Human knee synovial fluid cytokines correlated with grade of knee osteoarthritis: A pilot study

Bulletin of the NYU Hospital for Joint Diseases

Volumn 69, Issue 2, 2011, Pages 122-127

  Thomas Vangsness, Jr ^a   Burke, Wendy S ^b   Narvy, Steven J ^a   MacPhee, Robert D ^a   Fedenko, Alexander N ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12P70; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 1;

ADOLESCENT; ADULT; AGED; ARTHROSCOPY; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE DEGENERATION; CLINICAL ARTICLE; CLINICAL ASSESSMENT TOOL; FEMALE; FLOW CYTOMETRY; HUMAN; IMMUNOASSAY; INTERNATIONAL CARTILAGE REPAIR SOCIETY CLASSIFICATION; JOINT BIOPSY; KELLGREN LAWRENCE CLASSIFICATION; KNEE MENISCUS RUPTURE; KNEE OSTEOARTHRITIS; MALE; MENISCECTOMY; SYNOVIAL FLUID;

ADOLESCENT; ADULT; AGED; ARTHROSCOPY; BIOLOGICAL MARKERS; BIOPSY; CARTILAGE, ARTICULAR; CHEMOKINE CCL2; CHEMOKINE CCL3; CYTOKINES; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOASSAY; INTERLEUKIN-2; INTERLEUKIN-5; LOS ANGELES; MALE; MIDDLE AGED; OSTEOARTHRITIS, KNEE; PILOT PROJECTS; SEVERITY OF ILLNESS INDEX; SYNOVIAL FLUID; SYNOVIAL MEMBRANE; UP-REGULATION;

EID: 79960438563     PISSN: 19369719     EISSN: 19369727     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Cotran RS, Kumar V, Collins T. Pathologic Basis of Disease (6th ed). Philadelphia: WB Saunders Company. 1999.
2. Kaplan LA, Pesce AJ, Kazmierczak SC. Extravascular biological fluids. In: Clinical Chemistry: Theory, Analysis, Correlation (4th ed). St. Louis: Mosby, 2003, pp. 784-785.
3. Seeley RR, Stephens TD, Tate P. Anatomy and Physiology (7th ed). New York: McGraw-Hill College, 2004.
4. Mazzetti I, Grigolo B, Pulsatelli L, et al. Differential roles of nitric oxide and oxygen radicals in chondrocytes affected by osteoarthritis and rheumatoid arthritis. Clin Sci (Lond). 2001 Dec;101(6):593-599.
5. Goodman CC, Fuller KS, Boissonnault WG. Pathology: Implications for the Physical Therapist (2nd ed). Philadelphia: Saunders, 2003.
6. Pagura SMC, Thomas SG, Woodhouse LJ, et al. Circulating and synovial levels of IGF-1, cytokines, physical function and anthropometry differ in women awaiting total knee arthroplasty when compared to men. J Orthop Res. 2005;23:397-405.
7. Goldring MB. The role of the chondrocyte in osteoarthritis. Arthritis Rheum. 2000;43(9):1916-1926.
8. Olee T, Hashimoto S, Quach J, et al. IL-18 is produced by articular chondrocytes and induces proinflammatory and catabolic responses. J Immunol. 1999;162:1096-100.
9. Fernandes JC, Martel-Pelletier J, Pelletier JP. The role of cytokines in osteoarthritis pathophysiology. Biorheology. 2002;39(1-2):237-246.
10. Caron JP, Fernandes JC, Martel-Pelletier J, et al. Chondroprotective effect of intraarticular injections of interleukin-1 antagonist in experimental osteoarthritis: suppression of collagenase- 1 expression. Arthritis Rheum. 1996;39:1535-1544.
11. Notoya K, Jovanovic DV, Reboul P, et al. The induction of cell death in human osteoarthritis chondrocytes by nitric oxide isrelated to the production of prostaglandin E2 via the induction of cyclooxygenase-2. J Immunol. 2000;165:3402-3410.
12. Goldring SR, Goldring MB. The role of cytokines in cartilage matrix degradation in osteoarthritis. Clin Orthop Relat Res. 2004 Oct;(427 Suppl):S27-S36.
13. Kellgren JH, Lawrence JS. Radiologic assessment of osteoarthrosis. Ann Rheum Dis. 1957 Dec;16:494-502.
14. Brittberg M, Winalski CS. Evaluation of cartilage injuries and repair. J Bone Joint Surg Am. 2003:85(Suppl 2):58-69.
15. Raza K, Falciani F, Curnow SJ, et al. Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin. Arthritis Res Ther. 2005;7(4):R784-95.
16. Martins TB, Pasi BM, Pickering JW, et al. Determination of cytokine responses using a multiplexed fluorescent microsphere immunoassay. Am J Clin Pathol. 2002 Sep;118(3):346-53.
17. Fulton RJ, McDade RL, Smith PL, et al. Advanced multiplexed analysis with the FlowMetrix system. Clin Chem. 1997 Sep;43(9):1749-56.
18. Oliver KG, Kettman JR, Fulton RJ. Multiplexed analysis of human cytokines by use of the FlowMetrix system. Clin Chem. 1998 Sep;44(9):2057-60.
19. Carson RT, Vignali DA. Simultaneous quantitation of 15 cytokines using a multiplexed flow cytometric assay. J Immunol Methods. 1999 Jul 30;227(1-2):41-52.
20. DuPont NC, Wang K, Wadhwa PD, et al. Validation and comparison of luminex multiplex cytokine analysis kits with ELISA: determinations of a panel of nine cytokines in clinical sample culture supernatants. J Reprod Immunol. 2005 Aug;66(2):175-91.
21. Ray CA, Bowsher RR, Smith WC, et al. Development, validation, and implementation of a multiplex immunoassay for the simultaneous determination of five cytokines in human serum. J Pharm Biomed Anal. 2005,36(5):1037-44.
22. Khan SS, Smith MS, Reda D, et al. Multiplex bead array assays for detection of soluble cytokines: comparisons of sensitivity and quantitative values among kits from multiple manufacturers. Cytometry B Clin Cytom. 2004 Sep;61(1):35-9.
23. Hildesheim A, Ryan RL, Rinehart E, et al. Simultaneous measurement of several cytokines using small volumes of biospecimens. Cancer Epidemiol Biomarkers Prev. 2002, 11(11):1477-84.
24. Cameron M, Buchgraber A, Passler H, et al. The natural history of the anterior cruciate ligament-deficient knee. Am J Sports Med. 1997 Nov-Dec;25(6):751-754.
25. Smith MD, Triantafillou S, Parker A, et al. Synovial membrane inflammation and cytokine production in patients with early osteoarthritis. J Rheumatol. 1997;24:365-371.