Endogenous and diet-induced hypercholesterolemia in nonhuman primates: Effects of age, adiposity, and diabetes on lipoprotein profiles

Metabolism: Clinical and Experimental

Volumn 60, Issue 8, 2011, Pages 1165-1177

  Shamekh, Rania ^a   Linden, Ellen H ^a   Newcomb, Jennifer D ^a   Tigno, Xenia T ^a   Catherine Jen, Kai Lin ^b   Pellizzon, Michael A ^c   Hansen, Barbara C ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

^c Research Diets Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; LIPOPROTEIN;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; HUMAN VERSUS ANIMAL COMPARISON; HYPERCHOLESTEROLEMIA; LIPID DIET; LIPOPROTEIN BLOOD LEVEL; LOW FAT DIET; MALE; NONHUMAN; OBESITY; PRIORITY JOURNAL; RHESUS MONKEY;

ADIPOSITY; AGING; ANIMALS; BODY WEIGHT; CHOLESTEROL, HDL; CHOLESTEROL, LDL; DIABETES MELLITUS, TYPE 2; DIET; DIETARY FATS; FEMALE; HYPERCHOLESTEROLEMIA; MACACA MULATTA; MALE;

EID: 79960559304     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2010.12.012     Document Type: Article

References (62)

1. Clarkson T.B., and Mehaffey M.H. Coronary heart disease of females: lessons learned from nonhuman primates Am J Primatol 71 2009 785 793
2. Shively C.A., Register T.C., and Clarkson T.B. Social stress, visceral obesity, and coronary artery atherosclerosis in female primates Obesity (Silver Spring) 17 2009 1513 1520
3. Shively C.A., Register T.C., and Clarkson T.B. Social stress, visceral obesity, and coronary artery atherosclerosis: product of a primate adaptation Am J Primatol 71 2009 742 751
4. Ding S.Y., Tigno X.T., and Hansen B.C. Nuclear magnetic resonance-determined lipoprotein abnormalities in nonhuman primates with the metabolic syndrome and type 2 diabetes mellitus Metabolism 56 2007 838 846 (Pubitemid 46738570)
5. Hannah J.S., Verdery R.B., Bodkin N.L., Hansen B.C., Le N.A., and Howard B.V. Changes in lipoprotein concentrations during the development of noninsulin-dependent diabetes mellitus in obese rhesus monkeys (Macaca mulatta) J Clin Endocrinol Metab 72 1991 1067 1072 (Pubitemid 21921808)
6. Kavanagh K., Fairbanks L.A., Bailey J.N., Jorgensen M.J., Wilson M., and Zhang L. Characterization and heritability of obesity and associated risk factors in vervet monkeys Obesity (Silver Spring) 15 2007 1666 1674 (Pubitemid 47264945)
7. Tigno X.T., Gerzanich G., and Hansen B.C. Age-related changes in metabolic parameters of nonhuman primates J Gerontol A Biol Sci Med Sci 59 2004 1081 1088 (Pubitemid 40024272)
8. Baker H.N., Eggen D.A., Melchior G.W., Roheim P.S., Malcom G.T., and Strong J.P. Lipoprotein profiles in rhesus monkeys with divergent responses to dietary cholesterol Arteriosclerosis 3 1983 223 232 (Pubitemid 13099584)
9. Ershow A.G., Nicolosi R.J., and Hayes K.C. Separation of the dietary fat and cholesterol influences on plasma lipoproteins of rhesus monkeys Am J Clin Nutr 34 1981 830 840 (Pubitemid 11077915)
10. Pronczuk A., Patton G.M., Stephan Z.F., and Hayes K.C. Species variation in the atherogenic profile of monkeys: relationship between dietary fats, lipoproteins, and platelet aggregation Lipids 26 1991 213 222
11. Rudel L.L., Kelley K., Sawyer J.K., Shah R., and Wilson M.D. Dietary monounsaturated fatty acids promote aortic atherosclerosis in LDL receptor-null, human ApoB100-overexpressing transgenic mice Arterioscler Thromb Vasc Biol 18 1998 1818 1827 (Pubitemid 28521074)
