Metabolic imprinting by prenatal, perinatal, and postnatal overnutrition: A review

Seminars in Reproductive Medicine

Volumn 29, Issue 3, 2011, Pages 266-276

  Dyer, Jennifer Shine ^a   Rosenfeld, Charles R ^b  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

cardiovascular disease; childhood obesity; chronic disease development; fetal origins hypothesis; gestational diabetes; LGA; macrosomia; metabolic imprinting; metabolic programming; obesity; Overnutrition; type 2 diabetes

Indexed keywords

ACETYLCHOLINE; APOLIPOPROTEIN A1; C PEPTIDE; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN;

BIRTH WEIGHT; BODY MASS; CALORIE; CARDIOVASCULAR DISEASE; ENVIRONMENTAL FACTOR; FETUS DEVELOPMENT; FETUS GROWTH; GLUCOSE BLOOD LEVEL; HUMAN; HYPERGLYCEMIA; HYPERTENSION; INSULIN RESISTANCE; INSULIN SENSITIVITY; MACRONUTRIENT; MACROSOMIA; MALNUTRITION; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; ORAL GLUCOSE TOLERANCE TEST; OVERNUTRITION; PERINATAL PERIOD; PREGNANCY; PREGNANCY DIABETES MELLITUS; PRENATAL PERIOD; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; RISK FACTOR; UNITED STATES; WEIGHT GAIN;

ADOLESCENT; ADULT; ANIMALS; CARDIOVASCULAR DISEASES; CHILD; CHILD DEVELOPMENT; CHILD, PRESCHOOL; DIABETES, GESTATIONAL; FEMALE; FETAL DEVELOPMENT; FETAL MACROSOMIA; HUMANS; INFANT; INFANT, NEWBORN; MALE; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; OVERNUTRITION; OVERWEIGHT; PREGNANCY; PREGNANCY COMPLICATIONS; PRENATAL EXPOSURE DELAYED EFFECTS; UNITED STATES; YOUNG ADULT;

EID: 79960515067     PISSN: 15268004     EISSN: 15264564     Source Type: Journal    
DOI: 10.1055/s-0031-1275521     Document Type: Review

References (75)

