SugE, a new member of the SMR family of transporters, contributes to antimicrobial resistance in Enterobacter cloacae

Antimicrobial Agents and Chemotherapy

Volumn 55, Issue 8, 2011, Pages 3954-3957

  He, Gui Xin ^a   Zhang, Chu ^a   Crow, Robert R ^b   Thorpe, Conner ^a   Chen, Huizhong ^c   Kumar, Sanath ^b   Tsuchiya, Tomofusa ^d   Varela, Manuel F ^b  

^a UNIVERSITY OF MASSACHUSETTS LOWELL   (United States)

^b EASTERN NEW MEXICO UNIVERSITY   (United States)

^c NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^d OKAYAMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BENZALKONIUM CHLORIDE; CETRIMIDE; CETYLPYRIDINIUM SALT; DODECYL SULFATE SODIUM; ETHIDIUM BROMIDE; TETRAPHENYLPHOSPHONIUM;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; ENTEROBACTER CLOACAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SUGE BACTERIAL GENE;

ANTI-BACTERIAL AGENTS; BASE SEQUENCE; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ENTEROBACTER CLOACAE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE KNOCKOUT TECHNIQUES; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MICROBIAL SENSITIVITY TESTS; MOLECULAR CHAPERONES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; SEQUENCE DELETION;

EID: 79960323776     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00094-11     Document Type: Article

References (21)

1. Abe, S., and E. Davies. 1986. Quantitative analysis of polysomes using a baseline from uncentrifuged blank gradients. Mem. Coll. Agric. 31:187-199.
2. +-coupled multidrug efflux pumps from Vibrio parahaemolyticus. J. Bacteriol. 184:572-576.
3. Corkill, J. E., J. J. Anson, and C. A. Hart. 2005. High prevalence of the plasmid-mediated quinolone resistance determinant qnrA in multidrug-resistant Enterobacteriaceae from blood cultures in Liverpool, United Kingdom. J. Antimicrob. Chemother. 56:1115-1117. (Pubitemid 43009830)
4. Díaz, M. A., R. K. Cooper, A. Cloeckaert, and R. J. Siebeling. 2006. Plasmidmediated high-level gentamicin resistance among enteric bacteria isolated from pet turtles in Louisiana. Appl. Environ. Microbiol. 72:306-312.
5. Eschenburg, S., M. Priestman, and E. Schönbrunn. 2005. Evidence that the fosfomycin target Cys115 in UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is essential for product release. J. Biol. Chem. 280:3757-3763.
6. Giakkoupi, P., et al. 2000. IBC-1, a novel integron-associated class A betalactamase with extended-spectrum properties produced by an Enterobacter cloacae clinical strain. Antimicrob. Agents Chemother. 44:2247-2253.
7. He, G. X., et al. 2004. An H(+)-coupled multidrug efflux pump, PmpM, a member of the MATE family of transporters, from Pseudomonas aeruginosa. J. Bacteriol. 186:262-265.
8. Hoang, T., R. RoxAnn, K. Schweizer, A. Kutchma, and H. Schweizer. 1998. A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutants. Gene 212:77-86. (Pubitemid 28269135)
9. Kaneko, K., R. Okamoto, R. Nakano, S. Kawakami, and M. Inoue. 2005. Gene mutations responsible for overexpression of AmpC beta-lactamase in some clinical isolates of Enterobacter cloacae. J. Clin. Microbiol. 43:2995-2998.
10. Keeney, D., A. Ruzin, and P. A. Bradford. 2007. RamA, a transcriptional regulator, and AcrAB, an RND-type efflux pump, are associated with decreased susceptibility to tigecycline in Enterobacter cloacae. Microb. Drug Resist. 13:1-6.
11. Leverstein-van Hall, M. A., et al. 2006. Extensive hospital-wide spread of a multidrug-resistant Enterobacter cloacae clone, with late detection due to a variable antibiogram and frequent patient transfer. J. Clin. Microbiol. 44: 518-524.
12. Levy, S. B. 2002. Active efflux, a common mechanism for biocide and antibiotic resistance. J. Appl. Microbiol. 92:65S-71S.
13. Li, W., J. S. Hartung, and L. Levy. 2006. Quantitative real-time PCR for detection and identification of Candidatus Liberibacter species associated with citrus huanglongbing. J. Microbiol. Methods 66:104-115.
14. Minato, Y., F. Shahcheraghi, W. Ogawa, T. Kuroda, and T. Tsuchiya. 2008. Functional gene cloning and characterization of the SsmE multidrug efflux pump from Serratia marcescens. Biol. Pharm. Bull. 31:516-519.
15. Mine, T., Y. Morita, A. Kataoka, T. Mizushima, and T. Tsuchiya. 1998. Evidence for chloramphenicol/H+ antiporter in Cmr (MdfA) system of Escherichia coli and properties of the antiporter. J. Biochem. 124:187-193. (Pubitemid 28379491)
16. Naiemi, N. A., et al. 2005. Widespread transfer of resistance genes between bacterial species in an intensive care unit: implications for hospital epidemiology. J. Clin. Microbiol. 43:4862-4864.
17. Paterson, D. L. 2006. Resistance in Gram-negative bacteria: Enterobacteriaceae. Am. J. Med. 119:S20-S28.
18. Pérez, A., et al. 2007. Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. Antimicrob. Agents Chemother. 51:3247-3253.
19. Ren, Y., et al. 2010. Complete genome sequence of Enterobacter cloacae subsp. cloacae type strain ATCC 13047. J. Bacteriol. 192:2463-2464.
20. Rhomberg, P. R., T. R. Fritsche, H. S. Sader, and R. N. Jones. 2006. Clonal occurrences of multidrug-resistant Gram-negative bacilli: report from the Meropenem Yearly Susceptibility Test Information Collection Surveillance Program in the United States 2001. Diagn. Microbiol. Infect. Dis. 54:249-257.
21. Weigel, L. M., C. D. Steward, and F. C. Tenover. 1998. gyrA mutations associated with fluoroquinolone resistance in eight species of Enterobacteriaceae. Antimicrob. Agents Chemother. 42:2661-2667.