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Volumn 2, Issue 1, 2011, Pages 49-54

Searching for an effective, safe and universal anti-HIV vaccine: Finding the answer in just one short peptide

Author keywords

Conserved viral pentapeptides; HIV versus human peptide overlap; Peptide based anti hiv vaccine; Unique viral pentapeptides; Universal anti hiv vaccine

Indexed keywords

GLYCOPROTEIN GP 160; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; PENTAPEPTIDE;

EID: 79960380774     PISSN: 19382030     EISSN: 19382049     Source Type: Journal    
DOI: 10.4161/self.2.1.14762     Document Type: Article
Times cited : (21)

References (46)
  • 1
    • 44649126811 scopus 로고    scopus 로고
    • The hunt for an HIV vaccine: Time to rethink recent failures
    • Boasso A, Shearer GM, Clerici M. The hunt for an HIV vaccine: Time to rethink recent failures. Lancet 2008; 371:1897-8.
    • (2008) Lancet , vol.371 , pp. 1897-1898
    • Boasso, A.1    Shearer, G.M.2    Clerici, M.3
  • 2
    • 44949125587 scopus 로고    scopus 로고
    • HIV vaccine developers battle on, despite high-profile failures
    • Ledford H. HIV vaccine developers battle on, despite high-profile failures. Nat Biotechnol 2008; 26:591-2.
    • (2008) Nat Biotechnol , vol.26 , pp. 591-592
    • Ledford, H.1
  • 3
    • 68149108469 scopus 로고    scopus 로고
    • HIV vaccine development: Lessons from the past, informing the future
    • Bradac J, Dieffenbach CW. HIV vaccine development: Lessons from the past, informing the future. IDrugs 2009; 12:435-9.
    • (2009) IDrugs , vol.12 , pp. 435-439
    • Bradac, J.1    Dieffenbach, C.W.2
  • 4
    • 68349157593 scopus 로고    scopus 로고
    • Roadblocks in HIV research: Five questions
    • Thomas C. Roadblocks in HIV research: Five questions. Nat Med 2009; 15:855-9.
    • (2009) Nat Med , vol.15 , pp. 855-859
    • Thomas, C.1
  • 5
    • 79952787740 scopus 로고    scopus 로고
    • Human immunodeficiency virus-1 vaccine design: Where do we go now?
    • doi:10.1038/icb.2010.118
    • Wijesundara DK, Jackson RJ, Ramshaw IA, Ranasinghe C. Human immunodeficiency virus-1 vaccine design: where do we go now? Immunol Cell Biol 2010; 89:367-374. doi:10.1038/icb.2010.118.
    • (2010) Immunol Cell Biol , vol.89 , pp. 367-374
    • Wijesundara, D.K.1    Jackson, R.J.2    Ramshaw, I.A.3    Ranasinghe, C.4
  • 6
    • 0024492265 scopus 로고
    • Anti-retroviral therapy in HIV-1-infected persons: Concepts and strategies
    • Stingl G. Anti-retroviral therapy in HIV-1-infected persons: Concepts and strategies. Curr Probl Dermatol 1989; 18:250-68.
    • (1989) Curr Probl Dermatol , vol.18 , pp. 250-268
    • Stingl, G.1
  • 7
    • 34748887166 scopus 로고    scopus 로고
    • Variants with different mutation patterns persist in the quasispecies of enfuvirtide-resistant HIV-1 population during and after treatment in vivo
    • Trabaud MA, Cotte L, Labernardière JL, Lebel-Binay S, Icard V, Tardy JC, et al. Variants with different mutation patterns persist in the quasispecies of enfuvirtide-resistant HIV-1 population during and after treatment in vivo. J Acquir Immune Defic Syndr 2007; 46:134-44.
    • (2007) J Acquir Immune Defic Syndr , vol.46 , pp. 134-144
    • Trabaud, M.A.1    Cotte, L.2    Labernardière, J.L.3    Lebel-Binay, S.4    Icard, V.5    Tardy, J.C.6
  • 8
    • 21344434534 scopus 로고    scopus 로고
    • Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies
    • Haynes BF, Fleming J, St. Clair EW, Katinger H, Stiegler G, Kunert R, et al. Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies. Science 2005; 308:1906-8.