12. Rudel L.L., Parks J.S., and Sawyer J.K. Compared with dietary monounsaturated and saturated fat, polyunsaturated fat protects African green monkeys from coronary artery atherosclerosis Arterioscler Thromb Vasc Biol 15 1995 2101 2110 (Pubitemid 26001412)
13. Hachem S.B., and Mooradian A.D. Familial dyslipidaemias: an overview of genetics, pathophysiology and management Drugs 66 2006 1949 1969 (Pubitemid 44771933)
14. Neven L., Khalil A., Pfaffinger D., Fless G.M., Jackson E., and Scanu A.M. Rhesus monkey model of familial hypercholesterolemia: relation between plasma Lp[a] levels, apo[a] isoforms, and LDL-receptor function J Lipid Res 31 1990 633 643 (Pubitemid 20167630)
15. Scanu A.M., Khalil A., Neven L., Tidore M., Dawson G., and Pfaffinger D. Genetically determined hypercholesterolemia in a rhesus monkey family due to a deficiency of the LDL receptor J Lipid Res 29 1988 1671 1681 (Pubitemid 19030536)
16. Institute of Laboratory Animal Resources (U.S.), and Committee on Care and Use of Laboratory Animals Guide for the care and use of laboratory animals 1996 U.S. Dept. of Health and Human Services, Public Health Service Bethesda (Md) [NIH publication]
17. Lab Diet. Non-human primate diets: PDF 5037-5038 Lab Diet PMI Nutrition International. http://www.labdiet.com/primate-diet.html.
18. Jen K.L., and Hansen B.C. Glucose disappearance rate in rhesus monkeys: some technical considerations Am J Primatol 14 1988 3 166
19. Buettner R., Scholmerich J., and Bollheimer L.C. High-fat diets: modeling the metabolic disorders of human obesity in rodents Obesity (Silver Spring) 15 2007 798 808 (Pubitemid 46740952)
20. Surwit R.S., Feinglos M.N., Rodin J., Sutherland A., Petro A.E., and Opara E.C. Differential effects of fat and sucrose on the development of obesity and diabetes in C57BL/6J and A/J mice Metabolism 44 1995 645 651
21. CDC Cholesterol http://www.cdc.gov/nchs/
22. Feeman W.E. Jr Guidelines for diagnosis and treatment of high cholesterol JAMA 286 2001 2400 [author reply 2401-2402]
23. Pauciullo P., Gentile M., Marotta G., Baiano A., Ubaldi S., and Jossa F. Small dense low-density lipoprotein in familial combined hyperlipidemia: independent of metabolic syndrome and related to history of cardiovascular events Atherosclerosis 203 2009 320 324
24. Association AH Cholesterol [electronic article]. American Heart Association http://www.americanheart.org/presenter.jhtml?identifier=4488
25. Caldwell L.R. Guidelines for diagnosis and treatment of high cholesterol JAMA 286 2001 2400 [author reply 2401-2]
26. Ring B.L. Guidelines for diagnosis and treatment of high cholesterol JAMA 286 2001 2401 2402
27. Rosch P.J. Guidelines for diagnosis and treatment of high cholesterol JAMA 286 2001 2401 [author reply 2401-2]
28. Ding S.Y., Tigno X.T., Braileanu G.T., Ito K., and Hansen B.C. A novel peroxisome proliferator-activated receptor alpha/gamma dual agonist ameliorates dyslipidemia and insulin resistance in prediabetic rhesus monkeys Metabolism 56 2007 1334 1339 (Pubitemid 47422240)
29. Kharitonenkov A., Wroblewski V.J., Koester A., Chen Y.F., Clutinger C.K., and Tigno X.T. The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21 Endocrinology 148 2007 774 781 (Pubitemid 46143178)
30. Oliver W.R. Jr., Shenk J.L., Snaith M.R., Russell C.S., Plunket K.D., and Bodkin N.L. A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport Proc Natl Acad Sci U S A 98 2001 5306 5311 (Pubitemid 32397124)
