Development of a transgenic zebrafish model expressing GFP in the notochord, somite and liver directed by the hfe2 gene promoter

Transgenic Research

Volumn 20, Issue 4, 2011, Pages 787-798

  Bian, Yue Hong ^a,b   Xu, Cheng ^a   Li, Junling ^a   Xu, Jin ^a   Zhang, Hongwei ^b   Du, Shao Jun ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Hemojuvelin; HFE2; Liver; RGM; Transgenic fish; Zebrafish

Indexed keywords

FATTY ACID BINDING PROTEIN; FATTY ACID BINDING PROTEIN 10, ZEBRAFISH; FATTY ACID-BINDING PROTEIN 10, ZEBRAFISH; GREEN FLUORESCENT PROTEIN; HEMOJUVELIN PROTEIN, ZEBRAFISH; TRANSACTIVATOR PROTEIN; VALPROIC ACID; ZEBRAFISH PROTEIN;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ANIMAL; ANIMAL MODEL; ARTICLE; CLASSIFICATION; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HEMOCHROMATOSIS; HUMAN; LIVER; METABOLISM; MOLECULAR GENETICS; NOTOCHORD; PHYLOGENY; PROMOTER REGION; SOMITE; TRANSGENIC ANIMAL; ZEBRA FISH;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; FATTY ACID-BINDING PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GREEN FLUORESCENT PROTEINS; HEMOCHROMATOSIS; HUMANS; LIVER; MODELS, ANIMAL; MOLECULAR SEQUENCE DATA; NOTOCHORD; PHYLOGENY; PROMOTER REGIONS, GENETIC; SOMITES; TRANS-ACTIVATORS; VALPROIC ACID; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO;

EID: 79960471805     PISSN: 09628819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11248-010-9465-7     Document Type: Article

References (22)

1. Beutler E (2006) Hemochromatosis: genetics and pathophysiology. Annu Rev Med 57: 331-347.
2. Brakensiek K, Fegbeutel C, Mälzer M, Strüber M, Kreipe H, Stuhrmann M (2009) Juvenile hemochromatosis due to homozygosity for the G320 V mutation in the HJV gene with fatal outcome. Clin Genet 76(5): 493-495.
3. Camus LM, Lambert LA (2007) Molecular evolution of hemojuvelin and the repulsive guidance molecule family. J Mol Evol 65(1): 68-81.
4. Constante M, Wang D, Raymond VA, Bilodeau M, Santos MM (2007) Repression of repulsive guidance molecule C during inflammation is independent of Hfe and involves tumor necrosis factor-alpha. Am J Pathol 170(2): 497-504.
5. Du SJ, Dienhart M (2001) Zebrafish tiggy-winkle hedgehog promoter directs notochord and floor plate green fluorescence protein expression in transgenic zebrafish embryos. Dev Dyn 222(4): 655-666.
6. Du SJ, Li H, Bian YH, Zhong Y (2008) Heat shock protein 90a1 is required for organized myofibril assembly in skeletal muscles of zebrafish embryos. Proc Natl Academy Sci USA 105(2): 554-559.
7. Farooq M, Sulochana KN, Pan X, To J, Sheng D, Gong Z, Ge R (2008) Histone deacetylase 3 (hdac3) is specifically required for liver development in zebrafish. Dev Biol 317(1): 336-353.
8. Field HA, Ober EA, Roeser T, Stainier DY (2003) Formation of the digestive system in zebrafish. I. Liver morphogenesis. Dev Biol 253(2): 279-290.
9. Her GM, Chiang CC, Chen WY, Wu JL (2003) In vivo studies of liver-type fatty acid binding protein (L-FABP) gene expression in liver of transgenic zebrafish (Danio rerio). FEBS Lett 538(1-3): 125-133.
10. Huang FW, Pinkus JL, Pinkus GS, Fleming MD, Andrews NC (2005) A mouse model of juvenile hemochromatosis. J Clin Invest 115(8): 2187-2191.
11. Krijt J, Vokurka M, Chang KT, Necas E (2004) Expression of Rgmc, the murine ortholog of hemojuvelin gene, is modulated by development and inflammation, but not by iron status or erythropoietin. Blood 104(13): 4308-4310.
12. Lanzara C, Roetto A, Daraio F, Rivard S, Ficarella R, Simard H, Cox TM, Cazzola M, Piperno A, Gimenez-Roqueplo AP, Grammatico P, Volinia S, Gasparini P, Camaschella C (2004) Spectrum of hemojuvelin gene mutations in 1q-linked juvenile hemochromatosis. Blood 103(11): 4317-4321.
13. Malyszko J (2009) Hemojuvelin: the hepcidin story continues. Kidney Blood Press Res. 32(2): 71-76.
14. Monnier PP, Sierra A, Macchi P, Deitinghoff L, Andersen JS, Mann M, Flad M, Hornberger MR, Stahl B, Bonhoeffer F, Mueller BK (2002) RGM is a repulsive guidance molecule for retinal axons. Nature 419(6905): 392-395.
15. Niederkofler V, Salie R, Sigrist M, Arber S (2004) Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system. J Neurosci 24(4): 808-818.
16. Niederkofler V, Salie R, Arber S (2005) Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload. J Clin Invest 115(8): 2180-2186.
17. Oldekamp J, Krämer N, Alvarez-Bolado G, Skutella T (2004) Expression pattern of the repulsive guidance molecules RGM A, B and C during mouse development. Gene Expr Patterns 4(3): 283-288.
18. Papanikolaou G, Samuels ME, Ludwig EH, MacDonald ML, Franchini PL, Dubé MP, Andres L, MacFarlane J, Sakellaropoulos N, Politou M, Nemeth E, Thompson J, Risler JK, Zaborowska C, Babakaiff R, Radomski CC, Pape TD, Davidas O, Christakis J, Brissot P, Lockitch G, Ganz T, Hayden MR, Goldberg YP (2004) Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. Nat Genet 36(1): 77-82.
19. Rodriguez A, Pan P, Parkkila S (2007) Expression studies of neogenin and its ligand hemojuvelin in mouse tissues. J Histochem Cytochem 55(1): 85-96.
20. Samad TA, Srinivasan A, Karchewski LA, Jeong SJ, Campagna JA, Ji RR, Fabrizio DA, Zhang Y, Lin HY, Bell E, Woolf CJ (2004) DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties. J Neurosci 24(8): 2027-2036.
21. Schmidtmer J, Engelkamp D (2004) Isolation and expression pattern of three mouse homologues of chick Rgm. Gene Expr Patterns 4(1): 105-110.
22. Severyn CJ, Shinde U, Rotwein P (2009) Molecular biology, genetics and biochemistry of the repulsive guidance molecule family. Biochem J 422(3): 393-403.