    • (2005) Science , vol.308 , pp. 1906-1908
    • Haynes, B.F.1    Fleming, J.2    Clair St., E.W.3    Katinger, H.4    Stiegler, G.5    Kunert, R.6
  • 9
    • 52049098909 scopus 로고    scopus 로고
    • Massive peptide sharing between viral and human proteomes
    • Kanduc D, Stufano A, Lucchese G, Kusalik A. Massive peptide sharing between viral and human proteomes. Peptides 2008; 29:1755-66.
    • (2008) Peptides , vol.29 , pp. 1755-1766
    • Kanduc, D.1    Stufano, A.2    Lucchese, G.3    Kusalik, A.4
  • 10
    • 79960379027 scopus 로고    scopus 로고
    • Pentapeptide overlapping between human immunodeficiency viruses and Homo sapiens proteomes is higher than 90%
    • Kanduc D. Pentapeptide overlapping between human immunodeficiency viruses and Homo sapiens proteomes is higher than 90%. Retrovirology 2009; 6:44.
    • (2009) Retrovirology , vol.6 , pp. 44
    • Kanduc, D.1
  • 11
    • 79960346115 scopus 로고    scopus 로고
    • Charting the peptide crossreactome between HIV-1 and the human proteome
    • Lucchese G, Stufano A, Calabro' M, Kanduc D. Charting the peptide crossreactome between HIV-1 and the human proteome. Front Biosci 2011; E3: 1385-1400.
    • (2011) Front Biosci , vol.E3 , pp. 1385-1400
    • Lucchese, G.1    Stufano, A.2    Calabro', M.3    Kanduc, D.4
  • 12
    • 0025183723 scopus 로고
    • CD4 is retained in the endoplasmic reticulum by the human immunodeficiency virus type 1 glycoprotein precursor
    • Crise B, Buonocore L, Rose JK. CD4 is retained in the endoplasmic reticulum by the human immunodeficiency virus type 1 glycoprotein precursor. J Virol 1990; 64:5585-93.
    • (1990) J Virol , vol.64 , pp. 5585-5593
    • Crise, B.1    Buonocore, L.2    Rose, J.K.3
  • 13
    • 0035873475 scopus 로고    scopus 로고
    • Secretory IgA specific for a conserved epitope on gp41 envelope glycoprotein inhibits epithelial transcytosis of HIV-1
    • Alfsen A, Iniguez P, Bouguyon E, Bomsel M. Secretory IgA specific for a conserved epitope on gp41 envelope glycoprotein inhibits epithelial transcytosis of HIV-1. J Immunol 2001; 166:6257-65.
    • (2001) J Immunol , vol.166 , pp. 6257-6265
    • Alfsen, A.1    Iniguez, P.2    Bouguyon, E.3    Bomsel, M.4
  • 14
    • 0028047578 scopus 로고
    • Genomic cloning and complete sequence analysis of a highly divergent African human immunodeficiency virus isolate
    • Vanden Haesevelde M, Decourt JL, De Leys RJ, Vanderborght B, van der Groen G, van Heuverswijn H, et al. Genomic cloning and complete sequence analysis of a highly divergent African human immunodeficiency virus isolate. J Virol 1994; 68:1586-96.
    • (1994) J Virol , vol.68 , pp. 1586-1596
    • Vanden, H.M.1    Decourt, J.L.2    de Leys, R.J.3    Vanderborght, B.4    van der Groen, G.5    van Heuverswijn, H.6
  • 15
    • 0036179349 scopus 로고    scopus 로고
    • Identification of a new circulating recombinant form of HIV type 1, CRF11-cpx, involving subtypes A, G, J and CRF01-AE, in Central Africa
    • Montavon C, Vergne L, Bourgeois A, Mpoudi-Ngole E, Malonga-Mouellet G, Butel C, et al. Identification of a new circulating recombinant form of HIV type 1, CRF11-cpx, involving subtypes A, G, J and CRF01-AE, in Central Africa. AIDS Res Hum Retroviruses 2002; 18:231-6.
    • (2002) AIDS Res Hum Retroviruses , vol.18 , pp. 231-236
    • Montavon, C.1    Vergne, L.2    Bourgeois, A.3    Mpoudi-Ngole, E.4    Malonga-Mouellet, G.5    Butel, C.6
  • 16
    • 85047689691 scopus 로고    scopus 로고
    • Biological and genetic characteristics of HIV infections in Cameroon reveals dual group M and O infections and a correlation between SI-inducing phenotype of the predominant CRF02_AG variant and disease stage
    • Vergne L, Bourgeois A, Mpoudi-Ngole E, Mougnutou R, Mbuagbaw J, Liegeois F, et al. Biological and genetic characteristics of HIV infections in Cameroon reveals dual group M and O infections and a correlation between SI-inducing phenotype of the predominant CRF02_AG variant and disease stage. Virology 2003; 310:254-66.
