SCOPUS 정보 검색 플랫폼

Volumn 401, Issue 2, 2011, Pages 529-541

Urinary excretion profiles of toremifene metabolites by liquid chromatography-mass spectrometry. Towards targeted analysis to relevant metabolites in doping control

(3) Mazzarino, Monica a De La Torre, Xavier a Botrè, Francesco a,b

a Laboratorio Antidoping (Italy)

b SAPIENZA UNIVERSITY OF ROME (Italy)

Author keywords

Antidoping analysis; LC MS; SERMs; Toremifene

Indexed keywords

ACCURATE MASS; ACQUISITION MODES; ANTIDOPING ANALYSIS; COLLISION-INDUCED DISSOCIATION; DOPING CONTROL; DOPING CONTROL ANALYSIS; DRUG ADMINISTRATION; ELEMENTAL COMPOSITIONS; GLUCURONIDES; HYDROXYLATED METABOLITES; ION SCAN; ISOTOPE PATTERN; LC-MS; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; METABOLIC REACTIONS; NEUTRAL LOSS; ORAL ADMINISTRATION; SELECTED REACTION MONITORING; SERMS; SIDE-CHAINS; SINGLE-DOSE; STRUCTURE ELUCIDATION; SULPHATES; TIME-OF-FLIGHT SYSTEM; TOREMIFENE; URINARY EXCRETION; URINE SAMPLE;

BIOMOLECULES; CARBOXYLATION; CHLORINE; HYDROXYLATION; IONS; ISOTOPES; LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETRY; METABOLITES; MONITORING; ORGANIC POLYMERS; PHYSIOLOGY;

METABOLISM;

PERFORMANCE ENHANCING SUBSTANCE; TOREMIFENE;

ADULT; ARTICLE; CHEMISTRY; DOPING; FEMALE; HUMAN; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; REFERENCE VALUE; SENSITIVITY AND SPECIFICITY; SUBSTANCE ABUSE; URINE;

ADULT; CHROMATOGRAPHY, LIQUID; DOPING IN SPORTS; FEMALE; HUMANS; MASS SPECTROMETRY; PERFORMANCE-ENHANCING SUBSTANCES; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; SUBSTANCE ABUSE DETECTION; TOREMIFENE;

EID: 79960556840 PISSN: 16182642 EISSN: 16182650 Source Type: Journal
DOI: 10.1007/s00216-011-4695-y Document Type: Article

Times cited : (8)

References (29)

1
- 0027463002
- 10.1007/BF00662401
- P Dombernowsky 1993 Breast Cancer Res Treat 25 57 63 10.1007/BF00662401
- (1993) Breast Cancer Res Treat , vol.25 , pp. 57-63
- Dombernowsky, P.¹

2
- 0034091458
- 10.1093/humupd/6.3.212 1:CAS:528:DC%2BD3cXksFequr8%3D
- SR Goldstein S Siddhanti AV Ciaccia L Plouffe 2000 Hum Reprod Update 6 3 212 224 10.1093/humupd/6.3.212 1:CAS:528:DC%2BD3cXksFequr8%3D
- (2000) Hum Reprod Update , vol.6 , Issue.3 , pp. 212-224
- Goldstein, S.R.¹ Siddhanti, S.² Ciaccia, A.V.³ Plouffe, L.⁴

3
- 0025292192
- Review of the pharmacological properties of toremifene
- DOI 10.1016/0022-4731(90)90003-B
- L Kangas 1990 J Steroid Biochem 36 191 195 10.1016/0022-4731(90)90003-B 1:CAS:528:DyaK3cXltVymur8%3D (Pubitemid 20222766)
- (1990) Journal of Steroid Biochemistry , vol.36 , Issue.3 , pp. 191-195
- Kangas, L.¹

4
- 0034076810
- Selective oestrogen receptor modifiers (SERMs) and breast cancer therapy
- DOI 10.1053/ctrv.1999.0162
- EA Lien PE Lønning 2000 Cancer Treat Rev 26 205 227 10.1053/ctrv.1999.0162 1:CAS:528:DC%2BD3cXksFSqt7k%3D (Pubitemid 30330665)
- (2000) Cancer Treatment Reviews , vol.26 , Issue.3 , pp. 205-227
- Lien, E.A.¹ Lonning, P.E.²