1. Freedman D S., Khan L K., Serdula M K., Ogden C L., Dietz W H. Racial and ethnic differences in secular trends for childhood BMI, weight, and height. Obesity (Silver Spring) 2006 14 2 301-308 (Pubitemid 46214762)
2. Hedley A A., Ogden C L., Johnson C L., Carroll M D., Curtin L R., Flegal K M. Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002. JAMA 2004 291 23 2847-2850 (Pubitemid 38747805)
3. Ogden C L., Carroll M D., Curtin L R., McDowell M A., Tabak C J., Flegal K M. Prevalence of overweight and obesity in the United States, 1999-2004. JAMA 2006 295 13 1549-1555
4. Jones K L. Role of obesity in complicating and confusing the diagnosis and treatment of diabetes in children. Pediatrics 2008 121 2 361-368 (Pubitemid 351198463)
5. Rewers M, LaPorte R E., King H, Tuomilehto J. Trends in the prevalence and incidence of diabetes: insulin-dependent diabetes mellitus in childhood. World Health Stat Q 1988 41 34 179-189 (Pubitemid 19034358)
6. Dabelea D, Hanson R L., Bennett P H., Roumain J, Knowler W C., Pettitt D J. Increasing prevalence of type II diabetes in American Indian children. Diabetologia 1998 41 8 904-910 (Pubitemid 28365976)
7. Dabelea D, Pettitt D J., Jones K L., Arslanian S A. Type 2 diabetes mellitus in minority children and adolescents. An emerging problem. Endocrinol Metab Clin North Am 1999 28 4 709-729, viii viii
8. Pihoker C, Scott C R., Lensing S Y., Cradock M M., Smith J. Non-insulin dependent diabetes mellitus in African-American youths of Arkansas. Clin Pediatr (Phila) 1998 37 2 97-102 (Pubitemid 28081272)
9. Pinhas-Hamiel O, Dolan L M., Daniels S R., Standiford D, Khoury P R., Zeitler P. Increased incidence of non-insulin-dependent diabetes mellitus among adolescents. J Pediatr 1996 128 5 Pt 1 608-615 (Pubitemid 26137717)
10. Scott C R., Smith J M., Cradock M M., Pihoker C. Characteristics of youth-onset noninsulin-dependent diabetes mellitus and insulin-dependent diabetes mellitus at diagnosis. Pediatrics 1997 100 1 84-91 (Pubitemid 27291013)
11. Liese A D., D'Agostino R B. Jr, Hamman R F. et al, SEARCH for Diabetes in Youth Study Group. The burden of diabetes mellitus among US youth: prevalence estimates from the SEARCH for Diabetes in Youth Study. Pediatrics 2006 118 4 1510-1518 (Pubitemid 46393797)
12. Wojcicki J M., Heyman M B. Let's Movechildhood obesity prevention from pregnancy and infancy onward. N Engl J Med 2010 362 16 1457-1459
13. Skinner A C., Steiner M J., Henderson F W., Perrin E M. Multiple markers of inflammation and weight status: cross-sectional analyses throughout childhood. Pediatrics 2010 125 4 e801-e809
14. Dyer J S., Rosenfeld C R., Rice J, Rice M, Hardin D S. Insulin resistance in Hispanic large-for-gestational-age neonates at birth. J Clin Endocrinol Metab 2007 92 10 3836-3843 (Pubitemid 47607631)
15. Barker D J. Fetal origins of coronary heart disease. BMJ 1995 311 6998 171-174
16. Dabelea D, Pettitt D J., Hanson R L., Imperatore G, Bennett P H., Knowler W C. Birth weight, type 2 diabetes, and insulin resistance in Pima Indian children and young adults. Diabetes Care 1999 22 6 944-950 (Pubitemid 29241050)
17. Pettitt D J., Aleck K A., Baird H R., Carraher M J., Bennett P H., Knowler W C. Congenital susceptibility to NIDDM. Role of intrauterine environment. Diabetes 1988 37 5 622-628
18. Eriksson J G., Forsen T J., Osmond C, Barker D JP. Pathways of infant and childhood growth that lead to type 2 diabetes. Diabetes Care 2003 26 11 3006-3010 (Pubitemid 37339490)
19. Lithell H O., McKeigue P M., Berglund L, Mohsen R, Lithell U B., Leon D A. Relation of size at birth to non-insulin dependent diabetes and insulin concentrations in men aged 50-60 years. BMJ 1996 312 7028 406-410 (Pubitemid 26055355)
20. Wei J N., Sung F C., Li C Y. et al. Low birth weight and high birth weight infants are both at an increased risk to have type 2 diabetes among schoolchildren in Taiwan. Diabetes Care 2003 26 2 343-348
21. Eriksson J G., Forsén T, Tuomilehto J, Jaddoe V WV, Osmond C, Barker D JP. Effects of size at birth and childhood growth on the insulin resistance syndrome in elderly individuals. Diabetologia 2002 45 3 342-348 (Pubitemid 34267356)
22. Eriksson J G., Forsén T, Tuomilehto J, Osmond C, Barker D JP. Early growth and coronary heart disease in later life: longitudinal study. BMJ 2001 322 7292 949-953 (Pubitemid 32374683)
23. Srinivasan M, Laychock S G., Hill D J., Patel M S. Neonatal nutrition: metabolic programming of pancreatic islets and obesity. Exp Biol Med (Maywood) 2003 228 1 15-23 (Pubitemid 36077623)
24. Fraser A, Tilling K, Macdonald-Wallis C et al. Association of maternal weight gain in pregnancy with offspring obesity and metabolic and vascular traits in childhood. Circulation 2010 121 23 2557-2564
