Infection of hamsters with the UK clostridium difficile ribotype 027 outbreak strain R20291

Journal of Medical Microbiology

Volumn 60, Issue 8, 2011, Pages 1174-1180

  Buckley, Anthony M ^a   Spencer, Janice ^a   Candlish, Denise ^a   Irvine, June J ^a   Douce, Gillian R ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL TOXIN; CLINDAMYCIN PHOSPHATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL SPORE; BACTERIAL STRAIN; CECUM; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE INFECTION; COLON; CONTROLLED STUDY; FEMALE; HAMSTER; IN VIVO STUDY; LEUKOCYTE; MALE; MICROVILLUS; NONHUMAN; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TELEMETRY; UNITED KINGDOM;

ANIMALS; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; CRICETINAE; DISEASE OUTBREAKS; FEMALE; GREAT BRITAIN; HUMANS; KINETICS; MICROSCOPY, ELECTRON, SCANNING; RIBOTYPING;

EID: 79960403385     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.028514-0     Document Type: Article

References (19)

1. Bartlett, J. G., Onderdonk, A. B., Cisneros, R. L. & Kasper, D. L. (1977). Clindamycin-associated colitis due to a toxin-producing species of Clostridium in hamsters. J Infect Dis 136, 701-705.
2. Carter, G. P., Purdy, D., Williams, P. & Minton, N. P. (2005). Quorum sensing in Clostridium difficile: analysis of a LuxS-type signaling system. J Med Microbiol 54, 119-127.
3. Cartman, S. T., Heap, J. T., Kuehne, S. A., Cockayne, A. & Minton, N. P. (2010). The emergence of 'hypervirulence' in Clostridium difficile. Int J Med Microbiol 300, 387-395.
4. Geric, B., Carman, R. J., Rupnik, M., Genheimer, C. W., Sambol, S. P., Lyerly, D. M., Gerding, D. N. & Johnson, S. (2006). Binary toxinproducing, large clostridial toxin-negative Clostridium difficile strains are enterotoxic but do not cause disease in hamsters. J Infect Dis 193, 1143-1150.
5. Goulding, D., Thompson, H., Emerson, J., Fairweather, N. F., Dougan, G. & Douce, G. R. (2009). Distinctive profiles of infection and pathology in hamsters infected with Clostridium difficile strains 630 and B1. Infect Immun 77, 5478-5485.
6. HC (2006). Investigation into Outbreaks of Clostridium difficile at Stoke Mandeville Hospital, Buckinghamshire Hospitals NHS Trust, http://www.cqc.org.uk/_db/_documents/Stoke_Mandeville.pdf, ISBN: 1-84562-103-4. London: Healthcare Commission.
7. Larson, H. E. & Borriello, S. P. (1990). Quantitative study of antibiotic-induced susceptibility to Clostridium difficile enterocecitis in hamsters. Antimicrob Agents Chemother 34, 1348-1353.
8. Lawley, T. D., Croucher, N. J., Yu, L., Clare, S., Sebaihia, M., Goulding, D., Pickard, D. J., Parkhill, J., Choudhary, J. & Dougan, G. (2009). Proteomic and genomic characterization of highly infectious Clostridium difficile 630 spores. J Bacteriol 191, 5377-5386.
9. Marsh, J. W., O'Leary, M. M., Shutt, K. A., Pasculle, A. W., Johnson, S., Gerding, D. N., Muto, C. A. & Harrison, L. H. (2006). Multilocus variable-number tandem-repeat analysis for investigation of Clostridium difficile transmission in hospitals. J Clin Microbiol 44, 2558-2566.
10. Razaq, N., Sambol, S., Nagaro, K., Zukowski, W., Cheknis, A., Johnson, S. & Gerding, D. N. (2007). Infection of hamsters with historical and epidemic BI types of Clostridium difficile. J Infect Dis 196, 1813-1819.
11. Rolfe, R. D. & Song, W. (1993). Purification of a functional receptor for Clostridium difficile toxin A from intestinal brush border membranes of infant hamsters. Clin Infect Dis 16 (Suppl. 4), S219-S227.
12. Rupnik, M., Avesani, V., Janc, M., Von Eichel-Streiber, C. & Delme ́ e, M. (1998). A novel toxinotyping scheme and correlation of toxinotypes with serogroups of Clostridium difficile isolates. J Clin Microbiol 36, 2240-2247.
13. Sambol, S. P., Tang, J. K., Merrigan, M. M., Johnson, S. & Gerding, D. N. (2001). Infection of hamsters with epidemiologically important strains of Clostridium difficile. J Infect Dis 183, 1760-1766.
14. Schwan, C., Stecher, B., Tzivelekidis, T., Van Ham, M., Rohde, M., Hardt, W. D., Wehland, J. & Aktories, K. (2009). Clostridium difficile toxin CDT induces formation of microtubule-based protrusions and increases adherence of bacteria. PLoS Pathog 5, e1000626.
15. Stabler, R. A., He, M., Dawson, L., Martin, M., Valiente, E., Corton, C., Lawley, T. D., Sebaihia, M., Quail, M. A. & other authors (2009). Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium. Genome Biol 10, R102.
16. Stubbe, H., Berdoz, J., Kraehenbuhl, J. P. & Corthe ́ sy, B. (2000). Polymeric IgA is superior to monomeric IgA and IgG carrying the same variable domain in preventing Clostridium difficile toxin A damaging of T84 monolayers. J Immunol 164, 1952-1960.
17. Underwood, S., Guan, S., Vijayasubhash, V., Baines, S. D., Graham, L., Lewis, R. J., Wilcox, M. H. & Stephenson, K. (2009). Characterization of the sporulation initiation pathway of Clostridium difficile and its role in toxin production. J Bacteriol 191, 7296-7305.
18. Warny, M., Pepin, J., Fang, A., Killgore, G., Thompson, A., Brazier, J., Frost, E. & McDonald, L. C. (2005). Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe. Lancet 366, 1079-1084.
19. Wilcox, M. H., Cunniffe, J. G., Trundle, C. & Redpath, C. (1996). Financial burden of hospital-acquired Clostridium difficile infection. J Hosp Infect 34, 23-30.