HIV vaccine development: Lessons from the past, informing the future

IDrugs

Volumn 12, Issue 7, 2009, Pages 434-439

  Bradac, James ^a   Dieffenbach, Carl W ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

ELISPOT; HIV; HIV vaccine; Neutralizing antibody; Nonhuman primate model; Simian immuno deficiency virus; SIV; T cell vaccine

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; HLA ANTIGEN; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; NEUTRALIZING ANTIBODY; RECOMBINANT VACCINE; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY;

ADENOVIRUS 5; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CLINICAL RESEARCH; CLINICAL TRIAL; DRUG EFFICACY; EFFECTOR CELL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; IMMUNOGENICITY; MEMORY CELL; NONHUMAN; PRIMATE; REVIEW; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS IMMUNITY; VIRUS LOAD; VIRUS NEUTRALIZATION; ANIMAL; BIOSYNTHESIS; DISEASE MODEL; DRUG DEVELOPMENT; DRUG EFFECT; GENETICS; IMMUNOLOGY; METHODOLOGY; TREATMENT FAILURE;

AIDS VACCINES; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CLINICAL TRIALS AS TOPIC; DISEASE MODELS, ANIMAL; DRUG DISCOVERY; HIV ANTIBODIES; HIV INFECTIONS; HIV-1; HUMANS; TREATMENT FAILURE;

EID: 68149108469     PISSN: 13697056     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (5)

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3. Watkins DI, Burton DR, Kallas EG, Moore JP, Koff WC: Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans. Nat Med (2008) 14(6):617-621.
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