5
- 0036299286
- SERMs: Current status and future trends
- DOI 10.1016/S1040-8428(02)00022-7, PII S1040842802000227
- KC Morello GT Wurz MW DeGregorio 2002 Crit Rev Oncol Hematol 43 63 76 10.1016/S1040-8428(02)00022-7 (Pubitemid 34722788)
- (2002) Critical Reviews in Oncology/Hematology , vol.43 , Issue.1 , pp. 63-76
- Morello, K.C.¹ Wurz, G.T.² DeGregorio, M.W.³

6
- 0030924928
- Influence of age on toremifene pharmacokinetics
- DOI 10.1007/s002800050645
- EA Sotaniemi MI Anttila 1997 Cancer Chemother Pharmacol 40 185 188 10.1007/s002800050645 1:CAS:528:DyaK2sXjsFKhtLs%3D (Pubitemid 27214599)
- (1997) Cancer Chemotherapy and Pharmacology , vol.40 , Issue.2 , pp. 185-188
- Sotaniemi, E.A.¹ Anttila, M.I.²

7
- 0028793801
- 10.1006/gyno.1995.0019 1:CAS:528:DyaK28XisFKktA%3D%3D
- E Tomas A Kauppila G Blanco M Apaja-Sarkkinen T Laatikainen 1995 Gynecol Oncol 59 261 266 10.1006/gyno.1995.0019 1:CAS:528:DyaK28XisFKktA%3D%3D
- (1995) Gynecol Oncol , vol.59 , pp. 261-266
- Tomas, E.¹ Kauppila, A.² Blanco, G.³ Apaja-Sarkkinen, M.⁴ Laatikainen, T.⁵

8
- 0023913406
- Toremifene, a new antiestrogenic compound, for treatment of advanced breast cancer. Phase II study
- DOI 10.1016/0277-5379(88)90316-1
- R Valavaara S Pyrhonen M Heikkinen P Rissanen G Blanco E Tholix E Nordman D Taskinen L Holsti A Hajba 1988 Eur J Cancer 24 785 790 10.1016/0277-5379(88) 90316-1 1:STN:280:DyaL1c3lsFSgsg%3D%3D (Pubitemid 18095588)
- (1988) European Journal of Cancer and Clinical Oncology , vol.24 , Issue.4 , pp. 785-790
- Valavaara, R.¹ Pyrhonen, S.² Heikkinen, M.³ Rissanen, P.⁴ Blanco, G.⁵ Tholix, E.⁶ Nordman, E.⁷ Taskinen, P.⁸ Holsti, L.⁹ Hajba, A.¹⁰

9
- 0025136713
- Pharmacokinetics of toremifene and its metabolites in patients with advanced breast cancer
- DOI 10.1007/BF00684880
- VJ Weibe C Benz I Shemano TB Cadman MW DeGregorio 1990 Cancer Chemother Pharmacol 25 247 251 10.1007/BF00684880 (Pubitemid 20014966)
- (1990) Cancer Chemotherapy and Pharmacology , vol.25 , Issue.4 , pp. 247-251
- Wiebe, V.J.¹ Benz, C.C.² Shemano, I.³ Cadman, T.B.⁴ DeGregorio, M.W.⁵

10
- 3342932419
- Pharmacological characterization of 4-hydroxy-N-desmethyl tamoxifen, a novel active metabolite of tamoxifen
- DOI 10.1023/B:BREA.0000025406.31193.e8
- MD Johnson H Zuo K-H Lee JP Trebley JM Rae RV Weatherman Z Desta DA Flockhart TC Skaar 2004 Breast Cancer Res Treat 85 2 151 159 10.1023/B:BREA.0000025406.31193.e8 1:CAS:528:DC%2BD2cXjsVertbc%3D (Pubitemid 38987269)
- (2004) Breast Cancer Research and Treatment , vol.85 , Issue.2 , pp. 151-159
- Johnson, M.D.¹ Zuo, H.² Lee, K.-H.³ Trebley, J.P.⁴ Rae, J.M.⁵ Weatherman, R.V.⁶ Desta, Z.⁷ Flockhart, D.A.⁸ Skaar, T.C.⁹

11
- 34548638977
- New insights into the metabolism of tamoxifen and its role in the treatment and prevention of breast cancer
- DOI 10.1016/j.steroids.2007.07.009, PII S0039128X07001225
- VG Jordan 2007 Steroids 72 829 842 10.1016/j.steroids.2007.07.009 1:CAS:528:DC%2BD2sXhtVOit77L (Pubitemid 47410069)
- (2007) Steroids , vol.72 , Issue.13 , pp. 829-842
- Jordan, V.C.¹

