Determination of raloxifene and its glucuronides in human urine by liquid chromatography-tandem mass spectrometry assay

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 879, Issue 23, 2011, Pages 2323-2331

  Trdan, Tina ^a   Roškar, Robert ^a   Trontelj, Jurij ^a   Ravnikar, Matjaž ^a   Mrhar, Aleš ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

Doping; Glucuronide; LC MS MS; Pharmacokinetics; Raloxifene; Urine

Indexed keywords

ANALYTICAL METHOD; BIOCONVERSION PROCESS; BIOLOGICAL SAMPLES; DETERMINATION COEFFICIENTS; GLUCURONIDES; HUMAN URINE; LC-MS/MS; LIMITS OF QUANTIFICATION; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY ASSAYS; POTENTIAL APPLICATIONS; RALOXIFENE; REAL URINE; SIMULTANEOUS DETERMINATIONS; SOLID-PHASE EXTRACTION; STREPTOMYCES SP; URINE; URINE SAMPLE; VALIDATED METHODS;

BODY FLUIDS; EXTRACTION; LIQUIDS; MASS SPECTROMETRY; PHARMACOKINETICS;

LIQUID CHROMATOGRAPHY;

GLUCURONIDE; RALOXIFENE; RALOXIFENE 4' BETA GLUCURONIDE; RALOXIFENE 6 BETA GLUCURONIDE; RALOXIFENE 6,4' DIGLUCURONIDE; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG METABOLISM; DRUG STABILITY; DRUG STRUCTURE; DRUG URINE LEVEL; FEMALE; HUMAN; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; METABOLITE; NONHUMAN; PRIORITY JOURNAL; SOLID PHASE EXTRACTION; STREPTOMYCES; TANDEM MASS SPECTROMETRY; URINALYSIS;

CHROMATOGRAPHY, LIQUID; GLUCURONIDES; HUMANS; RALOXIFENE; TANDEM MASS SPECTROMETRY;

STREPTOMYCES SP.;

EID: 79960563050     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2011.06.031     Document Type: Article

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