메뉴 건너뛰기




Volumn 6, Issue 4, 2011, Pages

The genetic association of variants in CD6, TNFRSF1A and IRF8 to multiple sclerosis: A multicenter case-control study

(44)  Leppä, Virpi a,b   Surakka, Ida a,b   Tienari, Pentti J a   Elovaara, Irina c   Compston, Alastair d   Sawcer, Stephen d   Robertson, Neil e   de Jager, Philip L f,g   Aubin, Cristin g   Hafler, David A g,h   Oturai, Annette Bang i   Søndergaard, Helle Bach i   Sellebjerg, Finn i   Sørensen, Per Soelberg i   Hemmer, Bernhard j   Cepok, Sabine j   Winkelmann, Juliane j,k,l   Wichmann, Heinz Erich l,m   Comabella, Manuel n   Bustamante, Marta F n   more..


Author keywords

[No Author keywords available]

Indexed keywords

CD6 ANTIGEN; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1A; UNCLASSIFIED DRUG; INTERFERON REGULATORY FACTOR; LEUKOCYTE ANTIGEN; T LYMPHOCYTE ANTIGEN; TNFRSF1A PROTEIN, HUMAN; TUMOR NECROSIS FACTOR RECEPTOR 1;

EID: 79960334826     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018813     Document Type: Article
Times cited : (62)

