Proteomics, ultrastructure, and physiology of hippocampal synapses in a fragile X syndrome mouse model reveal presynaptic phenotype

Journal of Biological Chemistry

Volumn 286, Issue 29, 2011, Pages 25495-25504

  Klemmer, Patricia ^a   Meredith, Rhiannon M ^a   Holmgren, Carl D ^a,c   Klychnikov, Oleg I ^a   Stahl Zeng, Jianru ^b   Loos, Maarten ^a   Van Der Schors, Roel C ^a   Wortel, Joke ^a   De Wit, Heidi ^a   Spijker, Sabine ^a   Rotaru, Diana C ^a   Mansvelder, Huibert D ^a   Smit, August B ^a   Li, Ka Wan ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b MDS SCIEX   (Canada)

^c Turing Center for Living Systems CENTURI Aix Marseille University   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE ZONE; CELL DIFFERENTIATION; FALSE DISCOVERY RATE; FRAGILE X MENTAL RETARDATION PROTEINS; GROWTH CONES; IMMUNOBLOTTING; IN-LINE; KNOCK OUTS; MENTAL RETARDATION; MOUSE MODELS; NEURITE OUTGROWTH; POSTSYNAPTIC DENSITIES; PRESYNAPTIC; PROTEIN SYNTHESIS; PROTEOMICS; Q-VALUES; QUANTITATIVE PROTEOMICS; SECOND GROUP; SHORT TERM PLASTICITY; SYNAPTIC VESICLE; ULTRASTRUCTURAL ANALYSIS; WILD TYPES; X SYNDROME;

BIOSYNTHESIS; GENES; HANDICAPPED PERSONS; LAKES; MAMMALS; MOLECULAR BIOLOGY;

PROTEINS;

GROWTH FACTOR; NEUROMODULIN; PROTEIN BASP1; PROTEIN CEND1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; FEMALE; FRAGILE X SYNDROME; GROWTH CONE; HIPPOCAMPUS; MOUSE; NERVE ENDING; NERVE FIBER GROWTH; NONHUMAN; PHENOTYPE; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; QUANTITATIVE ANALYSIS; SYNAPSE; SYNAPSE VESICLE; SYNAPTOGENESIS; ULTRASTRUCTURE; UPREGULATION; WILD TYPE;

ACTINS; ANIMALS; CA1 REGION, HIPPOCAMPAL; CELL DIFFERENTIATION; CYTOSKELETON; DISEASE MODELS, ANIMAL; EXCITATORY POSTSYNAPTIC POTENTIALS; FRAGILE X MENTAL RETARDATION PROTEIN; FRAGILE X SYNDROME; GENE KNOCKOUT TECHNIQUES; HIPPOCAMPUS; MICE; NEURITES; NEURONAL PLASTICITY; PHENOTYPE; PROTEOMICS; PSEUDOPODIA; SYNAPSES; SYNAPTIC VESICLES; TANDEM MASS SPECTROMETRY;

MUS;

EID: 79960424316     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.210260     Document Type: Article

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