25. Catalano P M. Obesity, insulin resistance, and pregnancy outcome. Reproduction 2010 140 3 365-371
26. Rasmussen K M. Yaktine A L. eds. Weight Gain During Pregnancy: Reexamining the Guidelines. Washington, DC National Academies Press 2009
27. Dabelea D, Pettitt D J. Intrauterine diabetic environment confers risks for type 2 diabetes mellitus and obesity in the offspring, in addition to genetic susceptibility. J Pediatr Endocrinol Metab 2001 14 8 1085-1091
28. Pettitt D J., Baird H R., Aleck K A., Bennett P H., Knowler W C. Excessive obesity in offspring of Pima Indian women with diabetes during pregnancy. N Engl J Med 1983 308 5 242-245 (Pubitemid 13174354)
29. Pettitt D J., Knowler W C., Bennett P H., Aleck K A., Baird H R. Obesity in offspring of diabetic Pima Indian women despite normal birth weight. Diabetes Care 1987 10 1 76-80 (Pubitemid 17069072)
30. Silverman B L., Rizzo T A., Cho N H., Metzger B E., The Northwestern University Diabetes in Pregnancy Center. Long-term effects of the intrauterine environment. Diabetes Care 1998 21 Suppl 2 B142-B149
31. Vohr B R., McGarvey S T., Tucker R. Effects of maternal gestational diabetes on offspring adiposity at 4-7 years of age. Diabetes Care 1999 22 8 1284-1291 (Pubitemid 29350238)
32. Centers for Disease Control and Prevention. Diabetes and Women's Health Across the Life Stages: A Public Health Perspective. Atlanta, GA U.S. Department of Health and Human Services, Centers for Disease Control and Prevention 2001
33. Pettitt D J., Aleck K A., Baird H R., Carraher M J., Bennett P H., Knowler W C. Congenital susceptibility to NIDDM. Role of intrauterine environment. Diabetes 1988 37 5 622-628
34. Metzger B E., Buchanan T A., Coustan D R. et al. Summary and recommendations of the Fifth International Workshop-Conference on Gestational Diabetes Mellitus. Diabetes Care 2007 30 Suppl 2 S251-S260 (Pubitemid 47036434)
35. DeFronzo R A., Bonadonna R C., Ferrannini E. Pathogenesis of NIDDM. A balanced overview. Diabetes Care 1992 15 3 318-368
36. Karam J H. Reversible insulin resistance in non-insulin-dependent diabetes mellitus. Horm Metab Res 1996 28 9 440-444 (Pubitemid 26343735)
37. Lyssenko V, Almgren P, Anevski D et al, Botnia study group. Predictors of and longitudinal changes in insulin sensitivity and secretion preceding onset of type 2 diabetes. Diabetes 2005 54 1 166-174 (Pubitemid 40105109)
38. Catalano P M., Tyzbir E D., Roman N M., Amini S B., Sims E A. Longitudinal changes in insulin release and insulin resistance in nonobese pregnant women. Am J Obstet Gynecol 1991 165 6 Pt 1 1667-1672
39. Catalano P M., Huston L, Amini S B., Kalhan S C. Longitudinal changes in glucose metabolism during pregnancy in obese women with normal glucose tolerance and gestational diabetes mellitus. Am J Obstet Gynecol 1999 180 4 903-916 (Pubitemid 29200557)
40. Catalano P M., Ehrenberg H M. The short- and long-term implications of maternal obesity on the mother and her offspring. BJOG 2006 113 10 1126-1133 (Pubitemid 44401205)
41. Center for Disease Control and Prevention. National Diabetes Fact Sheet. Atlanta, GA Center for Disease Control and Prevention 2007
42. Metzger B E., Gabbe S G., Persson B et al, International Association of Diabetes and Pregnancy Study Groups Consensus Panel. International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy. Diabetes Care 2010 33 3 676-682
43. Kim C, Newton K M., Knopp R H. Gestational diabetes and the incidence of type 2 diabetes: a systematic review. Diabetes Care 2002 25 10 1862-1868
44. Metzger B E., Lowe L P., Dyer A R. et al, HAPO Study Cooperative Research Group. Hyperglycemia and adverse pregnancy outcomes. N Engl J Med 2008 358 19 1991-2002 (Pubitemid 351656454)
45. Langer O, Yogev Y, Xenakis E M., Rosenn B. Insulin and glyburide therapy: dosage, severity level of gestational diabetes, and pregnancy outcome. Am J Obstet Gynecol 2005 192 1 134-139 (Pubitemid 40164232)
46. Dabelea D. The predisposition to obesity and diabetes in offspring of diabetic mothers. Diabetes Care 2007 30 Suppl 2 S169-S174 (Pubitemid 47036421)
47. Vohr B R., McGarvey S T., Tucker R. Effects of maternal gestational diabetes on offspring adiposity at 4-7 years of age. Diabetes Care 1999 22 8 1284-1291 (Pubitemid 29350238)
48. Schaefer-Graf U M., Pawliczak J, Passow D et al. Birth weight and parental BMI predict overweight in children from mothers with gestational diabetes. Diabetes Care 2005 28 7 1745-1750 (Pubitemid 40923087)
49. Crowther C A., Hiller J E., Moss J R., McPhee A J., Jeffries W S., Robinson J S., Australian Carbohydrate Intolerance Study in Pregnant Women (ACHOIS) Trial Group. Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. N Engl J Med 2005 352 24 2477-2486 (Pubitemid 41007863)
