Production of monoclonal antibodies against antitumor cyclohexapeptide RA-VII from Rubia cordifolia and their characterization

Journal of Natural Medicines

Volumn 65, Issue 3-4, 2011, Pages 588-593

  Hasuda, Tomoyo ^a   Hitotsuyanagi, Yukio ^a   Takeya, Koichi ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Cross reactivity; Cyclic hexapeptide; Monoclonal antibody; Rubia cordifolia

Indexed keywords

BOVINE SERUM ALBUMIN; CYCLOHEXAPEPTIDE RA VII; HAPTEN; HEXAPEPTIDE; HUMAN SERUM ALBUMIN; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN M ANTIBODY; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIBODY TITER; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; CROSS REACTION; DRUG STRUCTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; HYBRIDOMA; IC 50; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOUSE; MYELOMA CELL; NONHUMAN; RUBIA; RUBIA AKANE; RUBIA CORDIFOLIA; SENSITIVITY AND SPECIFICITY; SPLEEN CELL;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; ANTINEOPLASTIC AGENTS; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOASSAY; MALE; MICE; MICE, INBRED BALB C; OLIGOPEPTIDES; PEPTIDES, CYCLIC; RUBIA; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 79960460437     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-011-0508-z     Document Type: Article

References (19)

1. H Itokawa K Takeya K Mihara N Mori T Hamanaka T Sonobe Y Iitaka 1983 Studies on the antitumor cyclic hexapeptides obtained from Rubiae radix Chem Pharm Bull 31 1424 1427 6627519 1:CAS:528:DyaL3sXltVWis7k%3D (Pubitemid 13061531)
2. H Itokawa K Takeya N Mori T Hamanaka T Sonobe K Mihara 1984 Isolation and antitumor activity of cyclic hexapeptides isolated from Rubiae radix Chem Pharm Bull 32 284 290 6722954 1:CAS:528:DyaL2cXhsFSks7s%3D (Pubitemid 14195367)
3. Itokawa H, Takeya K, Hitotsuyanagi Y, Morita H (1997) Macrocyclic peptide alkaloids from plants. In: Cordell GA (ed) The alkaloids, vol 49. Academic Press, New York, pp 301-387
4. SD Jolad JJ Hoffmann SJ Torrance RM Wiedhopf JR Cole SK Arora RB Bates RL Gargiulo GR Kriek 1977 Bouvardin and deoxybouvardin, antitumor cyclic hexapeptides from Bouvardia ternifolia (Rubiaceae) J Am Chem Soc 99 8040 8044 10.1021/ja00466a043 591683 10.1021/ja00466a043 1:CAS:528:DyaE1cXktFGrsg%3D%3D (Pubitemid 8236779)
5. K Inoue T Mukaiyama T Kobayashi M Ogawa 1986 Activity of RA-700, a cyclic hexapeptide from Rubiae Radix, in the human tumor clonogenic assay Invest New Drugs 4 231 236 10.1007/BF00179588 3818226 10.1007/BF00179588 1:CAS:528:DyaL2sXpsFOgug%3D%3D (Pubitemid 17205951)
6. H Majima S Tukagoshi H Furue M Suminaga K Sakamoto N Nukaria K Uematsu T Furuta M Kurihara A Yoshida S Isomura T Takemoto M Hirashima T Izumi I Nakao Y Ohashi K Ito R Asai 1993 Jpn J Cancer Chemother 20 67 78 1:STN:280: DyaK3s7jsFGktQ%3D%3D
7. M Zalacaín E Zaera D Vázquez A Jiménez 1982 The mode of action of the antitumor drug bouvardin, an inhibitor of protein synthesis in eukaryotic cells FEBS Lett 148 95 97 10.1016/0014-5793(82)81250-7 6924616 10.1016/0014-5793(82)81250-7 (Pubitemid 13225241)
8. BV Sirdeshpande PL Toogood 1995 Inhibition of protein synthesis by RA-VII Bioorg Chem 23 460 470 10.1006/bioo.1995.1032 10.1006/bioo.1995.1032 1:CAS:528:DyaK28XkvV2ktQ%3D%3D (Pubitemid 26029463)
9. 2 arrest by the inhibition of cytokinesis Cancer Lett 209 223 229 10.1016/j.canlet.2003.12.022 15159025 10.1016/j.canlet.2003.12.022 1:CAS:528:DC%2BD2cXktF2ksr4%3D (Pubitemid 38670492)
10. R Sakata Y Shoyama H Murakami 1994 Production of monoclonal antibodies and enzyme immunoassay for typical adenylate cyclase activator, forskolin Cytotechnology 16 101 108 10.1007/BF00754612 7765788 10.1007/BF00754612 1:STN:280:DyaK2M7ltFCmtg%3D%3D
11. H Yanagihara R Sakata Y Shoyama H Murakami 1996 Rapid analysis of small samples containing forskolin using monoclonal antibodies Planta Med 62 169 172 8657754 10.1055/s-2006-957844 1:CAS:528:DyaK28XjtlOhur4%3D (Pubitemid 26163225)
12. Y Shoyama T Fukada H Murakami 1996 Production of monoclonal antibodies and ELISA for thebaine and codeine Cytotechnology 19 55 61 10.1007/BF00749755 10.1007/BF00749755
13. H Tanaka Y Goto Y Shoyama 1996 Monoclonal antibody based enzyme immunoassay for marihuana (cannabinoid) compounds J Immunoassay 17 321 342 8957763 10.1080/01971529608005796 1:CAS:528:DyaK28XnsVCmsbc%3D (Pubitemid 26404780)
14. M Ishiyama Y Shoyama H Murakami H Shinohara 1996 Production of monoclonal antibodies and development of an ELISA for solamargine Cytotechnology 18 153 158 10.1007/BF00767762 10.1007/BF00767762 (Pubitemid 3044099)
15. H Itokawa K Takeya N Mori T Sonobe S Mihashi T Hamanaka 1986 Studies on antitumor cyclic hexapeptides RA obtained from Rubiae Radix, Rubiaceae. VI. Minor antitumor constituents Chem Pharm Bull 34 3762 3768 3815597 1:CAS:528:DyaL2sXkslWrug%3D%3D (Pubitemid 17192766)
16. H Itokawa H Morita K Takeya N Tomioka A Tomioka Y Iitaka 1991 New antitumor bicyclic hexapeptides, RA-VI and -VIII from Rubia cordifolia; conformation-activity relationship II Tetrahedron 47 7007 7020 10.1016/S0040-4020(01)96155-1 10.1016/S0040-4020(01)96155-1 1:CAS:528: DyaK38XhtValtr4%3D
17. O Morinaga H Tanaka Y Shoyama 2000 Production of monoclonal antibody against a major purgative component, sennoside A, its characterization and ELISA Analyst 125 1109 1113 10.1039/B000988L 10.1039/b000988l 1:CAS:528: DC%2BD3cXjslWltbs%3D (Pubitemid 30392248)
18. EW Weiler MH Zenk 1976 Use of immunoassay in plant science. Part 1. Radioimmunoassay for the determination of digoxin and related compounds in Digitalis lanata Phytochemistry 15 1537 1545 10.1016/S0031-9422(00)88933-5 10.1016/S0031-9422(00)88933-5 1:CAS:528:DyaE2sXitFyhsQ%3D%3D
19. H Tanaka Y Shoyama 1998 Formation of a monoclonal antibody against glycyrrhizin and development of an ELISA Biol Pharm Bull 21 1391 1393 9881664 1:CAS:528:DyaK1MXivFyg (Pubitemid 29021811)