31. Smucny D.A., Allison D.B., Ingram D.K., Roth G.S., Kemnitz J.W., Kohama S.G., Lane M.A., and Black A. Changes in blood chemistry and hematology variables during aging in captive rhesus macaques (Macaca mulatta) J Med Primatol 30 2001 161 173 [J Med Primatol 33: 48-54, 2004] (Pubitemid 32725728)
32. Schuurman H.J., and Smith H.T. Reference values for clinical chemistry and clinical hematology parameters in cynomolgus monkeys Xenotransplantation 12 2005 72 75 (Pubitemid 40105151)
33. Walter M. Interrelationships among HDL metabolism, aging, and atherosclerosis Arterioscler Thromb Vasc Biol 29 2009 1244 1250
34. Smucny D.A., Allison D.B., Ingram D.K., Roth G.S., Kemnitz J.W., and Kohama S.G. Changes in blood chemistry and hematology variables during aging in captive rhesus macaques (Macaca mulatta) J Med Primatol 30 2001 161 173 (Pubitemid 32725728)
35. Vierhapper H., Nardi A., and Grosser P. Prevalence of paradoxically normal serum cholesterol in morbidly obese women Metabolism 49 2000 607 610 (Pubitemid 30305258)
36. Schaefer E.J., Lamon-Fava S., Cohn S.D., Schaefer M.M., Ordovas J.M., and Castelli W.P. Effects of age, gender, and menopausal status on plasma low density lipoprotein cholesterol and apolipoprotein B levels in the Framingham Offspring Study J Lipid Res 35 1994 779 792 (Pubitemid 24157230)
37. Ferrara A., Barrett-Connor E., and Shan J. Total, LDL, and HDL cholesterol decrease with age in older men and women. The Rancho Bernardo Study 1984-1994 Circulation 96 1997 37 43 (Pubitemid 27298401)
38. Esteve E., Ricart W., and Fernandez-Real J.M. Dyslipidemia and inflammation: an evolutionary conserved mechanism Clin Nutr 24 2005 16 31
39. Giunta S. Exploring the complex relations between inflammation and aging (inflamm-aging): anti-inflamm-aging remodelling of inflamm-aging, from robustness to frailty Inflamm Res 57 2008 558 563
40. Abbott R.D., Sharp D.S., Burchfiel C.M., Curb J.D., Rodriguez B.L., and Hakim A.A. Cross-sectional and longitudinal changes in total and high-density-lipoprotein cholesterol levels over a 20-year period in elderly men: the Honolulu Heart Program Ann Epidemiol 7 1997 417 424
41. Garg A., and Simha V. Update on dyslipidemia J Clin Endocrinol Metab 92 2007 1581 1589
42. Berneis K.K., and Krauss R.M. Metabolic origins and clinical significance of LDL heterogeneity J Lipid Res 43 2002 1363 1379
43. Rizzo M., and Berneis K. Small, dense low-density-lipoproteins and the metabolic syndrome Diabetes Metab Res Rev 23 2007 14 20 (Pubitemid 46152481)
44. Krauss R.M. Dietary and genetic effects on low-density lipoprotein heterogeneity Annu Rev Nutr 21 2001 283 295 (Pubitemid 32695273)
45. Kwiterovich P.O. Jr Clinical relevance of the biochemical, metabolic, and genetic factors that influence low-density lipoprotein heterogeneity Am J Cardiol 90 2002 30i 47i (Pubitemid 35284909)
46. Krauss R.M., Williams P.T., Lindgren F.T., and Wood P.D. Coordinate changes in levels of human serum low and high density lipoprotein subclasses in healthy men Arteriosclerosis 8 1988 155 162 (Pubitemid 18090923)
47. Yoshino G., Hirano T., and Kazumi T. Treatment of small dense LDL J Atheroscler Thromb 9 2002 266 275