12
- 33646435277
- 10.1210/jc.2005-2569 1:CAS:528:DC%2BD28XkslCntrk%3D Clinical review
- DJ Handelsman 2006 J Clin Endocrinol Metab 91 5 1646 1653 10.1210/jc.2005-2569 1:CAS:528:DC%2BD28XkslCntrk%3D Clinical review
- (2006) J Clin Endocrinol Metab , vol.91 , Issue.5 , pp. 1646-1653
- Handelsman, D.J.¹

13
- 44349153486
- Indirect androgen doping by oestrogen blockade in sports
- DOI 10.1038/bjp.2008.150, PII BJP2008150
- DJ Handelsman 2008 Br J Pharmacol 154 598 605 10.1038/bjp.2008.150 1:CAS:528:DC%2BD1cXmt1Kqtbw%3D (Pubitemid 351744950)
- (2008) British Journal of Pharmacology , vol.154 , Issue.3 , pp. 598-605
- Handelsman, D.J.¹

14
- 3543014876
- The 2011 Prohibited List International Standard. World Anti-Doping Agency, Montreal, Canada. Available at:
- The World Anti-Doping Code. The 2011 Prohibited List International Standard. World Anti-Doping Agency, Montreal, Canada. Available at: www.wada-ama.org
- The World Anti-Doping Code

15
- 0036689529
- Toremifene metabolism in rat, mouse and human liver microsomes: Identification of α-hydroxtoremifene by LC-MS
- DOI 10.1002/bmc.171
- M Russell CK Lim 2002 Biomed Chromatogr 16 361 363 10.1002/bmc.171 (Pubitemid 34982348)
- (2002) Biomedical Chromatography , vol.16 , Issue.5 , pp. 361-363
- Jones, R.M.¹ Lim, C.K.²

16
- 0028174979
- 10.1080/10826079408013457 1:CAS:528:DyaK2cXktVSitrg%3D
- EK Lim Z-X Yuan K-E Ying LL Smith 1994 Liq Chromatogr 17 1773 1783 10.1080/10826079408013457 1:CAS:528:DyaK2cXktVSitrg%3D
- (1994) Liq Chromatogr , vol.17 , pp. 1773-1783
- Lim, E.K.¹ Yuan, Z.-X.² Ying, K.-E.³ Smith, L.L.⁴

17
- 0025793178
- 10.1016/0378-4347(91)80414-8 1:CAS:528:DyaK3MXksVWit7c%3D
- LK Webster NA Crinis KH Stokes JF Bishop 1991 Chromatogr 565 482 487 10.1016/0378-4347(91)80414-8 1:CAS:528:DyaK3MXksVWit7c%3D
- (1991) Chromatogr , vol.565 , pp. 482-487
- Webster, L.K.¹ Crinis, N.A.² Stokes, K.H.³ Bishop, J.F.⁴

18
- 0024832067
- Liquid chromatographic-atmospheric pressure ionization mass spectrometric analysis of toremifene metabolites in human urine
- DOI 10.1016/0378-4347(89)80016-7
- N Watanabe T Irie M Koyama 1989 J Chromatogr 497 169 180 10.1016/0378-4347(89)80016-7 1:CAS:528:DyaK3cXltVylt78%3D (Pubitemid 20027113)
- (1989) Journal of Chromatography - Biomedical Applications , vol.497 , pp. 169-180
- Watanabe, N.¹ Irie, T.² Koyama, M.³ Tominaga, T.⁴

19
- 0033678649
- 10.2165/00003088-200039050-00002
- TL Taras GT Wurz GR Linares MW DeGregorio 2000 Clin Pharmacokinet 5 327 334 10.2165/00003088-200039050-00002
- (2000) Clin Pharmacokinet , vol.5 , pp. 327-334
- Taras, T.L.¹ Wurz, G.T.² Linares, G.R.³ Degregorio, M.W.⁴

20
- 0025365865
- Metabolism of toremifene in the rat
- DOI 10.1016/0022-4731(90)90007-F
- H Sipilä L Kangas L Vuorilehto A Kalapudas M Eloranta M Sördevall R Toivola M Anttila 1990 J Steroid Biochem 36 211 215 10.1016/0022-4731(90)90007-F (Pubitemid 20222770)
- (1990) Journal of Steroid Biochemistry , vol.36 , Issue.3 , pp. 211-215
- Sipila, H.¹ Kangas, L.² Vuorilehto, L.³ Kalapudas, A.⁴ Eloranta, M.⁵ Sodervall, M.⁶ Toivola, R.⁷ Anttila, M.⁸

