Prioritizing the repair of DNA damage that is encountered by RNA polymerase

Transcription

Volumn 2, Issue 4, 2011, Pages 168-172

  Savery, Nigel ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

DNA damage recognition; DNA repair; Transcription elongation; Transcription coupled repair; UvrA

Indexed keywords

ADENOSINE TRIPHOSPHATE DEPENDENT PROTEINASE; DNA DIRECTED DNA POLYMERASE BETA; GENE PRODUCT; HELICASE; PROTEIN MFD; RNA POLYMERASE; UNCLASSIFIED DRUG; UVRA HELICASE; UVRB HELICASE; UVRC HELICASE; UVRD HELICASE;

ARTICLE; BACTERIUM; CARBOXY TERMINAL SEQUENCE; DNA DAMAGE; DNA REPAIR; DNA TRANSFER; ENZYME ACTIVE SITE; ENZYME ACTIVITY; GENE OVEREXPRESSION; MOLECULAR INTERACTION; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN DNA BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; RNA TRANSLATION; TRANSCRIPTION REGULATION; UPREGULATION;

EID: 79960329985     PISSN: 21541264     EISSN: 21541272     Source Type: Journal    
DOI: 10.4161/trns.2.4.16146     Document Type: Article

References (30)

1. Scicchitano DA, Olesnicky EC, Dimitri A. Transcription and DNA adducts: What happens when the message gets cut off? DNA Repair 2004; 3: 1537-48.
2. Hanawalt PC, Spivak G. Transcription-coupled DNA repair: Two decades of progress and surprises. Nat Rev Mol Cell Biol 2008; 9: 958-70.
3. Mellon I, Hanawalt PC. Induction of the Escherichia coli lactose operon selectively increases repair of its transcribed DNA strand. Nature 1989; 342: 95-8.
4. Savery NJ. The molecular mechanism of transcription-coupled DNA repair. Trends Microbiol 2007; 15: 326-33.
5. Park JS, Marr MT, Roberts JW. E. coli Transcription Repair Coupling Factor (Mfd Protein) rescues arrested complexes by promoting forward translocation. Cell 2002; 109: 757-67.
6. Deaconescu AM, Chambers AL, Smith AJ, Nickels BE, Hochschild A, Savery NJ, et al. Structural basis for bacterial transcription-coupled DNA repair. Cell 2006; 124: 507-20.
7. Smith AJ, Savery NJ. RNA polymerase mutants defective in the initiation of transcription-coupled DNA repair. Nucleic Acids Res 2005; 33: 755-64.
8. Truglio JJ, Croteau DL, Van Houten B, Kisker C. Prokaryotic nucleotide excision repair: The UvrABC system. Chem Rev 2006; 106: 233-52.
9. Selby CP, Sancar A. Molecular mechanism of transcription-repair coupling. Science 1993; 260: 53-8.
10. Westblade LF, Campbell EA, Pukhrambam C, Padovan JC, Nickels BE, Lamour V, et al. Structural basis for the bacterial transcription-repair coupling factor/RNA polymerase interaction. Nucleic Acids Res 2010; 38: 8357-69.
11. Smith AJ, Szczelkun MD, Savery NJ. Controlling the motor activity of a transcription-repair coupling factor: Autoinhibition and the role of RNA polymerase. Nucleic Acids Res 2007; 35: 1802-11.
12. Murphy MN, Gong P, Ralto K, Manelyte L, Savery NJ, Theis K. An N-terminal clamp restrains the motor domains of the bacterial transcription-repair coupling factor Mfd. Nucleic Acids Res 2009; 37: 6042-53.
13. Manelyte L, Kim YIT, Smith AJ, Smith RM, Savery NJ. Regulation and Rate Enhancement during Transcription-Coupled DNA Repair. Molecular Cell 2010; 40: 714-24.
14. Srivastava DB, Darst SA. Derepression of Bacterial Transcription-Repair Coupling Factor Is Associated with a Profound Conformational Change. Journal of Molecular Biology 2011; 406: 275-84.
15. Assenmacher N, Wenig K, Lammens A, Hopfner KP. Structural basis for transcription-coupled repair: The N terminus of Mfd resembles UvrB with degenerate ATPase motifs. J Mol Biol 2006; 355: 675-83.
16. Truglio JJ, Croteau DL, Skorvaga M, DellaVecchia MJ, Theis K, Mandavilli BS, et al. Interactions between UvrA and UvrB: the role of UvrB's domain 2 in nucleotide excision repair. EMBO J 2004; 23: 2498-509.
17. Pakotiprapha D, Liu Y, Verdine GL, Jeruzalmi D. A structural model for the damage-sensing complex in bacterial nucleotide excision repair. J Biol Chem 2009; 284: 12837-44.
18. Caron PR, Grossman L. Involvement of a cryptic ATPase activity of UvrB and its proteolysis product, UvrB* in DNA repair. Nucleic Acids Res 1988; 16: 10891-902.
19. Selby CP, Sancar A. Structure and function of transcription-repair coupling factor. I. Structural domains and binding properties. J Biol Chem 1995; 270: 4882-9.
20. Mu D, Sancar A. Model for XPC-independent transcription-coupled repair of pyrimidine dimers in humans. J Biol Chem 1997; 272: 7570-3.
21. Jaciuk M, Nowak E, Skowronek K, Tanska A, Nowotny M. Structure of UvrA nucleotide excision repair protein in complex with modified DNA. Nat Struct Mol Biol 2011; 18: 191-7.
22. Pakotiprapha D, Inuzuka Y, Bowman BR, Moolenaar GF, Goosen N, Jeruzalmi D, et al. Crystal structure of Bacillus stearothermophilus UvrA provides insight into ATP-modulated dimerization, UvrB interaction and DNA binding. Mol Cell 2008; 29: 122-33.
23. Timmins J, Gordon E, Caria S, Leonard G, Acajjaoui S, Kuo MS, et al. Structural and mutational analyses of Deinococcus radiodurans UvrA2 provide insight into DNA binding and damage recognition by UvrAs. Structure 2009; 17: 547-58.
24. Wagner K, Moolenaar GF, Goosen N. Role of the insertion domain and the zinc-finger motif of Escherichia coli UvrA in damage recognition and ATP hydrolysis. DNA Repair (Amst) 2011; 10: 483-96.
25. Mazon G, Philippin G, Cadet J, Gasparutto D, Fuchs RP. The alkyltransferase-like ybaZ gene product enhances nucleotide excision repair of O(6)-alkylguanine adducts in E. coli. DNA Repair (Amst) 2009; 8: 697-703.
26. Cohen SE, Lewis CA, Mooney RA, Kohanski MA, Collins JJ, Landick R, et al. Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli. Proceedings of the National Academy of Sciences 2010; 107: 15517-22.
27. Crowley DJ, Hanawalt PC. Induction of the SOS Response Increases the Efficiency of Global Nucleotide Excision Repair of Cyclobutane Pyrimidine Dimers, but Not 6-4 Photoproducts, in UV-Irradiated Escherichia coli. J Bacteriol 1998; 180: 3345-52.
28. Selby CP, Sancar A. Structure and function of transcription-repair coupling factor. II. Catalytic properties. J Biol Chem 1995; 270: 4890-5.
29. Orren DK, Selby CP, Hearst JE, Sancar A. Post-incision steps of nucleotide excision repair in Escherichia coli. Disassembly of the UvrBC-DNA complex by helicase II and DNA polymerase I. J Biol Chem 1992; 267: 780-8.
30. Kunala S, Brash DE. Intragenic domains of strand-specific repair in Escherichia coli. J Mol Biol 1995; 246: 264-72.