Correlation of optical coherence tomography with clinical and histopathological findings in experimental autoimmune uveoretinitis

Experimental Eye Research

Volumn 93, Issue 1, 2011, Pages 82-90

  Gadjanski, Ivana ^a,b,c   Williams, Sarah K ^d   Hein, Katharina ^a   Sättler, Muriel B ^a   Bähr, Mathias ^a   Diem, Ricarda ^d  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b State University of Novi Pazar   (Serbia)

^c Research and Development Center for Bioengineering   (Serbia)

^d SAARLAND UNIVERSITY   (Germany)

Author keywords

Experimental autoimmune uveoretinitis; Histopathology; In vivo imaging; Optical coherence tomography; Rats

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE COURSE; EX VIVO STUDY; FEMALE; HISTOPATHOLOGY; IMMUNIZATION; IN VIVO STUDY; MONITORING; NON INVASIVE PROCEDURE; NONHUMAN; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; RAT; SCORING SYSTEM; SENSITIVITY ANALYSIS; STAGING; UVEORETINITIS; VISUAL SYSTEM PARAMETERS;

ANIMALS; AUTOIMMUNE DISEASES; DISEASE MODELS, ANIMAL; EYE PROTEINS; FEMALE; RATS; RATS, INBRED BN; RETINA; RETINITIS; RETINOL-BINDING PROTEINS; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, OPTICAL COHERENCE; UVEITIS;

EID: 79960381616     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2011.04.012     Document Type: Article

References (35)