48. Lada A.T., and Rudel L.L. Dietary monounsaturated versus polyunsaturated fatty acids: which is really better for protection from coronary heart disease? Curr Opin Lipidol 14 2003 41 46 (Pubitemid 36183100)
49. Sacks F.M., and Campos H. Clinical review 163: cardiovascular endocrinology: low-density lipoprotein size and cardiovascular disease: a reappraisal J Clin Endocrinol Metab 88 2003 4525 4532 (Pubitemid 37357487)
50. Bodkin N.L., Alexander T.M., Ortmeyer H.K., Johnson E., and Hansen B.C. Mortality and morbidity in laboratory-maintained rhesus monkeys and effects of long-term dietary restriction J Gerontol A Biol Sci Med Sci 58 2003 212 219 (Pubitemid 36307591)
51. Hannah J.S., Yamane K., Kataoka S., Anthony M., and Howard B.V. High fat, high cholesterol diets alter low density lipoprotein size and binding affinity in monkeys Atherosclerosis 132 1997 19 27 (Pubitemid 27306735)
52. Dreon D.M., Fernstrom H.A., Miller B., and Krauss R.M. Low-density lipoprotein subclass patterns and lipoprotein response to a reduced-fat diet in men FASEB J 8 1994 121 126 (Pubitemid 24047420)
53. Krauss R.M., and Dreon D.M. Low-density-lipoprotein subclasses and response to a low-fat diet in healthy men Am J Clin Nutr 62 1995 478S 487S
54. Howard B.V., Manson J.E., Stefanick M.L., Beresford S.A., Frank G., and Jones B. Low-fat dietary pattern and weight change over 7 years: the Women's Health Initiative Dietary Modification Trial JAMA 295 2006 39 49 (Pubitemid 43042688)
55. Sacks F.M., Bray G.A., Carey V.J., Smith S.R., Ryan D.H., and Anton S.D. Comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates N Engl J Med 360 2009 859 873
56. Adams M.R., Golden D.L., Williams J.K., Franke A.A., Register T.C., and Kaplan J.R. Soy protein containing isoflavones reduces the size of atherosclerotic plaques without affecting coronary artery reactivity in adult male monkeys J Nutr 135 2005 2852 2856 (Pubitemid 43156552)
57. Bodkin N.L., and Hansen B.C. Antihypertensive effects of captopril without adverse effects on glucose tolerance in hyperinsulinemic rhesus monkeys J Med Primatol 24 1995 1 6
58. Bodkin N.L., Pill J., Meyer K., and Hansen B.C. The effects of K-111, a new insulin-sensitizer, on metabolic syndrome in obese prediabetic rhesus monkeys Horm Metab Res 35 2003 617 624 (Pubitemid 37445331)
59. Ortmeyer H.K., Bodkin N.L., Haney J., Yoshioka S., Horikoshi H., and Hansen B.C. A thiazolidinedione improves in vivo insulin action on skeletal muscle glycogen synthase in insulin-resistant monkeys Int J Exp Diabetes Res 1 2000 195 202
60. Ortmeyer H.K., Huang L.C., Zhang L., Hansen B.C., and Larner J. Chiroinositol deficiency and insulin resistance. II. Acute effects of d-chiroinositol administration in streptozotocin-diabetic rats, normal rats given a glucose load, and spontaneously insulin-resistant rhesus monkeys Endocrinology 132 1993 646 651 (Pubitemid 23056121)
61. Ortmeyer H.K., Sajan M.P., Miura A., Kanoh Y., Rivas J., and Li Y. Intracellular insulin signaling and insulin sensitizing in muscle and liver of obese monkeys: PPAR gamma agonist improves defective activation of atypical protein kinase C Antioxid Redox Signal 14 2011 207 219
62. Schafer S.A., Hansen B.C., Volkl A., Fahimi H.D., and Pill J. Biochemical and morphological effects of K-111, a peroxisome proliferator-activated receptor (PPAR)alpha activator, in non-human primates Biochemical pharmacology 68 2004 239 251 (Pubitemid 38757693)