A single nucleotide polymorphism in BMP15 is associated with high response to ovarian stimulation

Reproductive BioMedicine Online

Volumn 23, Issue 1, 2011, Pages 97-104

  Hanevik, Hans Ivar ^a   Hilmarsen, Hilde Tveitan ^b   Skjelbred, Camilla Furu ^b   Tanbo, Tom ^c   Kahn, Jarl A ^a  

^a Telemark Hospital   (Norway)

^b TELEMARK HOSPITAL   (Norway)

^c OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

BMP15; FSH; IVF; ovarian response; polymorphisms

Indexed keywords

BONE MORPHOGENETIC PROTEIN 15;

ADULT; ALLELE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; FEMALE; GENETIC ASSOCIATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; OUTCOME ASSESSMENT; OVARY; SINGLE NUCLEOTIDE POLYMORPHISM; STIMULATION;

ADULT; BONE MORPHOGENETIC PROTEIN 15; CASE-CONTROL STUDIES; FEMALE; GENOTYPE; HUMANS; OVARIAN HYPERSTIMULATION SYNDROME; OVULATION INDUCTION; POLYMORPHISM, SINGLE NUCLEOTIDE; RETROSPECTIVE STUDIES;

EID: 79960350461     PISSN: 14726483     EISSN: 14726491     Source Type: Journal    
DOI: 10.1016/j.rbmo.2011.02.015     Document Type: Article

References (35)