50. O'Sullivan J B., Gellis S S., Dandrow R V., Tenney B O. The potential diabetic and her treatment in pregnancy. Obstet Gynecol 1966 27 5 683-689
51. Hillier T A., Pedula K L., Schmidt M M., Mullen J A., Charles M A., Pettitt D J. Childhood obesity and metabolic imprinting: the ongoing effects of maternal hyperglycemia. Diabetes Care 2007 30 9 2287-2292 (Pubitemid 47359033)
52. Pettitt D J., Knowler W C., Bennett P H., Aleck K A., Baird H R. Obesity in offspring of diabetic Pima Indian women despite normal birth weight. Diabetes Care 1987 10 1 76-80 (Pubitemid 17069072)
53. Catalano P M., Farrell K, Thomas A et al. Perinatal risk factors for childhood obesity and metabolic dysregulation. Am J Clin Nutr 2009 90 5 1303-1313
54. Catalano P M., Thomas A, Huston-Presley L, Amini S B. Increased fetal adiposity: a very sensitive marker of abnormal in utero development. Am J Obstet Gynecol 2003 189 6 1698-1704 (Pubitemid 38056447)
55. Sewell M F., Huston-Presley L, Super D M., Catalano P M. Increased neonatal fat mass, not lean body mass, is associated with maternal obesity. Am J Obstet Gynecol 2006 195 4 1100-1103 (Pubitemid 44415658)
56. Catalano P M., Drago N M., Amini S B. Maternal carbohydrate metabolism and its relationship to fetal growth and body composition. Am J Obstet Gynecol 1995 172 5 1464-1470
57. Boerschmann H, Pflüger M, Henneberger L, Ziegler A G., Hummel S. Prevalence and predictors of overweight and insulin resistance in offspring of mothers with gestational diabetes mellitus. Diabetes Care 2010 33 8 1845-1849
58. Frazao E ed. America's eating habits: changes and consequences [Agricultural Informational Bulletin No. 750]. Washington, DC U.S. Department of Agriculture/Economic Research Service 1999
59. Guo F, Jen K L. High-fat feeding during pregnancy and lactation affects offspring metabolism in rats. Physiol Behav 1995 57 4 681-686
60. Holemans K, Caluwaerts S, Poston L, Van Assche F A. Diet-induced obesity in the rat: a model for gestational diabetes mellitus. Am J Obstet Gynecol 2004 190 3 858-865 (Pubitemid 38406804)
61. Accurso A, Bernstein R K., Dahlqvist A et al. Dietary carbohydrate restriction in type 2 diabetes mellitus and metabolic syndrome: time for a critical appraisal. Nutr Metab (Lond) 2008 5 5 9
62. Reaven G M. Effect of dietary carbohydrate on the metabolism of patients with non-insulin dependent diabetes mellitus. Nutr Rev 1986 44 2 65-73
63. Garg A, Bantle J P., Henry R R. et al. Effects of varying carbohydrate content of diet in patients with non-insulin-dependent diabetes mellitus. JAMA 1994 271 18 1421-1428
64. Kaung H L. Growth dynamics of pancreatic islet cell populations during fetal and neonatal development of the rat. Dev Dyn 1994 200 2 163-175
65. Patel M S., Srinivasan M. Metabolic programming: causes and consequences. J Biol Chem 2002 277 3 1629-1632 (Pubitemid 34968729)
66. Raab E L., Vuguin P M., Stoffers D A., Simmons R A. Neonatal exendin-4 treatment reduces oxidative stress and prevents hepatic insulin resistance in intrauterine growth-retarded rats. Am J Physiol Regul Integr Comp Physiol 2009 297 6 R1785-R1794
67. Pettitt D J., Forman M R., Hanson R L., Knowler W C., Bennett P H. Breastfeeding and incidence of non-insulin-dependent diabetes mellitus in Pima Indians. Lancet 1997 350 9072 166-168 (Pubitemid 27303622)
68. Yajnik C S. Early life origins of insulin resistance and type 2 diabetes in India and other Asian countries. J Nutr 2004 134 1 205-210 (Pubitemid 38057450)
69. Elks C E., Loos R J., Sharp S J. et al. Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth. PLoS Med 2010 7 5 e1000284
70. Dewey K G. Growth characteristics of breast-fed compared to formula-fed infants. Biol Neonate 1998 74 2 94-105 (Pubitemid 28377139)
71. Stettler N, Stallings V A., Troxel A B. et al. Weight gain in the first week of life and overweight in adulthood: a cohort study of European American subjects fed infant formula. Circulation 2005 111 15 1897-1903 (Pubitemid 40570209)
72. Knowler W C., Barrett-Connor E, Fowler S E. et al, Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002 346 6 393-403 (Pubitemid 34437694)
73. Vadlamudi S, Kalhan S C., Patel M S. Persistence of metabolic consequences in the progeny of rats fed a HC formula in their early postnatal life. Am J Physiol 1995 269 4 Pt 1 E731-E738
74. Monk M. Epigenetic programming of differential gene expression in development and evolution. Dev Genet 1995 17 3 188-197
75. Jacob R A. Folate, DNA methylation, and gene expression: factors of nature and nurture. Am J Clin Nutr 2000 72 4 903-904