    • (2003) Virology , vol.310 , pp. 254-266
    • Vergne, L.1    Bourgeois, A.2    Mpoudi-Ngole, E.3    Mougnutou, R.4    Mbuagbaw, J.5    Liegeois, F.6
  • 18
    • 36448961979 scopus 로고    scopus 로고
    • Peptidology: Short amino acid modules in cell biology and immunology
    • Lucchese G, Stufano A, Trost B, Kusalik A, Kanduc D. Peptidology: short amino acid modules in cell biology and immunology. Amino Acids 2007; 33:703-7.
    • (2007) Amino Acids , vol.33 , pp. 703-707
    • Lucchese, G.1    Stufano, A.2    Trost, B.3    Kusalik, A.4    Kanduc, D.5
  • 19
    • 79960371985 scopus 로고
    • On the serological specificity of peptides
    • Landsteiner K, van der Scheer J. On the serological specificity of peptides. III. J Exp Med 1939; 69:705-19.
    • (1939) III. J Exp Med , vol.69 , pp. 705-719
    • Landsteiner, K.1    van der Scheer, J.2
  • 20
    • 0023655164 scopus 로고
    • Amonoclonal antibody to the phosphorylated form of phenylalanine hydroxylase: Definition of the phosphopeptide epitope
    • Smith SC, McAdam WJ, Kemp BE, Morgan FJ, Cotton RG. A monoclonal antibody to the phosphorylated form of phenylalanine hydroxylase: Definition of the phosphopeptide epitope. Biochem J 1987; 244:625-31.
    • (1987) Biochem J , vol.244 , pp. 625-631
    • Smith, S.C.1    McAdam, W.J.2    Kemp, B.E.3    Morgan, F.J.4    Cotton, R.G.5
  • 21
    • 0024427692 scopus 로고
    • Conserved lipoprotein H.8 of pathogenic Neisseria consists entirely of pentapeptide repeats
    • Woods JP, Spinola SM, Strobel SM, Cannon JG. Conserved lipoprotein H.8 of pathogenic Neisseria consists entirely of pentapeptide repeats. Mol Microbiol 1989; 3:43-8.
    • (1989) Mol Microbiol , vol.3 , pp. 43-48
    • Woods, J.P.1    Spinola, S.M.2    Strobel, S.M.3    Cannon, J.G.4
  • 22
    • 0024537272 scopus 로고
    • A pentapeptide as minimal antigenic determinant for MHC class I-restricted T lymphocytes
    • Reddehase MJ, Rothbard JB, Koszinowski UH. A pentapeptide as minimal antigenic determinant for MHC class I-restricted T lymphocytes. Nature 1989; 337:651-3.
    • (1989) Nature , vol.337 , pp. 651-653
    • Reddehase, M.J.1    Rothbard, J.B.2    Koszinowski, U.H.3
  • 23
    • 0026650559 scopus 로고
    • Amino acids and peptides. XXXIII. Synthesis of N-terminal epitope peptides of mammalian metallothioneins (MTs)
    • Okada Y, Nakayama S, Iguchi S, Kikuchi Y, Irie M, Sawada J, et al. Amino acids and peptides. XXXIII. Synthesis of N-terminal epitope peptides of mammalian metallothioneins (MTs). Chem Pharm Bull 1992; 40:1029-32.
    • (1992) Chem Pharm Bull , vol.40 , pp. 1029-1032
    • Okada, Y.1    Nakayama, S.2    Iguchi, S.3    Kikuchi, Y.4    Irie, M.5    Sawada, J.6
  • 24
    • 0026783871 scopus 로고
    • Biologically selected recombinants between feline leukemia virus (FeLV) subgroup A and an endogenous FeLV element
    • Sheets RL, Pandey R, Klement V, Grant CK, Roy-Burman P. Biologically selected recombinants between feline leukemia virus (FeLV) subgroup A and an endogenous FeLV element. Virology 1992; 190:849-55.