References (32)
  • 1
    • 0015465865 scopus 로고
    • Histocompatibility (HL-A) antigens associated with multiple sclerosis
    • Jersild C, Fog T, (1972) Histocompatibility (HL-A) antigens associated with multiple sclerosis. Acta Neurol Scand Suppl 51: 377.
    • (1972) Acta Neurol Scand Suppl , vol.51 , pp. 377
    • Jersild, C.1    Fog, T.2
  • 2
    • 34548299105 scopus 로고    scopus 로고
    • Risk alleles for multiple sclerosis identified by a genomewide study
    • IMSGC
    • IMSGC (2007) Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med 357: 851-862.
    • (2007) N Engl J Med , vol.357 , pp. 851-862
  • 4
    • 59149093148 scopus 로고    scopus 로고
    • The expanding genetic overlap between multiple sclerosis and type I diabetes
    • IMSGC
    • IMSGC (2009) The expanding genetic overlap between multiple sclerosis and type I diabetes. Genes Immun 10: 11-14.
    • (2009) Genes Immun , vol.10 , pp. 11-14
  • 5
    • 35748981184 scopus 로고    scopus 로고
    • Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
    • Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, et al. (2007) Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet 39: 1329-1337.
    • (2007) Nat Genet , vol.39 , pp. 1329-1337
    • Burton, P.R.1    Clayton, D.G.2    Cardon, L.R.3    Craddock, N.4    Deloukas, P.5
  • 6
    • 76049083598 scopus 로고    scopus 로고
    • Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene
    • Jakkula E, Leppa V, Sulonen AM, Varilo T, Kallio S, et al. (2010) Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene. Am J Hum Genet 86: 285-291.
    • (2010) Am J Hum Genet , vol.86 , pp. 285-291
    • Jakkula, E.1    Leppa, V.2    Sulonen, A.M.3    Varilo, T.4    Kallio, S.5
  • 7
    • 77950544633 scopus 로고    scopus 로고
    • Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci
    • IMSGC
    • IMSGC (2010) Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci. Hum Mol Genet 19: 953-962.
    • (2010) Hum Mol Genet , vol.19 , pp. 953-962
  • 8
    • 67649881102 scopus 로고    scopus 로고
    • Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20
    • ANZgene
    • ANZgene (2009) Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Nat Genet 41: 824-828.
    • (2009) Nat Genet , vol.41 , pp. 824-828
  • 9
    • 77952884985 scopus 로고    scopus 로고
    • Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis
    • Sanna S, Pitzalis M, Zoledziewska M, Zara I, Sidore C, et al. (2010) Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis. Nat Genet 42: 495-497.
    • (2010) Nat Genet , vol.42 , pp. 495-497
    • Sanna, S.1    Pitzalis, M.2    Zoledziewska, M.3    Zara, I.4    Sidore, C.5
  • 10
    • 77954886757 scopus 로고    scopus 로고
    • IL12A, MPHOSPH9/CDK2AP1 and RGS1 are novel multiple sclerosis susceptibility loci
    • IMSGC
    • IMSGC (2010) IL12A, MPHOSPH9/CDK2AP1 and RGS1 are novel multiple sclerosis susceptibility loci. Genes Immun 11: 397-405.
    • (2010) Genes Immun , vol.11 , pp. 397-405
  • 11
    • 67649876123 scopus 로고    scopus 로고
    • Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
    • De Jager PL, Jia X, Wang J, de Bakker PI, Ottoboni L, et al. (2009) Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet 41: 776-782.
    • (2009) Nat Genet , vol.41 , pp. 776-782
    • de Jager, P.L.1    Jia, X.2    Wang, J.3    de Bakker, P.I.4    Ottoboni, L.5
  • 12
    • 49649084390 scopus 로고    scopus 로고
    • Correlation between genetic and geographic structure in Europe
    • Lao O, Lu TT, Nothnagel M, Junge O, Freitag-Wolf S, et al. (2008) Correlation between genetic and geographic structure in Europe. Curr Biol 18: 1241-1248.
    • (2008) Curr Biol , vol.18 , pp. 1241-1248
    • Lao, O.1    Lu, T.T.2    Nothnagel, M.3    Junge, O.4    Freitag-Wolf, S.5
  • 13
    • 65549126774 scopus 로고    scopus 로고
    • Genetic structure of Europeans: a view from the North-East
    • Nelis M, Esko T, Magi R, Zimprich F, Zimprich A, et al. (2009) Genetic structure of Europeans: a view from the North-East. PLoS One 4: e5472.
    • (2009) PLoS One , vol.4
    • Nelis, M.1    Esko, T.2    Magi, R.3    Zimprich, F.4    Zimprich, A.5
  • 15
    • 18144415857 scopus 로고    scopus 로고
    • Integrating case-control and TDT studies
    • Kazeem GR, Farrall M, (2005) Integrating case-control and TDT studies. Ann Hum Genet 69: 329-335.
    • (2005) Ann Hum Genet , vol.69 , pp. 329-335
    • Kazeem, G.R.1    Farrall, M.2
  • 16
    • 65549084289 scopus 로고    scopus 로고
    • Pathway and network-based analysis of genome-wide association studies in multiple sclerosis
    • Baranzini SE, Galwey NW, Wang J, Khankhanian P, Lindberg R, et al. (2009) Pathway and network-based analysis of genome-wide association studies in multiple sclerosis. Hum Mol Genet 18: 2078-2090.
    • (2009) Hum Mol Genet , vol.18 , pp. 2078-2090
    • Baranzini, S.E.1    Galwey, N.W.2    Wang, J.3    Khankhanian, P.4    Lindberg, R.5
  • 17
    • 0030903027 scopus 로고    scopus 로고
    • Human immune disorder arising from mutation of the alpha chain of the interleukin-2 receptor
    • Sharfe N, Dadi HK, Shahar M, Roifman CM, (1997) Human immune disorder arising from mutation of the alpha chain of the interleukin-2 receptor. Proc Natl Acad Sci U S A 94: 3168-3171.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 3168-3171
    • Sharfe, N.1    Dadi, H.K.2    Shahar, M.3    Roifman, C.M.4
  • 18
    • 0031740732 scopus 로고    scopus 로고
    • Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency
    • Puel A, Ziegler SF, Buckley RH, Leonard WJ, (1998) Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency. Nat Genet 20: 394-397.
    • (1998) Nat Genet , vol.20 , pp. 394-397
    • Puel, A.1    Ziegler, S.F.2    Buckley, R.H.3    Leonard, W.J.4
  • 19
    • 33845897463 scopus 로고    scopus 로고
    • Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity
    • Minegishi Y, Saito M, Morio T, Watanabe K, Agematsu K, et al. (2006) Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity. Immunity 25: 745-755.
    • (2006) Immunity , vol.25 , pp. 745-755
    • Minegishi, Y.1    Saito, M.2    Morio, T.3    Watanabe, K.4    Agematsu, K.5
