Spatiotemporal modeling and analysis of transient gene delivery

Biotechnology and Bioengineering

Volumn 108, Issue 9, 2011, Pages 2205-2217

  Jandt, Uwe ^a   Shao, Shi ^a   Wirth, Manfred ^b   Zeng, An Ping ^a  

^a HAMBURG UNIVERSITY OF TECHNOLOGY   (Germany)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Compartmentalization; Intracellular transport; Spatiotemporal modeling; Transient transfection dynamics

Indexed keywords

CELL LINES; CELL MORPHOLOGY; COMPARTMENTALIZATION; CONFOCAL IMAGING; GENE DELIVERY; HEK293 CELLS; INDUSTRIAL PROTEINS; INTRACELLULAR TRANSPORT; MICROTUBULES; NOVEL PLASMIDS; PREDICTION AND ANALYSIS; QUANTITATIVE POLYMERASE CHAIN REACTION; SENSITIVE PARAMETER; SIMULATED RESULTS; SPATIOTEMPORAL MODELING; STOCHASTIC MODELING; TRANSFECTION EFFICIENCY; TRANSIENT GENE EXPRESSIONS; TRANSIENT TRANSFECTION; TRANSIENT TRANSFECTION DYNAMICS; TRANSPORT PARAMETERS;

CELL CULTURE; DNA; GENE THERAPY; GENE TRANSFER; IDENTIFICATION (CONTROL SYSTEMS); PARAMETER ESTIMATION; POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS;

GENE EXPRESSION;

ARTICLE; CELL STRAIN HEK293; CELL STRUCTURE; CELL TRANSPORT; CONTROLLED STUDY; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MICROTUBULE; POLYMERASE CHAIN REACTION; QUANTITATIVE ANALYSIS;

ALGORITHMS; CELL NUCLEUS; DNA REPLICATION; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; HEK293 CELLS; HUMANS; MICROSCOPY, CONFOCAL; MICROTUBULE-ORGANIZING CENTER; MICROTUBULES; MODELS, BIOLOGICAL; PLASMIDS; POLYMERASE CHAIN REACTION; SYSTEMS BIOLOGY; TRANSFECTION;

EID: 79960459965     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.23175     Document Type: Article

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