing-remitting multiple sclerosis Arch Neurol 66 9 2009 1144 1150
36. C. Stadelmann, C. Wegner, and W. Brück Inflammation, demyelination, and degeneration - recent insights from MS pathology Biochim Biophys Acta July 2010
37. C.H. Polman, and R.A. Rudick The multiple sclerosis functional composite: a clinically meaningful measure of disability Neurology 74 April (Suppl. 3) 2010 S8 S15
38. J. Sepulcre, S. Vanotti, R. Hernández, G. Sandoval, F. Cáceres, and O. Garcea Cognitive impairment in patients with multiple sclerosis using the Brief Repeatable Battery-Neuropsychology test Mult Scler 12 2 2006 187 195
39. L.B. Krupp, C. Christodoulou, P. Melville, W.F. Scherl, W.S. MacAllister, and L.E. Elkins Donepezil improved memory in multiple sclerosis in a randomized clinical trial Neurology 63 9 2004 1579 1585 (Pubitemid 39507572)