1. J. Aaltonen, M.P. Laitinen, and K. Vuojolainen Human growth differentiation factor 9 (GDF-9) and its novel homolog GDF-9B are expressed in oocytes during early folliculogenesis J. Clin. Endocrinol. Metab. 84 1999 2744 2750 (Pubitemid 30642005)
2. R. Abir, A. Ben-Haroush, N. Melamed, C. Felz, H. Krissi, and B. Fisch Expression of bone morphogenetic proteins 4 and 7 and their receptors IA, IB, and II in human ovaries from fetuses and adults Fertil. Steril. 89 2008 1430 1440 (Pubitemid 351688977)
3. S.K. Achrekar, D.N. Modi, S.K. Desai, V.S. Mangoli, R.V. Mangoli, and S.D. Mahale Follicle-stimulating hormone receptor polymorphism (Thr307Ala) is associated with variable ovarian response and ovarian hyperstimulation syndrome in Indian women Fertil. Steril. 91 2009 432 439
4. S. Altmae, K. Haller, and M. Peters Allelic estrogen receptor 1 (ESR1) gene variants predict the outcome of ovarian stimulation in in vitro fertilization Mol. Hum. Reprod. 13 2007 521 526 (Pubitemid 47241905)
5. C. Alviggi, R. Clarizia, and K. Pettersson Suboptimal response to GnRHa long protocol is associated with a common LH polymorphism Reprod. Biomed. Online 18 2009 9 14
6. J.C. Barrett, B. Fry, J. Maller, and M.J. Daly Haploview: analysis and visualization of LD and haplotype maps Bioinformatics 21 2005 263 265 (Pubitemid 40202029)
7. H.M. Behre, R.R. Greb, and A. Mempel Significance of a common single nucleotide polymorphism in exon 10 of the follicle-stimulating hormone (FSH) receptor gene for the ovarian response to FSH: a pharmacogenetic approach to controlled ovarian hyperstimulation Pharmacogenet. Genomics 15 2005 451 456 (Pubitemid 41017593)
8. F.J. Broekmans, J. Kwee, D.J. Hendriks, B.W. Mol, and C.B. Lambalk A systematic review of tests predicting ovarian reserve and IVF outcome Hum. Reprod. Update 12 2006 685 718 (Pubitemid 44605509)
9. C. Daelemans, G. Smits, and V. de Maertelaer Prediction of severity of symptoms in iatrogenic ovarian hyperstimulation syndrome by follicle-stimulating hormone receptor Ser680Asn polymorphism J. Clin. Endocrinol. Metab. 89 2004 6310 6315 (Pubitemid 39628451)
10. F. de Castro, F.J. Moron, and L. Montoro Human controlled ovarian hyperstimulation outcome is a polygenic trait Pharmacogenetics 14 2004 285 293 (Pubitemid 38638915)
11. A. Delvigne Symposium: update on prediction and management of OHSS. Epidemiology of OHSS Reprod. Biomed. Online 19 2009 8 13
12. E. Di Pasquale, P. Beck-Peccoz, and L. Persani Hypergonadotropic ovarian failure associated with an inherited mutation of human bone morphogenetic protein-15 (BMP15) gene Am. J. Hum. Genet. 75 2004 106 111 (Pubitemid 38801906)
13. W.D. Dupont, and W.D. Plummer Jr. Power and sample size calculations. A review and computer program Control. Clin. Trials 11 1990 116 128 (Pubitemid 20136185)
14. A. Enskog, M. Henriksson, M. Unander, L. Nilsson, and M. Brannstrom Prospective study of the clinical and laboratory parameters of patients in whom ovarian hyperstimulation syndrome developed during controlled ovarian hyperstimulation for in vitro fertilization Fertil. Steril. 71 1999 808 814 (Pubitemid 29206902)
15. H. Falconer, E. Andersson, A. Aanesen, and G. Fried Follicle-stimulating hormone receptor polymorphisms in a population of infertile women Acta Obstet. Gynecol. Scand. 84 2005 806 811 (Pubitemid 41039907)
16. P. Fedorcsak, P.O. Dale, and R. Storeng Impact of overweight and underweight on assisted reproduction treatment Hum. Reprod. 19 2004 2523 2528 (Pubitemid 39481277)
17. H.I. Hanevik, H.T. Hilmarsen, C.F. Skjelbred, T. Tanbo, and J.A. Kahn Single nucleotide polymorphisms in the anti-Mullerian hormone signalling pathway do not determine high or low response to ovarian stimulation Reprod. Biomed. Online 21 2010 616 623
18. E. Kerkelä, H. Skottman, B. Friden, K. Bjuresten, J. Kere, and O. Hovatta Exclusion of coding-region mutations in luteinizing hormone and follicle-stimulating hormone receptor genes as the cause of ovarian hyperstimulation syndrome Fertil. Steril. 87 2007 603 606 (Pubitemid 46385967)
19. E.R. Klinkert, F.J. Broekmans, C.W. Looman, J.D. Habbema, and E.R. te Velde Expected poor responders on the basis of an antral follicle count do not benefit from a higher starting dose of gonadotrophins in IVF treatment: a randomized controlled trial Hum. Reprod. 20 2005 611 615 (Pubitemid 40425484)
20. T.H. Lee, C.H. Liu, and C.C. Huang Serum anti-Mullerian hormone and estradiol levels as predictors of ovarian hyperstimulation syndrome in assisted reproduction technology cycles Hum. Reprod. 23 2008 160 167
21. S. Margulis, R. Abir, C. Felz, S. Nitke, H. Krissi, and B. Fisch Bone morphogenetic protein 15 expression in human ovaries from fetuses, girls, and women Fertil. Steril. 92 2009 1666 1673
22. R.K. Moore, F. Otsuka, and S. Shimasaki Molecular basis of bone morphogenetic protein-15 signaling in granulosa cells J. Biol. Chem. 278 2003 304 310 (Pubitemid 36043577)
23. F.J. Moron, F. de Castro, and J.L. Royo Bone morphogenetic protein 15 (BMP15) alleles predict over-response to recombinant follicle stimulation hormone and iatrogenic ovarian hyperstimulation syndrome (OHSS) Pharmacogenet. Genomics 16 2006 485 495 (Pubitemid 43922346)
24. F. Otsuka Multiple endocrine regulation by bone morphogenetic protein system Endocr. J. 57 2010 3 14
25. F. Otsuka, S. Yamamoto, G.F. Erickson, and S. Shimasaki Bone morphogenetic protein-15 inhibits follicle-stimulating hormone (FSH) action by suppressing FSH receptor expression J. Biol. Chem. 276 2001 11387 11392 (Pubitemid 38089331)
26. M. Perez Mayorga, J. Gromoll, H.M. Behre, C. Gassner, E. Nieschlag, and M. Simoni Ovarian response to follicle-stimulating hormone (FSH) stimulation depends on the FSH receptor genotype J. Clin. Endocrinol. Metab. 85 2000 3365 3369
27. B. Popovic-Todorovic, A. Loft, A. Lindhard, S. Bangsboll, A.M. Andersson, and A.N. Andersen A prospective study of predictive factors of ovarian response in 'standard' IVF/ICSI patients treated with recombinant FSH. A suggestion for a recombinant FSH dosage normogram Hum. Reprod. 18 2003 781 787 (Pubitemid 36426957)
28. B. Popovic-Todorovic, A. Loft, S. Ziebe, and A.N. Andersen Impact of recombinant FSH dose adjustments on ovarian response in the second treatment cycle with IVF or ICSI in 'standard' patients treated with 150 IU/day during the first cycle Acta Obstet. Gynecol. Scand. 83 2004 842 849 (Pubitemid 39179440)
29. B. Rizk, and M. Aboulghar Classification, pathophysiology and management of ovarian hyperstimulation syndrome P. Brinsden, A textbook of In Vitro Fertilization and Assisted Reproduction: The Bourne Hall guide to clinical and laboratory practice 1999 The Parthenon Publishing Group Lancs./New York 131 155
30. P. Saldeen, K. Kallen, and P. Sundstrom The probability of successful IVF outcome after poor ovarian response Acta Obstet. Gynecol. Scand. 86 2007 457 461 (Pubitemid 46747696)
31. S. Shimasaki, R.K. Moore, F. Otsuka, and G.F. Erickson The bone morphogenetic protein system in mammalian reproduction Endocr. Rev. 25 2004 72 101 (Pubitemid 38292039)
32. M. Simoni, C.B. Tempfer, B. Destenaves, and B.C. Fauser Functional genetic polymorphisms and female reproductive disorders. Part I: polycystic ovary syndrome and ovarian response Hum. Reprod. Update 14 2008 459 484
33. T. Tanbo, E. Kjekshus, and P.O. Dale Intracytoplasmic sperm injection Tidsskr. Nor. Laegeforen. 118 1998 864 869 (Pubitemid 128767577)
34. C.J. Thaler, H. Budiman, H. Ruebsamen, D. Nagel, and P. Lohse Effects of the common 677C>T mutation of the 5, 10-methylenetetrahydrofolate reductase (MTHFR) gene on ovarian responsiveness to recombinant follicle-stimulating hormone Am. J. Reprod. Immunol. 55 2006 251 258 (Pubitemid 43349260)
35. J. van Disseldorp, L. Franke, and M.J.C. Eijkemans Genomic predictors of ovarian response to stimulation for in vitro fertilization J. van Disseldorp, Menopause and Ovarian Reserve: Genetic and Clinical Aspects (Thesis) 2009 University of Utrecht The Netherlands 65 75