Severity of head injury is associated with increased risk of coagulopathy in combat casualties

Journal of Trauma - Injury, Infection and Critical Care

Volumn 71, Issue SUPPL. 1, 2011, Pages

  Cap, Andrew Peter ^a   Spinella, Philip C ^a  

^a US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

Author keywords

Coagulopathy; Combat; ortality; Trauma; Traumatic brain injury

Indexed keywords

RECOMBINANT BLOOD CLOTTING FACTOR 7A;

ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; AFGHANISTAN; ARTICLE; BATTLE INJURY; BLOOD CLOTTING DISORDER; BLOOD TRANSFUSION; COMPARATIVE STUDY; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; GLASGOW COMA SCALE; HEAD INJURY; HEART INFARCTION; HUMAN; INJURY SCALE; INJURY SEVERITY; IRAQ; KIDNEY FAILURE; LUNG EMBOLISM; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; STEP WISE MULTIPLE REGRESSION; STROKE; SYSTOLIC BLOOD PRESSURE; TRAUMATIC BRAIN INJURY; UNITED STATES;

ABBREVIATED INJURY SCALE; ADULT; AFGHAN CAMPAIGN 2001-; BLOOD COAGULATION DISORDERS; BLOOD TRANSFUSION; BRAIN INJURIES; GLASGOW COMA SCALE; HUMANS; IRAQ WAR, 2003 -; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES; RISK FACTORS; STATISTICS, NONPARAMETRIC; YOUNG ADULT;

EID: 79960422974     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e3182218cd8     Document Type: Article

References (20)

1. Dewall J. The ABCs of TBI. Evidence-based guidelines for adult traumatic brain injury care. JEMS. 2010;35:54-61; quiz 63.
2. Kelly JF, Ritenour AE, McLaughlin DF, et al. Injury severity and causes of death from Operation Iraqi Freedom and Operation Enduring Freedom: 2003-2004 versus 2006. J Trauma. 2008;64(suppl 2):S21-S26; discussion S26-S27.
3. Harhangi BS, Kompanje EJ, Leebeek FW, Maas AI. Coagulation disorders after traumatic brain injury. Acta Neurochir (Wien). 2008;150: 165-175; discussion 175.
4. Niles SE, McLaughlin DF, Perkins JG, et al. Increased mortality associated with the early coagulopathy of trauma in combat casualties. J Trauma. 2008;64:1459-1463; discussion 1463-1455.
5. Brohi K, Cohen MJ, Ganter MT, Matthay MA, Mackersie RC, Pittet JF. Acute traumatic coagulopathy: initiated by hypoperfusion: modulated through the protein C pathway? Ann Surg. 2007;245:812-818. (Pubitemid 46684113)
6. Park MS, Martini WZ, Dubick MA, et al. Thromboelastography as a better indicator of hypercoagulable state after injury than prothrombin time or activated partial thromboplastin time. J Trauma. 2009;67:266- 275; discussion 275-276.
7. Dunbar NM, Chandler WL. Thrombin generation in trauma patients. Transfusion. 2009;49:2652-2660.
8. Jeger V, Urwyler N, Zimmermann H, Exadaktylos AK. Trauma-induced coagulopathy in severely injured patients: knowledge lost in translation? Emerg Med J. 2010;27:551-552.
9. Holcomb JB, Jenkins D, Rhee P, et al. Damage control resuscitation: directly addressing the early coagulopathy of trauma. J Trauma. 2007; 62:307-310.
10. Spinella PC, Holcomb JB. Resuscitation and transfusion principles for traumatic hemorrhagic shock. Blood Rev. 2009;23:231-240.
11. Lustenberger T, Talving P, Kobayashi L, et al. Time course of coagulopathy in isolated severe traumatic brain injury. Injury. May 12, 2010. ePub ahead of print.
12. Talving P, Benfield R, Hadjizacharia P, Inaba K, Chan LS, Demetriades D. Coagulopathy in severe traumatic brain injury: a prospective study. J Trauma. 2009;66:55- 61; discussion 61-62.
13. Lustenberger T, Talving P, Kobayashi L, et al. Early coagulopathy after isolated severe traumatic brain injury: relationship with hypoperfusion challenged. J Trauma. 2010;69:1410-1414.
14. Perel P, Roberts I, Shakur H, Thinkhamrop B, Phuenpathom N, Yutthakasemsunt S. Haemostatic drugs for traumatic brain injury. Cochrane Database Syst Rev. 2010:CD007877.
15. Hauser CJ, Boffard K, Dutton R, et al. Results of the CONTROL trial: efficacy and safety of recombinant activated Factor VII in the management of refractory traumatic hemorrhage. J Trauma. 2010; 69:489-500.
16. Johansson PI. Goal-directed hemostatic resuscitation for massively bleeding patients: the Copenhagen concept. Transfus Apher Sci. 2010; 43:401-405.
17. Schochl H, Nienaber U, Hofer G, et al. Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM)-guided administration of fibrinogen concentrate and prothrombin complex concentrate. Crit Care. 2010;14:R55.
18. Schochl H, Forster L, Woidke R, Solomon C, Voelckel W. Use of rotation thromboelastometry (ROTEM) to achieve successful treatment of polytrauma with fibrinogen concentrate and prothrombin complex concentrate. Anaesthesia. 2010;65:199-203.
19. Nylund CM, Borgman MA, Holcomb JB, Jenkins D, Spinella PC. Thromboelastography to direct the administration of recombinant activated factor VII in a child with traumatic injury requiring massive transfusion. Pediatr Crit Care Med. 2009;10:e22-e26.
20. Kitchen DP, Kitchen S, Jennings I, Woods T, Walker I. Quality assurance and quality control of thrombelastography and rotational thromboelastometry: the UK NEQAS for blood coagulation experience. Semin Thromb Hemost. 2010;36:757-763.