Proteins from Erwinia asparaginase Erwinase® and E. coli asparaginase 2 MEDAC® for treatment of human leukemia, show a multitude of modifications for which the consequences are completely unclear

Electrophoresis

Volumn 32, Issue 14, 2011, Pages 1824-1828

  Bae, Narkhyun ^a   Pollak, Arnold ^a   Lubec, Gert ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Adverse effects; Asparaginases; Leukemia; Therapy

Indexed keywords

AMINO ACIDS; DISEASES; DRUG PRODUCTS; ELECTROPHORESIS; ESCHERICHIA COLI; MOLECULAR BIOLOGY; PRODUCT DESIGN; PROTEINS;

ADVERSE EFFECT; ASPARAGINASE; E. COLI; ERWINIA; L ASPARAGINES; L-ASPARAGINASE; LEUKEMIA; MEDICAL PRODUCTS; PROTEIN MODIFICATIONS; THERAPY;

MASS SPECTROMETRY;

ASPARAGINASE; MEDAC; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; AMINO ACID SEQUENCE; ARTICLE; BIOCHEMISTRY; DRUG DESIGN; ELECTROSPRAY MASS SPECTROMETRY; ESCHERICHIA COLI; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOCHEMISTRY; MASS SPECTROMETRY; PECTOBACTERIUM CHRYSANTHEMI; PHYSICAL CHEMISTRY; PROTEIN MODIFICATION; PROTEIN PROCESSING; PROTEOMICS; TANDEM MASS SPECTROMETRY; TWO DIMENSIONAL ELECTROPHORESIS;

EID: 79960404170     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.201100117     Document Type: Article

References (21)

1. Kotzia, G. A., Labrou, N. E., J. Biotechnol. 2007, 127, 657-669.
2. Keating, M. J., Holmes, R., Lerner, S., Ho, D. H., Leuk. Lymphoma 1993, 10, 153-157.
3. Duval, M., Suciu, S., Ferster, A., Rialland, X., Nelken, B., Lutz, P., Benoit, Y., Robert, A., Manel, A. M., Vilmer, E., Otten, J., Philippe, N., Blood 2002, 99, 2734-2739.
4. Appel, I. M., Hop, W. C., Pieters, R., Blood Coagul. Fibrinolysis 2006, 17, 139-146.
5. Carlsson, H., Stockelberg, D., Tengborn, L., Braide, I., Carneskog, J., Kutti, J., Eur. J. Haematol. 1995, 55, 289-293.
6. Moola, Z. B., Scawen, M. D., Atkinson, T., Nicholls, D. J., Biochem. J. 1994, 302, 921-927.
7. Labrou, N. E., Papageorgiou, A. C., Avramis, V. I., Curr. Med. Chem. 2010, 17, 2183-2195.
8. Chen, W. Q., Siegel, N., Li, L., Pollak, A., Hengstschlager, M., Lubec, G., J. Proteome Res. 2009, 8, 5285-5295.
9. Kang, S. U., Fuchs, K., Sieghart, W., Pollak, A., Csaszar, E., Lubec, G., Nat. Protoc. 2009, 4, 1093-1102.
10. Adams, G. D., Ramsay, J. R., J. Pharm. Sci. 1996, 85, 1301-1305.
11. Benbough, J. E., Wiblin, C. N., Rafter, T. N., Lee, J., Biochem. Pharmacol. 1979, 28, 833-839.
12. Fernandes, A. I., Gregoriadis, G., Biochim. Biophys. Acta 1997, 1341, 26-34.
13. Wileman, T. E., Foster, R. L., Elliott, P. N., J. Pharm. Pharmacol. 1986, 38, 264-271.
14. Aghaiypour, K., Wlodawer, A., Lubkowski, J., Biochemistry 2001, 40, 5655-5664.
15. Lubkowski, J., Dauter, M., Aghaiypour, K., Wlodawer, A., Dauter, Z., Acta Crystallogr. D Biol. Crystallogr. 2003, 59, 84-92.
16. Haebel, S., Albrecht, T., Sparbier, K., Walden, P., Korner, R., Steup, M., Electrophoresis 1998, 19, 679-686.
17. Chao, X., Muff, T. J., Park, S. Y., Zhang, S., Pollard, A. M., Ordal, G. W., Bilwes, A. M., Crane, B. R., Cell 2006, 124, 561-571.
18. Chen, W. Q., Priewalder, H., John, J. P., Lubec, G., Proteomics 2010, 10, 369-379.
19. Blazek, R., Benbough, J. E., Biochim. Biophys. Acta 1981, 677, 220-224.
20. Avramis, V. I., Panosyan, E. H., Clin. Pharmacokinet. 2005, 44, 367-393.
21. Albertsen, B. K., Schroder, H., Ingerslev, J., Jakobsen, P., Avramis, V. I., Müller, H. J., Carlsen, N. T., Schmiegelow, K., Br. J. Haematol. 2001, 115, 983-990.