A simple HPLC-UV method for the simultaneous quantification of gefitinib and erlotinib in human plasma

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 879, Issue 23, 2011, Pages 2345-2350

  Faivre, Lionel ^a   Gomo, Charline ^a   Mir, Olivier ^a,b   Taieb, Fabrice ^a   Schoemann Thomas, Audrey ^a,b   Ropert, Stanislas ^a,b   Vidal, Michel ^a,b   Dusser, Daniel ^a,b   Dauphin, Alain ^a   Goldwasser, Francois ^a,b   Blanchet, Benoit ^a  

^a ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Cancer patients; Erlotinib; Gefitinib; Liquid chromatography; Therapeutic drug monitoring; UV detection

Indexed keywords

CANCER PATIENTS; ERLOTINIB; GEFITINIB; THERAPEUTIC DRUG MONITORING; UV DETECTION;

AMINO ACIDS; AMMONIUM COMPOUNDS; DISEASES; LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETRY; PATIENT MONITORING; SOLVENT EXTRACTION;

PLASMAS;

ACEPROMAZINE; ACETONITRILE; AJMALINE; AMIODARONE; AMLODIPINE; AMMONIUM ACETATE; BUDESONIDE; CIPROFLOXACIN; CLONAZEPAM; CYCLOSPORIN; DIGOXIN; ENOXAPARIN; ERLOTINIB; ESCITALOPRAM; EVEROLIMUS; FOSFOMYCIN; GEFITINIB; GENTAMICIN; HEPARIN; HYDROCORTISONE; OXYCODONE; PARACETAMOL; PROPRANOLOL; RIFAMPICIN; SORAFENIB; SUNITINIB; TACROLIMUS; TAZOBACTAM; UNINDEXED DRUG; VERAPAMIL;

ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; DRUG RETENTION; DRUG STABILITY; ELUTION; FLOW RATE; FREEZE THAWING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INSTRUMENT VALIDATION; LIMIT OF QUANTITATION; LIQUID LIQUID EXTRACTION; LUNG NON SMALL CELL CANCER; PLASMA; PRIORITY JOURNAL; STEADY STATE; ULTRAVIOLET SPECTROSCOPY;

ANTINEOPLASTIC AGENTS; CARCINOMA, NON-SMALL-CELL LUNG; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; LUNG NEOPLASMS; QUINAZOLINES; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 79960559180     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2011.06.026     Document Type: Article

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