1. Adamus G., Chan C.C. Experimental autoimmune uveitides: multiple antigens, diverse diseases. Int. Rev. Immunol. 2002, 21:209-229.
2. Agarwal R.K., Caspi R.R. Rodent models of experimental autoimmune uveitis. Methods Mol. Med. 2004, 102:395-419.
3. Agarwal R.K., Sun S.H., Su S.B., et al. Pertussis toxin alters the innate and the adaptive immune responses in a pertussis-dependent model of autoimmunity. J. Neuroimmunol 2002, 129:133-140.
4. Boretius S., Gadjanski I., Demmer I., et al. MRI of optic neuritis in a rat model. Neuroimage 2008, 41:323-334.
5. Caspi R.R., Roberge F.G., McAllister C.G., et al. T cell lines mediating experimental autoimmune uveoretinitis (EAU) in the rat. J. Immunol. 1986, 136:928-933.
6. Caspi R.R., Silver P.B., Chan C.C., et al. Genetic susceptibility to experimental autoimmune uveoretinitis in the rat is associated with an elevated Th1 response. J. Immunol. 1996, 157:2668-2675.
7. Caspi R.R. Experimental autoimmune uveoretinitis in the rat and mouse. Curr. Protoc. Immunol. 2003, 15. 15.6.
8. Cebulla C.M., Ruggeri M., Murray T.G., et al. Spectral domain optical coherence tomography in a murine retinal detachment model. Exp. Eye Res. 2010, 90:521-527.
9. Chan C.C., Caspi RR., Ni M., et al. Pathology of experimental autoimmune uveoretinitis in mice. J. Autoimmun. 1990, 3:247-255.
10. Costello F., Coupland S., Hodge W., et al. Quantifying axonal loss after optic neuritis with optical coherence tomography. Ann. Neurol. 2006, 59:963-969.
11. Diem R., Hobom M., Maier K., et al. Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway. J. Neurosci. 2003, 23:6993-7000.
12. Diem R., Demmer I., Boretius S., et al. Autoimmune optic neuritis in the common marmoset monkey: comparison of visual evoked potentials with MRI and histopathology. Invest. Ophthalmol. Vis. Sci. 2008, 49:3707-3714.
13. Donoso L.A., Merryman C.F., Sery T., et al. Human interstitial retinoid binding protein. A potent uveitopathogenic agent for the induction of experimental autoimmune uveitis. J. Immunol. 1989, 143:79-83.
14. Drexler W., Morgner U., Ghanta R.K., et al. Ultrahigh-resolution ophthalmic optical coherence tomography. Nat. Med. 2001, 7:502-507.
15. Drexler W., Fujimoto J.G. State-of-the-art retinal optical coherence tomography. Prog. Retin. Eye Res. 2008, 27:45-88.
16. Fischer M.D., Huber G., Beck S.C., et al. Noninvasive, in vivo assessment of mouse retinal structure using optical coherence tomography. PLoS One 2009, 4:e7507.
17. Fujimoto J.G., Pitris C., Boppart S.A., Brezinski M.E. Optical coherence tomography: an emerging technology for biomedical imaging and optical biopsy. Neoplasia 2000, 2:9-25.
18. Fujimoto J.G. Optical coherence tomography for ultrahigh resolution in vivo imaging. Nat. Biotechnol. 2003, 21:1361-1367.
19. Gadjanski I., Boretius S., Williams S.K., et al. Role of n-type voltage-dependent calcium channels in autoimmune optic neuritis. Ann. Neurol. 2009, 66:81-93.
20. Grieve K., Pâques M., Dubois A., et al. Ocular tissue imaging using ultrahigh-resolution, full-field optical coherence tomography. Invest. Ophthalmol. Vis. Sci. 2004, 45:4126-4131.
21. Hobom M., Storch M.K., Weissert R., et al. Mechanisms and time course of neuronal degeneration in experimental autoimmune encephalomyelitis. Brain Pathol. 2004, 14:148-157.
22. Huber G., Beck S.C., Grimm C., et al. Spectral domain optical coherence tomography in mouse models of retinal degeneration. Invest. Ophthalmol. Vis. Sci. 2009, 50:5888-5895.
23. Hughes A. A schematic eye for the rat. Vision Res. 1979, 19:569-588.
24. Kaur P., Bennett J.L. Optic neuritis and the neuro-ophthalmology of multiple sclerosis. Int. Rev. Neurobiol. 2007, 79:633-663.
25. Kawaguchi I., Higashide T., Ohkubo S., et al. In vivo imaging and quantitative evaluation of the rat retinal nerve fiber layer using scanning laser ophthalmoscopy. Invest. Ophthalmol. Vis. Sci. 2006, 47:2911-2916.
26. Kocaoglu O.P., Uhlhorn S.R., Hernandez E., et al. Simultaneous fundus imaging and optical coherence tomography of the mouse retina. Invest. Ophthalmol. Vis. Sci. 2007, 48:1283-1289.
27. Li Q., Timmers A.M., Hunter K., et al. Noninvasive imaging by optical coherence tomography to monitor retinal degeneration in the mouse. Invest. Ophthalmol. Vis. Sci. 2001, 42:2981-2989.
28. Maca S.M., Scharitzer M., Barisani-Asenbauer T. Uveitis and neurologic diseases: an often overlooked relationship. Wien. Klin. Wochenschr 2006, 118:273-279.
29. Meyer R., Weissert R., Diem R., et al. Acute neuronal apoptosis in a rat model of multiple sclerosis. J. Neurosci. 2001, 21:6214-6220.
30. Nagata A., Higashide T., Ohkubo S., et al. In vivo quantitative evaluation of the rat retinal nerve fiber layer with optical coherence tomography. Invest. Ophthalmol. Vis. Sci. 2009, 50:2809-2815.
31. Ruggeri M., Wehbe H., Jiao S., et al. In vivo three-dimensional high-resolution imaging of rodent retina with spectral-domain optical coherence tomography. Invest. Ophthalmol. Vis. Sci. 2007, 48:1808-1814.
32. Sakata L.M., Deleon-Ortega J., Sakata V., et al. Optical coherence tomography of the retina and optic nerve - a review. Clin. Exp. Ophthalmol. 2009, 37:90-99.
33. Seiler M.J., Rao B., Aramant R.B., et al. Three-dimensional optical coherence tomography imaging of retinal sheet implants in live rats. J. Neurosci. Methods 2010, 188:250-257.
34. Srinivasan V.J., Ko T.H., Wojtkowski M., et al. Noninvasive volumetric imaging and morphometry of the rodent retina with high-speed, ultrahigh-resolution optical coherence tomography. Invest. Ophthalmol. Vis. Sci. 2006, 47:5522-5528.
35. Trip S.A., Schlottmann P.G., Jones S.J., et al. Optic nerve atrophy and retinal nerve fibre layer thinning following optic neuritis: evidence that axonal loss is a substrate of MRI-detected atrophy. Neuroimage 2006, 15:286-293.