    • (1992) Virology , vol.190 , pp. 849-855
    • Sheets, R.L.1    Pandey, R.2    Klement, V.3    Grant, C.K.4    Roy-Burman, P.5
  • 25
    • 0027388956 scopus 로고
    • High-resolution epitope mapping and fine antigenic characterization of the main immunogenic region of the acetylcholine receptor: Improving the binding activity of synthetic analogues of the region
    • Papadouli I, Sakarellos C, Tzartos SJ. High-resolution epitope mapping and fine antigenic characterization of the main immunogenic region of the acetylcholine receptor: Improving the binding activity of synthetic analogues of the region. Eur J Biochem 1993; 211:227-34.
    • (1993) Eur J Biochem , vol.211 , pp. 227-234
    • Papadouli, I.1    Sakarellos, C.2    Tzartos, S.J.3
  • 27
    • 6344222970 scopus 로고    scopus 로고
    • Computational peptide dissection of Melan-a/MART-1 oncoprotein antigenicity
    • Tiwari R, Geliebter J, Lucchese A, Mittelman A, Kanduc D. Computational peptide dissection of Melan-a/MART-1 oncoprotein antigenicity. Peptides 2004; 25:1865-71.
    • (2004) Peptides , vol.25 , pp. 1865-1871
    • Tiwari, R.1    Geliebter, J.2    Lucchese, A.3    Mittelman, A.4    Kanduc, D.5
  • 28
    • 33947732849 scopus 로고    scopus 로고
    • Non-redundant peptidomes from DAPs: Towards "the vaccine"?
    • Kanduc D, Lucchese A, Mittelman A. Non-redundant peptidomes from DAPs: Towards "the vaccine"? Autoimmun Rev 2007; 6:290-4.
    • (2007) Autoimmun Rev , vol.6 , pp. 290-294
    • Kanduc, D.1    Lucchese, A.2    Mittelman, A.3
  • 30
    • 59249102885 scopus 로고    scopus 로고
    • Proteome-based epitopic peptide scanning along PSA
    • Stufano A, Kanduc D. Proteome-based epitopic peptide scanning along PSA. Exp Mol Pathol 2009; 86:36-40.
    • (2009) Exp Mol Pathol , vol.86 , pp. 36-40
    • Stufano, A.1    Kanduc, D.2
  • 31
    • 77954553347 scopus 로고    scopus 로고
    • Proposing lowsimilarity peptide vaccines against Mycobacterium tuberculosis
    • Lucchese G, Stufano A, Kanduc D. Proposing lowsimilarity peptide vaccines against Mycobacterium tuberculosis. J Biomed Biotechnol 2010; 832-341.
    • (2010) J Biomed Biotechnol , pp. 832-341
    • Lucchese, G.1    Stufano, A.2    Kanduc, D.3
  • 32
    • 58149356417 scopus 로고    scopus 로고
    • Immunogenicity in peptide-immunotherapy: From self/nonself to similar/dissimilar sequences
    • Kanduc D. Immunogenicity in peptide-immunotherapy: From self/nonself to similar/dissimilar sequences. Adv Exp Med Biol 2008; 640:198-207.
    • (2008) Adv Exp Med Biol , vol.640 , pp. 198-207
    • Kanduc, D.1
  • 33
    • 39749095051 scopus 로고    scopus 로고
    • Correlating low-similarity peptide sequences and allergenic epitopes
    • Kanduc D. Correlating low-similarity peptide sequences and allergenic epitopes. Curr Pharm Des 2008; 14:289-95.
    • (2008) Curr Pharm Des , vol.14 , pp. 289-295
    • Kanduc, D.1
  • 35
    • 70350559569 scopus 로고    scopus 로고
    • Self-nonself" peptides in the design of vaccines
    • Kanduc D. ''Self-nonself" peptides in the design of vaccines. Curr Pharm Des 2009; 15:3283-9.
    • (2009) Curr Pharm Des , vol.15 , pp. 3283-3289
    • Kanduc, D.1
  • 36
    • 77951257522 scopus 로고    scopus 로고
    • Protein information content resides in rare peptide segments
    • Kanduc D. Protein information content resides in rare peptide segments. Peptides 2010; 31:983-8.
    • (2010) Peptides , vol.31 , pp. 983-988
    • Kanduc, D.1
  • 37
    • 78049304049 scopus 로고    scopus 로고
    • The self/nonself issue: A confrontation between proteomes
    • Kanduc D. The self/nonself issue: A confrontation between proteomes. SelfNonself 2010; 1:255-8.