  • 20
    • 34548317417 scopus 로고    scopus 로고
    • Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome
    • Minegishi Y, Saito M, Tsuchiya S, Tsuge I, Takada H, et al. (2007) Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome. Nature 448: 1058-1062.
    • (2007) Nature , vol.448 , pp. 1058-1062
    • Minegishi, Y.1    Saito, M.2    Tsuchiya, S.3    Tsuge, I.4    Takada, H.5
  • 21
    • 58249112158 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor-associated periodic syndrome: toward a molecular understanding of the systemic autoinflammatory diseases
    • Ryan JG, Aksentijevich I, (2009) Tumor necrosis factor receptor-associated periodic syndrome: toward a molecular understanding of the systemic autoinflammatory diseases. Arthritis Rheum 60: 8-11.
    • (2009) Arthritis Rheum , vol.60 , pp. 8-11
    • Ryan, J.G.1    Aksentijevich, I.2
  • 22
    • 34547747790 scopus 로고    scopus 로고
    • Late-onset tumor necrosis factor receptor-associated periodic syndrome in multiple sclerosis patients carrying the TNFRSF1A R92Q mutation
    • Kumpfel T, Hoffmann LA, Rubsamen H, Pollmann W, Feneberg W, et al. (2007) Late-onset tumor necrosis factor receptor-associated periodic syndrome in multiple sclerosis patients carrying the TNFRSF1A R92Q mutation. Arthritis Rheum 56: 2774-2783.
    • (2007) Arthritis Rheum , vol.56 , pp. 2774-2783
    • Kumpfel, T.1    Hoffmann, L.A.2    Rubsamen, H.3    Pollmann, W.4    Feneberg, W.5
  • 23
    • 0041853690 scopus 로고    scopus 로고
    • Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
    • Micheau O, Tschopp J, (2003) Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114: 181-190.
    • (2003) Cell , vol.114 , pp. 181-190
    • Micheau, O.1    Tschopp, J.2
  • 24
    • 0034633542 scopus 로고    scopus 로고
    • Divergent roles for p55 and p75 tumor necrosis factor receptors in the pathogenesis of MOG(35-55)-induced experimental autoimmune encephalomyelitis
    • Suvannavejh GC, Lee HO, Padilla J, Dal Canto MC, Barrett TA, et al. (2000) Divergent roles for p55 and p75 tumor necrosis factor receptors in the pathogenesis of MOG(35-55)-induced experimental autoimmune encephalomyelitis. Cell Immunol 205: 24-33.
    • (2000) Cell Immunol , vol.205 , pp. 24-33
    • Suvannavejh, G.C.1    Lee, H.O.2    Padilla, J.3    Dal Canto, M.C.4    Barrett, T.A.5
  • 25
    • 0029751983 scopus 로고    scopus 로고
    • Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2
    • van Oosten BW, Barkhof F, Truyen L, Boringa JB, Bertelsmann FW, et al. (1996) Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2. Neurology 47: 1531-1534.
    • (1996) Neurology , vol.47 , pp. 1531-1534
    • van Oosten, B.W.1    Barkhof, F.2    Truyen, L.3    Boringa, J.B.4    Bertelsmann, F.W.5
  • 26
    • 0029124057 scopus 로고
    • The membrane-proximal scavenger receptor cysteine-rich domain of CD6 contains the activated leukocyte cell adhesion molecule binding site
    • Whitney GS, Starling GC, Bowen MA, Modrell B, Siadak AW, et al. (1995) The membrane-proximal scavenger receptor cysteine-rich domain of CD6 contains the activated leukocyte cell adhesion molecule binding site. J Biol Chem 270: 18187-18190.
    • (1995) J Biol Chem , vol.270 , pp. 18187-18190
    • Whitney, G.S.1    Starling, G.C.2    Bowen, M.A.3    Modrell, B.4    Siadak, A.W.5
  • 27
    • 0023767124 scopus 로고
    • The human LFA-3 gene is located at the same chromosome band as the gene for its receptor CD2
    • Sewell WA, Palmer RW, Spurr NK, Sheer D, Brown MH, et al. (1988) The human LFA-3 gene is located at the same chromosome band as the gene for its receptor CD2. Immunogenetics 28: 278-282.
    • (1988) Immunogenetics , vol.28 , pp. 278-282
    • Sewell, W.A.1    Palmer, R.W.2    Spurr, N.K.3    Sheer, D.4    Brown, M.H.5
  • 28
    • 0035988234 scopus 로고    scopus 로고
    • CD6: expression during development, apoptosis and selection of human and mouse thymocytes
    • Singer NG, Fox DA, Haqqi TM, Beretta L, Endres JS, et al. (2002) CD6: expression during development, apoptosis and selection of human and mouse thymocytes. Int Immunol 14: 585-597.
    • (2002) Int Immunol , vol.14 , pp. 585-597
    • Singer, N.G.1    Fox, D.A.2    Haqqi, T.M.3    Beretta, L.4    Endres, J.S.5
  • 29
    • 0027464265 scopus 로고
    • Interferon consensus sequence-binding protein, a member of the interferon regulatory factor family, suppresses interferon-induced gene transcription
    • Nelson N, Marks MS, Driggers PH, Ozato K, (1993) Interferon consensus sequence-binding protein, a member of the interferon regulatory factor family, suppresses interferon-induced gene transcription. Mol Cell Biol 13: 588-599.
    • (1993) Mol Cell Biol , vol.13 , pp. 588-599
    • Nelson, N.1    Marks, M.S.2    Driggers, P.H.3    Ozato, K.4
  • 30
    • 0033680746 scopus 로고    scopus 로고
    • ICSBP directs bipotential myeloid progenitor cells to differentiate into mature macrophages
    • Tamura T, Nagamura-Inoue T, Shmeltzer Z, Kuwata T, Ozato K, (2000) ICSBP directs bipotential myeloid progenitor cells to differentiate into mature macrophages. Immunity 13: 155-165.
    • (2000) Immunity , vol.13 , pp. 155-165
    • Tamura, T.1    Nagamura-Inoue, T.2    Shmeltzer, Z.3    Kuwata, T.4    Ozato, K.5
  • 31
    • 16044369709 scopus 로고    scopus 로고
    • Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene
    • Holtschke T, Lohler J, Kanno Y, Fehr T, Giese N, et al. (1996) Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene. Cell 87: 307-317.
    • (1996) Cell , vol.87 , pp. 307-317
    • Holtschke, T.1    Lohler, J.2    Kanno, Y.3    Fehr, T.4    Giese, N.5
  • 32
    • 58149148414 scopus 로고    scopus 로고
    • IRF8 regulates B-cell lineage specification, commitment, and differentiation
    • Wang H, Lee CH, Qi C, Tailor P, Feng J, et al. (2008) IRF8 regulates B-cell lineage specification, commitment, and differentiation. Blood 112: 4028-4038.
    • (2008) Blood , vol.112 , pp. 4028-4038
    • Wang, H.1    Lee, C.H.2    Qi, C.3    Tailor, P.4    Feng, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.