21
- 0036689529
- Toremifene metabolism in rat, mouse and human liver microsomes: Identification of α-hydroxtoremifene by LC-MS
- DOI 10.1002/bmc.171
- RM Jones CK Lim 2002 Biomed Chomatogr 16 361 363 10.1002/bmc.171 1:CAS:528:DC%2BD38XmvFWht7g%3D (Pubitemid 34982348)
- (2002) Biomedical Chromatography , vol.16 , Issue.5 , pp. 361-363
- Jones, R.M.¹ Lim, C.K.²

22
- 0027195827
- High-performance liquid chromatography analysis of tamoxifen, toremifene and their major human metabolites
- DOI 10.1016/0378-4347(93)80478-M
- F Berthou Y Dréano 1993 Chromatogr 616 117 127 10.1016/0378-4347(93)80478-M 1:CAS:528:DyaK3sXltVygsrc%3D (Pubitemid 23189991)
- (1993) Journal of Chromatography - Biomedical Applications , vol.616 , Issue.1 , pp. 117-127
- Berthou, F.¹ Dreano, Y.²

23
- 0030043055
- Liquid chromatography-thermospray mass spectrometry of toremifene and its derivatives
- DOI 10.1016/0021-9673(95)01126-9
- A Martinsen J Gynther 1996 J Chromatogr A 724 358 363 10.1016/0021-9673(95)01126-9 1:CAS:528:DyaK28XitVWltrw%3D (Pubitemid 26070065)
- (1996) Journal of Chromatography A , vol.724 , Issue.1-2 , pp. 358-363
- Martinsen, A.¹ Gynther, J.²

24
- 0033958868
- 4-Hydroxylated metabolites of the antiestrogens tamoxifen and toremifene are metabolized to unusually stable quinone methides
- DOI 10.1021/tx990144v
- PW Fan F Zhang JL Bolton 2000 Chem Res Toxicol 13 45 52 10.1021/tx990144v 1:CAS:528:DyaK1MXnvFKgtL0%3D (Pubitemid 30055958)
- (2000) Chemical Research in Toxicology , vol.13 , Issue.1 , pp. 45-52
- Fan, P.W.¹ Zhang, F.² Bolton, J.L.³

25
- 67449133537
- 10.1007/s00216-008-2586-7 1:CAS:528:DC%2BD1MXlvFymsA%3D%3D
- W Lohmann U Karst 2009 Anal Bioanal Chem 394 1341 1348 10.1007/s00216-008-2586-7 1:CAS:528:DC%2BD1MXlvFymsA%3D%3D
- (2009) Anal Bioanal Chem , vol.394 , pp. 1341-1348
- Lohmann, W.¹ Karst, U.²

26
- 47749104941
- New and old challenges of sports drug testing
- DOI 10.1002/jms.1455
- M Mazzarino I Fiacco X de la Torre F Botrè 2008 Eur J Mass Spectrom 43 903 907 10.1002/jms.1455 (Pubitemid 352029658)
- (2008) Journal of Mass Spectrometry , vol.43 , Issue.7 , pp. 903-907
- Botre, F.¹

27
- 77649243541
- 10.1002/rcm.4432 1:CAS:528:DC%2BC3cXjvFCntb8%3D
- M Mazzarino X de la Torre R Di Santo I Fiacco F Rosi F Botrè 2010 Rapid Commun Mass Spectrom 24 749 760 10.1002/rcm.4432 1:CAS:528: DC%2BC3cXjvFCntb8%3D
- (2010) Rapid Commun Mass Spectrom , vol.24 , pp. 749-760
- Mazzarino, M.¹ De La Torre, X.² Di Santo, R.³ Fiacco, I.⁴ Rosi, F.⁵ Botrè, F.⁶

28
- 52349087029
- 10.1007/s00216-008-2292-5 1:CAS:528:DC%2BD1cXhtFOru7vN
- M Mazzarino X de la Torre F Botrè 2008 Anal Bioanal Chem 392 681 698 10.1007/s00216-008-2292-5 1:CAS:528:DC%2BD1cXhtFOru7vN
- (2008) Anal Bioanal Chem , vol.392 , pp. 681-698
- Mazzarino, M.¹ De La Torre, X.² Botrè, F.³

29
- 77955983833
- The WADA Technical Document TD2009MRPL World Anti-Doping Agency, Montreal, Canada. Available at:
- The WADA Technical Document TD2009MRPL (2009) Minimum required performance level for detection of prohibited substances. World Anti-Doping Agency, Montreal, Canada. Available at: www.wada-ama.org
- (2009) Minimum Required Performance Level for Detection of Prohibited Substances

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.