    • (2010) SelfNonself , vol.1 , pp. 255-258
    • Kanduc, D.1
  • 38
    • 55849141268 scopus 로고    scopus 로고
    • Viral sequence diversity: Challenges for AIDS vaccine designs
    • McBurney SP, Ross TM. Viral sequence diversity: challenges for AIDS vaccine designs. Expert Rev Vaccines 2008; 7:1405-17.
    • (2008) Expert Rev Vaccines , vol.7 , pp. 1405-1417
    • McBurney, S.P.1    Ross, T.M.2
  • 39
    • 77956325565 scopus 로고    scopus 로고
    • 4E10-resistant HIV-1 isolated from four subjects with rare membrane-proximal external region polymorphisms
    • Nakamura KJ, Gach JS, Jones L, Semrau K, Walter J, Bibollet-Ruche F, et al. 4E10-resistant HIV-1 isolated from four subjects with rare membrane-proximal external region polymorphisms. PLoS One 2010; 5:9786.
    • (2010) PLoS One , vol.5 , pp. 9786
    • Nakamura, K.J.1    Gach, J.S.2    Jones, L.3    Semrau, K.4    Walter, J.5    Bibollet-Ruche, F.6
  • 40
    • 0042127158 scopus 로고    scopus 로고
    • AIDSVAX B/B, AIDSVAX B/E, HIV gp120 vaccine-Genentech, HIV gp120 vaccine AIDSVAX-VaxGen, HIV vaccine AIDSVAX-VaxGen
    • Adis International Ltd., HIV gp120 vaccine-VaxGen: AIDSVAX
    • Adis International Ltd., HIV gp120 vaccine-VaxGen: AIDSVAX, AIDSVAX B/B, AIDSVAX B/E, HIV gp120 vaccine-Genentech, HIV gp120 vaccine AIDSVAX-VaxGen, HIV vaccine AIDSVAX-VaxGen. Drugs R D 2003; 4:249-53.
    • (2003) Drugs R D , vol.4 , pp. 249-253
  • 41
    • 0038664390 scopus 로고    scopus 로고
    • Comparative immunogenicity in rhesus monkeys of DNA plasmid, recombinant vaccinia virus and replication-defective adenovirus vectors expressing a human immunodeficiency virus type 1 gag gene
    • Casimiro DR, Chen L, Fu TM, Evans RK, Caulfield MJ, Davies ME, et al. Comparative immunogenicity in rhesus monkeys of DNA plasmid, recombinant vaccinia virus and replication-defective adenovirus vectors expressing a human immunodeficiency virus type 1 gag gene. J Virol 2003; 77:6305-13.
    • (2003) J Virol , vol.77 , pp. 6305-6313
    • Casimiro, D.R.1    Chen, L.2    Fu, T.M.3    Evans, R.K.4    Caulfield, M.J.5    Davies, M.E.6
  • 42
    • 77955513770 scopus 로고    scopus 로고
    • Overview of STEP and Phambili trial results: Two phase IIb test-of-concept studies investigating the efficacy of MRK adenovirus type 5 gag/pol/nef subtype B HIV vaccine
    • Gray G, Buchbinder S, Duerr A. Overview of STEP and Phambili trial results: two phase IIb test-of-concept studies investigating the efficacy of MRK adenovirus type 5 gag/pol/nef subtype B HIV vaccine. Curr Opin HIV AIDS 2010; 5:357-61.
    • (2010) Curr Opin HIV AIDS , vol.5 , pp. 357-361
    • Gray, G.1    Buchbinder, S.2    Duerr, A.3
  • 44
    • 75849153303 scopus 로고    scopus 로고
    • UniProt consortium: The universal protein resource (UniProt) in 2010
    • UniProt consortium: The universal protein resource (UniProt) in 2010. Nucleic Acids Res 2010; 38:142-8.
    • (2010) Nucleic Acids Res , vol.38 , pp. 142-148
  • 46
    • 0043123123 scopus 로고    scopus 로고
    • Tcoffee@igs: A web server for computing, evaluating and combining multiple sequence alignments
    • Poirot O, O'Toole E, Notredame C. Tcoffee@igs: A web server for computing, evaluating and combining multiple sequence alignments. Nucleic Acids Res 2003; 31:3503-6.
    • (2003) Nucleic Acids Res , vol.31 , pp. 3503-3506
    • Poirot, O.1    O'Toole, E.2    Notredame, C.3


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